Gene detail

NE604_RS12565

Histidine kinase, Hybrid

Anaerofustis stercorihominis · GCF_024460395

ClassHKTypeHybridLength869 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_024460395#NE604_RS12565Stable P2CS identifier used across views.
GenomeGCF_024460395Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Eubacteriaceae; Anaerofustis
Selected clusterHKOC_0460324Run 6 · 1 sequences · id 100% · cov 80% · representative
External referencesWP_256146215.1 · MIST4 NE604_RS12565RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_cResponse_reg
Protein length869 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage420 / 869 aa (48.3%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_c,2 Response_regSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa869 aa
HisKA: 358-424 aa (67 aa)1HATPase_c: 471-588 aa (118 aa)2Response_reg: 605-722 aa (118 aa)3Response_reg: 748-864 aa (117 aa)4
Domain-by-domain annotation4 items
1 HisKA#1
358-424 aa · 67 aa · 7.7% of protein
Raw tokenHisKA:358:0.000000000000012:424:67:64
2 HATPase_c#2
471-588 aa · 118 aa · 13.6% of protein
Raw tokenHATPase_c:471:9.59e-30:588:118:109
3 Response_reg#3
605-722 aa · 118 aa · 13.6% of protein
Raw tokenResponse_reg:605:2.22e-27:722:118:111
4 Response_reg#4
748-864 aa · 117 aa · 13.5% of protein
Raw tokenResponse_reg:748:7.02e-27:864:117:111
  • Raw architecture: HisKA:358:0.000000000000012:424:67:64#HATPase_c:471:9.59e-30:588:118:109#Response_reg:605:2.22e-27:722:118:111#Response_reg:748:7.02e-27:864:117:111
  • Domain description: 1 HisKA,1 HATPase_c,2 Response_reg
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_024460395::NZ_JANFYI010000001.1::G00005
Group size22 locus tags listed below.
HK / RR2 / 0Counts resolved for the local TCS neighborhood.
Context span523034-528434Genomic interval covered by the local TCS group.
Identifiers
Old locus tagNE604_02555RefSeq proteinWP_256146215.1
Context group IDGCF_024460395::NZ_JANFYI010000001.1::G00005
Context members
NE604_RS02550NE604_RS12565
Partner locus tags
NE604_RS02550NE604_RS12565
Partner old locus tags
NE604_02550NE604_02555
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_256146215.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagNE604_RS12565Primary locus identifier stored in the genes table.
Old locus tagNE604_02555Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JANFYI010000001.1Sequence record reported by the local genomic context database.
Genomic interval525 825-528 434 nt2 610 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span523 034-528 434 ntGCF_024460395::NZ_JANFYI010000001.1::G00005

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_024460395::NZ_JANFYI010000001.1::G00005

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JANFYI010000001.1All displayed genes belong to this local TCS context.
Neighborhood span523 034-528 434 nt5 401 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
523 034 nt528 434 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

NE604_RS02550GCF_024460395#NE604_RS02550
HKHybrid

523 034-525 652 nt · Reverse (-)

Old locus NE604_02550RefSeq WP_256146214.1
NE604_RS12565GCF_024460395#NE604_RS12565
HKHybridCurrent focus

525 825-528 434 nt · Reverse (-)

Old locus NE604_02555RefSeq WP_256146215.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0460324Run 6 · HK · 1 sequences
Representative sequenceGCF_024460395#NE604_RS12565The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c + Response_reg + Response_reg4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0460324

Simplified PFAM architecture for HKOC_0460324

PFAM domain coverage: 418 / 869 aa (48.1%)

1 aa869 aa
HisKA: 358-424 aaHisKAHATPase_c: 471-587 aaHATPase_cResponse_reg: 605-722 aaResponse_regResponse_reg: 748-863 aaResponse_reg
HisKAHATPase_cResponse_regResponse_reg
  • Simplified architecture: HisKA + HATPase_c + Response_reg + Response_reg
  • Raw architecture: HisKA[358-424] | HATPase_c[471-587] | Response_reg[605-722] | Response_reg[748-863]
  • Domain count: 4
  • Matched identifier: HKOC_0460324
  • Positioned domains: HisKA 358-424 ; HATPase_c 471-587 ; Response_reg 605-722 ; Response_reg 748-863
Cluster members and taxonomy
Visualization

Representative gene: GCF_024460395#NE604_RS12565

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 214 853 · GCF_024460395
AssemblyASM2446039v1 · Contighaploid
Genome composition2 407 739 bp · 34,0% GCAnaerofustis stercorihominis
Signal transduction countsGenes 40 · HK 24 · RR 15CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyEubacteriaceaeGenusAnaerofustis
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Eubacteriaceae7Anaerofustis

Related genes

Preview from the same derived genome key