Gene detail

NE604_RS10040

Histidine kinase, Hybrid

Anaerofustis stercorihominis · GCF_024460395

ClassHKTypeHybridLength617 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_024460395#NE604_RS10040Stable P2CS identifier used across views.
GenomeGCF_024460395Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Eubacteriaceae; Anaerofustis
Selected clusterHKOC_0981954Run 6 · 3 sequences · id 100% · cov 80%
External referencesWP_007050448.1 · B1C8R8 · MIST4 NE604_RS10040RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

H_kinase_NHisKAHATPase_cResponse_reg
Protein length617 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage373 / 617 aa (60.5%)Merged over positioned domains only.
Domain description1 H_kinase_N,1 HisKA,1 HATPase_c,1 Response_regSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa617 aa
H_kinase_N: 125-196 aa (72 aa)1HisKA: 238-304 aa (67 aa)2HATPase_c: 350-465 aa (116 aa)3Response_reg: 496-613 aa (118 aa)4
Domain-by-domain annotation4 items
1 H_kinase_N#1
125-196 aa · 72 aa · 11.7% of protein
Raw tokenH_kinase_N:125:0.0000713:196:82:139
2 HisKA#2
238-304 aa · 67 aa · 10.9% of protein
Raw tokenHisKA:238:2.96e-19:304:67:64
3 HATPase_c#3
350-465 aa · 116 aa · 18.8% of protein
Raw tokenHATPase_c:350:5.5e-29:465:116:109
4 Response_reg#4
496-613 aa · 118 aa · 19.1% of protein
Raw tokenResponse_reg:496:4.68e-31:613:118:111
  • Raw architecture: H_kinase_N:125:0.0000713:196:82:139#HisKA:238:2.96e-19:304:67:64#HATPase_c:350:5.5e-29:465:116:109#Response_reg:496:4.68e-31:613:118:111
  • Domain description: 1 H_kinase_N,1 HisKA,1 HATPase_c,1 Response_reg
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_024460395::NZ_JANFYI010000230.1::G00011
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span90106-91959Genomic interval covered by the local TCS group.
Identifiers
Old locus tagNE604_10040RefSeq proteinWP_007050448.1
Context group IDGCF_024460395::NZ_JANFYI010000230.1::G00011
Context members
NE604_RS10040
Partner locus tags
NE604_RS10040
Partner old locus tags
NE604_10040
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_007050448.1Primary protein accession used for annex mappings.
UniProt accessionB1C8R8Primary UniProt accession resolved in the annex database.
UniProt IDB1C8R8_9FIRMDisplay identifier provided by UniProt.
GO / PubMed1 / 0Unique GO terms and literature references available below.
GO terms

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagNE604_RS10040Primary locus identifier stored in the genes table.
Old locus tagNE604_10040Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JANFYI010000230.1Sequence record reported by the local genomic context database.
Genomic interval90 106-91 959 nt1 854 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span90 106-91 959 ntGCF_024460395::NZ_JANFYI010000230.1::G00011

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_024460395::NZ_JANFYI010000230.1::G00011

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JANFYI010000230.1All displayed genes belong to this local TCS context.
Neighborhood span90 106-91 959 nt1 854 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
90 106 nt91 959 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

NE604_RS10040GCF_024460395#NE604_RS10040
HKHybridCurrent focus

90 106-91 959 nt · Reverse (-)

Old locus NE604_10040RefSeq WP_007050448.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0981954Run 6 · HK · 3 sequences
Representative sequenceGCF_000154825#ANASTE_RS11480Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c + Response_reg3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0981954

Simplified PFAM architecture for HKOC_0981954

PFAM domain coverage: 300 / 617 aa (48.6%)

1 aa617 aa
HisKA: 238-304 aaHisKAHATPase_c: 350-465 aaHATPase_cResponse_reg: 496-612 aaResponse_reg
HisKAHATPase_cResponse_reg
  • Simplified architecture: HisKA + HATPase_c + Response_reg
  • Raw architecture: HisKA[238-304] | HATPase_c[350-465] | Response_reg[496-612]
  • Domain count: 3
  • Matched identifier: HKOC_0981954
  • Positioned domains: HisKA 238-304 ; HATPase_c 350-465 ; Response_reg 496-612
Cluster members and taxonomy
Visualization

Representative gene: GCF_000154825#ANASTE_RS11480

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 214 853 · GCF_024460395
AssemblyASM2446039v1 · Contighaploid
Genome composition2 407 739 bp · 34,0% GCAnaerofustis stercorihominis
Signal transduction countsGenes 40 · HK 24 · RR 15CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyEubacteriaceaeGenusAnaerofustis
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Eubacteriaceae7Anaerofustis

Related genes

Preview from the same derived genome key