P2CS-Web

Two-component systems, rebuilt for exploration

Gene detail

NE604_RS01825

Histidine kinase, Hybrid

Anaerofustis stercorihominis · GCF_024460395

Open genomeOpen selected clusterRefSeq
ClassHKTypeHybridLength1210 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_024460395#NE604_RS01825Stable P2CS identifier used across views.
GenomeGCF_024460395Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Eubacteriaceae; Anaerofustis
Selected clusterHKOC_0153140Run 6 · 1 sequences · id 100% · cov 80% · representative
External referencesWP_256146166.1 · MIST4 NE604_RS01825RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

PAS_3HisKAHATPase_cResponse_reg
Protein length1210 aaLength used to scale native and Biotite-like views.
Annotated domains77 with usable coordinates.
Domain coverage626 / 1210 aa (51.7%)Merged over positioned domains only.
Domain description3 PAS_3,1 HisKA,1 HATPase_c,2 Response_regSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Domain view
NativeBiotite-like
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa1210 aa
PAS_3: 174-249 aa (76 aa)1PAS_3: 317-399 aa (83 aa)2PAS_3: 449-533 aa (85 aa)3HisKA: 700-766 aa (67 aa)4HATPase_c: 813-924 aa (112 aa)5Response_reg: 947-1031 aa (85 aa)6Response_reg: 1088-1205 aa (118 aa)7
Domain-by-domain annotation7 items
1 PAS_3#1
174-249 aa · 76 aa · 6.3% of protein
Raw tokenPAS_3:174:0.0000000029:249:77:89
2 PAS_3#2
317-399 aa · 83 aa · 6.9% of protein
Raw tokenPAS_3:317:0.0000000000000417:399:83:89
3 PAS_3#3
449-533 aa · 85 aa · 7.0% of protein
Raw tokenPAS_3:449:2.87e-17:533:85:89
4 HisKA#4
700-766 aa · 67 aa · 5.5% of protein
Raw tokenHisKA:700:8.64e-18:766:67:64
5 HATPase_c#5
813-924 aa · 112 aa · 9.3% of protein
Raw tokenHATPase_c:813:1.32e-27:924:112:109
6 Response_reg#6
947-1031 aa · 85 aa · 7.0% of protein
Raw tokenResponse_reg:947:0.000000000000313:1031:85:111
7 Response_reg#7
1088-1205 aa · 118 aa · 9.8% of protein
Raw tokenResponse_reg:1088:6.17e-26:1205:118:111
  • Raw architecture: PAS_3:174:0.0000000029:249:77:89#PAS_3:317:0.0000000000000417:399:83:89#PAS_3:449:2.87e-17:533:85:89#HisKA:700:8.64e-18:766:67:64#HATPase_c:813:1.32e-27:924:112:109#Response_reg:947:0.000000000000313:1031:85:111#Response_reg:1088:6.17e-26:1205:118:111
  • Domain description: 3 PAS_3,1 HisKA,1 HATPase_c,2 Response_reg
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_024460395::NZ_JANFYI010000001.1::G00003
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span378339-383084Genomic interval covered by the local TCS group.
Identifiers
Old locus tagNE604_01825RefSeq proteinWP_256146166.1
Context group IDGCF_024460395::NZ_JANFYI010000001.1::G00003
Context members
NE604_RS01820NE604_RS01825
Partner locus tags
NE604_RS01820NE604_RS01825
Partner old locus tags
NE604_01820NE604_01825
Partner protein IDs
WP_117532117.1WP_256146166.1

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_256146166.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagNE604_RS01825Primary locus identifier stored in the genes table.
Old locus tagNE604_01825Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JANFYI010000001.1Sequence record reported by the local genomic context database.
Genomic interval379 452-383 084 nt3 633 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span378 339-383 084 ntGCF_024460395::NZ_JANFYI010000001.1::G00003
Quick actions
Open genomeSearch genes in genome

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_024460395::NZ_JANFYI010000001.1::G00003
Graphic view
CompactBiotite-like
Zoom
Full windowFocus gene

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JANFYI010000001.1All displayed genes belong to this local TCS context.
Neighborhood span378 339-383 084 nt4 746 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
378 339 nt383 084 nt
+-NE604_RS01820NE604_RS01825
Neighborhood gene cards

2 genes in the current local neighborhood.

NE604_RS01820GCF_024460395#NE604_RS01820
RRRpfG

378 339-379 427 nt · Forward (+)

Old locus NE604_01820RefSeq WP_117532117.1
Open gene
NE604_RS01825GCF_024460395#NE604_RS01825
HKHybridCurrent focus

379 452-383 084 nt · Forward (+)

Old locus NE604_01825RefSeq WP_256146166.1
Open current gene

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Available memberships1 cluster
HKOC_0153140HK
Run 61 sequencesid 100%cov 80%
PFAM PAS_3 + PAS_3 + PAS_3 + HisKA + HATPase_c + Response_reg + Response_reg
Current gene is the representative sequence.
Selected clusterHKOC_0153140Run 6 · HK · 1 sequences
Representative sequenceGCF_024460395#NE604_RS01825The current gene is the representative for this cluster.
PFAM architecturePAS_3 + PAS_3 + PAS_3 + HisKA + HATPase_c + Response_reg + Response_reg7 domains in the representative PFAM annotation.
Open in cluster search

PFAM architecture for HKOC_0153140

Simplified PFAM architecture for HKOC_0153140

PFAM domain coverage: 652 / 1210 aa (53.9%)

1 aa1210 aa
PAS_3: 175-249 aaPAS_3PAS_3: 318-399 aaPAS_3PAS_3: 450-532 aaPAS_3HisKA: 700-766 aaHisKAHATPase_c: 813-925 aaHATPase_cResponse_reg: 947-1061 aaResponse_regResponse_reg: 1088-1204 aaResponse_reg
PAS_3PAS_3PAS_3HisKAHATPase_cResponse_regResponse_reg
  • Simplified architecture: PAS_3 + PAS_3 + PAS_3 + HisKA + HATPase_c + Response_reg + Response_reg
  • Raw architecture: PAS_3[175-249] | PAS_3[318-399] | PAS_3[450-532] | HisKA[700-766] | HATPase_c[813-925] | Response_reg[947-1061] | Response_reg[1088-1204]
  • Domain count: 7
  • Matched identifier: HKOC_0153140
  • Positioned domains: PAS_3 175-249 ; PAS_3 318-399 ; PAS_3 450-532 ; HisKA 700-766 ; HATPase_c 813-925 ; Response_reg 947-1061 ; Response_reg 1088-1204
Cluster members and taxonomy
Visualization
SankeyMember list

Representative gene: GCF_024460395#NE604_RS01825

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 214 853 · GCF_024460395
AssemblyASM2446039v1 · Contighaploid
Genome composition2 407 739 bp · 34,0% GCAnaerofustis stercorihominis
Signal transduction countsGenes 40 · HK 24 · RR 15CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyEubacteriaceaeGenusAnaerofustis
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Eubacteriaceae7Anaerofustis
Open genomeSearch genes in genomeSearch HK genesNCBI assembly files

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