1 HisKA#1
218-283 aa · 66 aa · 11.2% of protein
Raw token
HisKA:218:4.68e-18:283:66:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
NE604_RS02745
Histidine kinase, Hybrid
Anaerofustis stercorihominis · GCF_024460395
ClassHKTypeHybridLength591 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_024460395#NE604_RS02745Stable P2CS identifier used across views.
GenomeGCF_024460395Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Eubacteriaceae; Anaerofustis
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_cResponse_reg
Protein length591 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage298 / 591 aa (50.4%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_c,1 Response_regSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa591 aa
Domain-by-domain annotation3 items
2 HATPase_c#2
332-446 aa · 115 aa · 19.5% of protein
Raw token
HATPase_c:332:2.86e-32:446:115:1093 Response_reg#3
469-585 aa · 117 aa · 19.8% of protein
Raw token
Response_reg:469:3.6e-26:585:117:111- Raw architecture: HisKA:218:4.68e-18:283:66:64#HATPase_c:332:2.86e-32:446:115:109#Response_reg:469:3.6e-26:585:117:111
- Domain description: 1 HisKA,1 HATPase_c,1 Response_reg
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_024460395::NZ_JANFYI010000001.1::G00006
Group size22 locus tags listed below.
HK / RR2 / 0Counts resolved for the local TCS neighborhood.
Context span576512-581259Genomic interval covered by the local TCS group.
Identifiers
Old locus tagNE604_02745RefSeq proteinWP_256146226.1
Context group ID
GCF_024460395::NZ_JANFYI010000001.1::G00006Context members
NE604_RS02740NE604_RS02745
Partner locus tags
NE604_RS02740NE604_RS02745
Partner old locus tags
NE604_02740NE604_02745
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_256146226.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagNE604_RS02745Primary locus identifier stored in the genes table.
Old locus tagNE604_02745Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JANFYI010000001.1Sequence record reported by the local genomic context database.
Genomic interval579 484-581 259 nt1 776 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span576 512-581 259 ntGCF_024460395::NZ_JANFYI010000001.1::G00006
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_024460395::NZ_JANFYI010000001.1::G00006Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JANFYI010000001.1All displayed genes belong to this local TCS context.
Neighborhood span576 512-581 259 nt4 748 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
576 512 nt581 259 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
NE604_RS02740GCF_024460395#NE604_RS02740
HKHybrid
576 512-579 298 nt · Reverse (-)
NE604_RS02745GCF_024460395#NE604_RS02745
HKHybridCurrent focus
579 484-581 259 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_024460395#NE604_RS02745The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c + Response_reg3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1107998
Simplified PFAM architecture for HKOC_1107998
PFAM domain coverage: 296 / 591 aa (50.1%)
1 aa591 aa
HisKAHATPase_cResponse_reg
- Simplified architecture: HisKA + HATPase_c + Response_reg
- Raw architecture: HisKA[218-283] | HATPase_c[332-444] | Response_reg[469-585]
- Domain count: 3
- Matched identifier: HKOC_1107998
- Positioned domains: HisKA 218-283 ; HATPase_c 332-444 ; Response_reg 469-585
Cluster members and taxonomy
Representative gene: GCF_024460395#NE604_RS02745
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 214 853 · GCF_024460395
AssemblyASM2446039v1 · Contighaploid
Genome composition2 407 739 bp · 34,0% GCAnaerofustis stercorihominis
Signal transduction countsGenes 40 · HK 24 · RR 15CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyEubacteriaceaeGenusAnaerofustis
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Eubacteriaceae7Anaerofustis
Related genes
Preview from the same derived genome key