Gene detail

NE604_RS08980

Histidine kinase, Hybrid

Anaerofustis stercorihominis · GCF_024460395

ClassHKTypeHybridLength1313 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_024460395#NE604_RS08980Stable P2CS identifier used across views.
GenomeGCF_024460395Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Eubacteriaceae; Anaerofustis
Selected clusterHKOC_0119614Run 6 · 1 sequences · id 100% · cov 80% · representative
External referencesWP_256146716.1 · MIST4 NE604_RS08980RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPPACGGDEFHisKAHATPase_cResponse_reg
Protein length1313 aaLength used to scale native and Biotite-like views.
Annotated domains66 with usable coordinates.
Domain coverage533 / 1313 aa (40.6%)Merged over positioned domains only.
Domain description1 HAMP,1 PAC,1 GGDEF,1 HisKA,1 HATPase_c,1 Response_regSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa1313 aa
HAMP: 380-433 aa (54 aa)1PAC: 547-578 aa (32 aa)GGDEF: 591-739 aa (149 aa)3HisKA: 939-1005 aa (67 aa)4HATPase_c: 1051-1164 aa (114 aa)5Response_reg: 1191-1307 aa (117 aa)6
Domain-by-domain annotation6 items
1 HAMP#1
380-433 aa · 54 aa · 4.1% of protein
Raw tokenHAMP:380:0.00000769:433:54:69
2 PAC#2
547-578 aa · 32 aa · 2.4% of protein
Raw tokenPAC:547:0.000022:578:32:43
3 GGDEF#3
591-739 aa · 149 aa · 11.3% of protein
Raw tokenGGDEF:591:2.76e-21:739:162:160
4 HisKA#4
939-1005 aa · 67 aa · 5.1% of protein
Raw tokenHisKA:939:5.41e-19:1005:67:64
5 HATPase_c#5
1051-1164 aa · 114 aa · 8.7% of protein
Raw tokenHATPase_c:1051:1.89e-27:1164:114:109
6 Response_reg#6
1191-1307 aa · 117 aa · 8.9% of protein
Raw tokenResponse_reg:1191:1.93e-31:1307:117:111
  • Raw architecture: HAMP:380:0.00000769:433:54:69#PAC:547:0.000022:578:32:43#GGDEF:591:2.76e-21:739:162:160#HisKA:939:5.41e-19:1005:67:64#HATPase_c:1051:1.89e-27:1164:114:109#Response_reg:1191:1.93e-31:1307:117:111
  • Domain description: 1 HAMP,1 PAC,1 GGDEF,1 HisKA,1 HATPase_c,1 Response_reg
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_024460395::NZ_JANFYI010000229.1::G00017
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span7613-11554Genomic interval covered by the local TCS group.
Identifiers
Old locus tagNE604_08980RefSeq proteinWP_256146716.1
Context group IDGCF_024460395::NZ_JANFYI010000229.1::G00017
Context members
NE604_RS08980
Partner locus tags
NE604_RS08980
Partner old locus tags
NE604_08980
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_256146716.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagNE604_RS08980Primary locus identifier stored in the genes table.
Old locus tagNE604_08980Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JANFYI010000229.1Sequence record reported by the local genomic context database.
Genomic interval7 613-11 554 nt3 942 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span7 613-11 554 ntGCF_024460395::NZ_JANFYI010000229.1::G00017

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_024460395::NZ_JANFYI010000229.1::G00017

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JANFYI010000229.1All displayed genes belong to this local TCS context.
Neighborhood span7 613-11 554 nt3 942 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
7 613 nt11 554 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

NE604_RS08980GCF_024460395#NE604_RS08980
HKHybridCurrent focus

7 613-11 554 nt · Forward (+)

Old locus NE604_08980RefSeq WP_256146716.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0119614Run 6 · HK · 1 sequences
Representative sequenceGCF_024460395#NE604_RS08980The current gene is the representative for this cluster.
PFAM architectureMCP-like_PDC_1 + GGDEF + HisKA + HATPase_c + Response_reg5 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0119614

Simplified PFAM architecture for HKOC_0119614

PFAM domain coverage: 496 / 1313 aa (37.8%)

1 aa1313 aa
MCP-like_PDC_1: 213-262 aaGGDEF: 591-738 aaGGDEFHisKA: 939-1005 aaHATPase_c: 1051-1166 aaHATPase_cResponse_reg: 1191-1305 aaResponse_reg
MCP-like_PDC_1GGDEFHisKAHATPase_cResponse_reg
  • Simplified architecture: MCP-like_PDC_1 + GGDEF + HisKA + HATPase_c + Response_reg
  • Raw architecture: MCP-like_PDC_1[213-262] | GGDEF[591-738] | HisKA[939-1005] | HATPase_c[1051-1166] | Response_reg[1191-1305]
  • Domain count: 5
  • Matched identifier: HKOC_0119614
  • Positioned domains: MCP-like_PDC_1 213-262 ; GGDEF 591-738 ; HisKA 939-1005 ; HATPase_c 1051-1166 ; Response_reg 1191-1305
Cluster members and taxonomy
Visualization

Representative gene: GCF_024460395#NE604_RS08980

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 214 853 · GCF_024460395
AssemblyASM2446039v1 · Contighaploid
Genome composition2 407 739 bp · 34,0% GCAnaerofustis stercorihominis
Signal transduction countsGenes 40 · HK 24 · RR 15CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyEubacteriaceaeGenusAnaerofustis
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Eubacteriaceae7Anaerofustis

Related genes

Preview from the same derived genome key