Gene detail

NE604_RS02740

Histidine kinase, Hybrid

Anaerofustis stercorihominis · GCF_024460395

ClassHKTypeHybridLength928 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_024460395#NE604_RS02740Stable P2CS identifier used across views.
GenomeGCF_024460395Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Eubacteriaceae; Anaerofustis
Selected clusterHKOC_0355312Run 6 · 3 sequences · id 100% · cov 80%
External referencesWP_007049424.1 · B1C8C3 · MIST4 NE604_RS02740RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

PAS_3HisKAHATPase_cResponse_reg
Protein length928 aaLength used to scale native and Biotite-like views.
Annotated domains55 with usable coordinates.
Domain coverage480 / 928 aa (51.7%)Merged over positioned domains only.
Domain description1 PAS_3,1 HisKA,1 HATPase_c,2 Response_regSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa928 aa
PAS_3: 305-363 aa (59 aa)1HisKA: 418-484 aa (67 aa)2HATPase_c: 531-649 aa (119 aa)3Response_reg: 665-781 aa (117 aa)4Response_reg: 807-924 aa (118 aa)5
Domain-by-domain annotation5 items
1 PAS_3#1
305-363 aa · 59 aa · 6.4% of protein
Raw tokenPAS_3:305:0.000000000441:363:59:89
2 HisKA#2
418-484 aa · 67 aa · 7.2% of protein
Raw tokenHisKA:418:3.83e-18:484:67:64
3 HATPase_c#3
531-649 aa · 119 aa · 12.8% of protein
Raw tokenHATPase_c:531:6.23e-30:649:119:109
4 Response_reg#4
665-781 aa · 117 aa · 12.6% of protein
Raw tokenResponse_reg:665:2.7e-23:781:117:111
5 Response_reg#5
807-924 aa · 118 aa · 12.7% of protein
Raw tokenResponse_reg:807:1.09e-27:924:118:111
  • Raw architecture: PAS_3:305:0.000000000441:363:59:89#HisKA:418:3.83e-18:484:67:64#HATPase_c:531:6.23e-30:649:119:109#Response_reg:665:2.7e-23:781:117:111#Response_reg:807:1.09e-27:924:118:111
  • Domain description: 1 PAS_3,1 HisKA,1 HATPase_c,2 Response_reg
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_024460395::NZ_JANFYI010000001.1::G00006
Group size22 locus tags listed below.
HK / RR2 / 0Counts resolved for the local TCS neighborhood.
Context span576512-581259Genomic interval covered by the local TCS group.
Identifiers
Old locus tagNE604_02740RefSeq proteinWP_007049424.1
Context group IDGCF_024460395::NZ_JANFYI010000001.1::G00006
Context members
NE604_RS02740NE604_RS02745
Partner locus tags
NE604_RS02740NE604_RS02745
Partner old locus tags
NE604_02740NE604_02745
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_007049424.1Primary protein accession used for annex mappings.
UniProt accessionB1C8C3Primary UniProt accession resolved in the annex database.
UniProt IDB1C8C3_9FIRMDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagNE604_RS02740Primary locus identifier stored in the genes table.
Old locus tagNE604_02740Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JANFYI010000001.1Sequence record reported by the local genomic context database.
Genomic interval576 512-579 298 nt2 787 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span576 512-581 259 ntGCF_024460395::NZ_JANFYI010000001.1::G00006

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_024460395::NZ_JANFYI010000001.1::G00006

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JANFYI010000001.1All displayed genes belong to this local TCS context.
Neighborhood span576 512-581 259 nt4 748 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
576 512 nt581 259 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

NE604_RS02740GCF_024460395#NE604_RS02740
HKHybridCurrent focus

576 512-579 298 nt · Reverse (-)

Old locus NE604_02740RefSeq WP_007049424.1
NE604_RS02745GCF_024460395#NE604_RS02745
HKHybrid

579 484-581 259 nt · Reverse (-)

Old locus NE604_02745RefSeq WP_256146226.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0355312Run 6 · HK · 3 sequences
Representative sequenceGCF_000154825#ANASTE_RS02925Use this link to inspect the representative gene detail.
PFAM architecturePAS_3 + HisKA + HATPase_c + Response_reg + Response_reg5 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0355312

Simplified PFAM architecture for HKOC_0355312

PFAM domain coverage: 479 / 928 aa (51.6%)

1 aa928 aa
PAS_3: 304-365 aaPAS_3HisKA: 418-484 aaHisKAHATPase_c: 532-648 aaHATPase_cResponse_reg: 665-780 aaResponse_regResponse_reg: 807-923 aaResponse_reg
PAS_3HisKAHATPase_cResponse_regResponse_reg
  • Simplified architecture: PAS_3 + HisKA + HATPase_c + Response_reg + Response_reg
  • Raw architecture: PAS_3[304-365] | HisKA[418-484] | HATPase_c[532-648] | Response_reg[665-780] | Response_reg[807-923]
  • Domain count: 5
  • Matched identifier: HKOC_0355312
  • Positioned domains: PAS_3 304-365 ; HisKA 418-484 ; HATPase_c 532-648 ; Response_reg 665-780 ; Response_reg 807-923
Cluster members and taxonomy
Visualization

Representative gene: GCF_000154825#ANASTE_RS02925

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 214 853 · GCF_024460395
AssemblyASM2446039v1 · Contighaploid
Genome composition2 407 739 bp · 34,0% GCAnaerofustis stercorihominis
Signal transduction countsGenes 40 · HK 24 · RR 15CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyEubacteriaceaeGenusAnaerofustis
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Eubacteriaceae7Anaerofustis

Related genes

Preview from the same derived genome key