Gene detail

NE604_RS00460

Histidine kinase, Hybrid

Anaerofustis stercorihominis · GCF_024460395

ClassHKTypeHybridLength964 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_024460395#NE604_RS00460Stable P2CS identifier used across views.
GenomeGCF_024460395Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Eubacteriaceae; Anaerofustis
Selected clusterHKOC_0315665Run 6 · 1 sequences · id 100% · cov 80% · representative
External referencesWP_256146053.1 · MIST4 NE604_RS00460RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

PTS_EIICHisKAHATPase_cResponse_reg
Protein length964 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage620 / 964 aa (64.3%)Merged over positioned domains only.
Domain description1 PTS_EIIC,1 HisKA,1 HATPase_c,1 Response_regSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa964 aa
PTS_EIIC: 27-347 aa (321 aa)1HisKA: 587-653 aa (67 aa)2HATPase_c: 699-816 aa (118 aa)3Response_reg: 843-956 aa (114 aa)4
Domain-by-domain annotation4 items
1 PTS_EIIC#1
27-347 aa · 321 aa · 33.3% of protein
Raw tokenPTS_EIIC:27:2.93e-27:347:333:315
2 HisKA#2
587-653 aa · 67 aa · 7.0% of protein
Raw tokenHisKA:587:5.02e-18:653:67:64
3 HATPase_c#3
699-816 aa · 118 aa · 12.2% of protein
Raw tokenHATPase_c:699:8.32e-27:816:118:109
4 Response_reg#4
843-956 aa · 114 aa · 11.8% of protein
Raw tokenResponse_reg:843:9.36e-28:956:114:111
  • Raw architecture: PTS_EIIC:27:2.93e-27:347:333:315#HisKA:587:5.02e-18:653:67:64#HATPase_c:699:8.32e-27:816:118:109#Response_reg:843:9.36e-28:956:114:111
  • Domain description: 1 PTS_EIIC,1 HisKA,1 HATPase_c,1 Response_reg
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_024460395::NZ_JANFYI010000001.1::G00002
Group size22 locus tags listed below.
HK / RR2 / 0Counts resolved for the local TCS neighborhood.
Context span109121-114944Genomic interval covered by the local TCS group.
Identifiers
Old locus tagNE604_00460RefSeq proteinWP_256146053.1
Context group IDGCF_024460395::NZ_JANFYI010000001.1::G00002
Context members
NE604_RS00455NE604_RS00460
Partner locus tags
NE604_RS00455NE604_RS00460
Partner old locus tags
NE604_00455NE604_00460
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_256146053.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagNE604_RS00460Primary locus identifier stored in the genes table.
Old locus tagNE604_00460Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JANFYI010000001.1Sequence record reported by the local genomic context database.
Genomic interval112 050-114 944 nt2 895 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span109 121-114 944 ntGCF_024460395::NZ_JANFYI010000001.1::G00002

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_024460395::NZ_JANFYI010000001.1::G00002

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JANFYI010000001.1All displayed genes belong to this local TCS context.
Neighborhood span109 121-114 944 nt5 824 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
109 121 nt114 944 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

NE604_RS00455GCF_024460395#NE604_RS00455
HKHybrid

109 121-111 868 nt · Forward (+)

Old locus NE604_00455RefSeq WP_256146052.1
NE604_RS00460GCF_024460395#NE604_RS00460
HKHybridCurrent focus

112 050-114 944 nt · Forward (+)

Old locus NE604_00460RefSeq WP_256146053.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0315665Run 6 · HK · 1 sequences
Representative sequenceGCF_024460395#NE604_RS00460The current gene is the representative for this cluster.
PFAM architecturePTS_EIIC + HisKA + HATPase_c + Response_reg4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0315665

Simplified PFAM architecture for HKOC_0315665

PFAM domain coverage: 622 / 964 aa (64.5%)

1 aa964 aa
PTS_EIIC: 27-347 aaPTS_EIICHisKA: 587-653 aaHisKAHATPase_c: 699-816 aaHATPase_cResponse_reg: 843-958 aaResponse_reg
PTS_EIICHisKAHATPase_cResponse_reg
  • Simplified architecture: PTS_EIIC + HisKA + HATPase_c + Response_reg
  • Raw architecture: PTS_EIIC[27-347] | HisKA[587-653] | HATPase_c[699-816] | Response_reg[843-958]
  • Domain count: 4
  • Matched identifier: HKOC_0315665
  • Positioned domains: PTS_EIIC 27-347 ; HisKA 587-653 ; HATPase_c 699-816 ; Response_reg 843-958
Cluster members and taxonomy
Visualization

Representative gene: GCF_024460395#NE604_RS00460

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 214 853 · GCF_024460395
AssemblyASM2446039v1 · Contighaploid
Genome composition2 407 739 bp · 34,0% GCAnaerofustis stercorihominis
Signal transduction countsGenes 40 · HK 24 · RR 15CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyEubacteriaceaeGenusAnaerofustis
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Eubacteriaceae7Anaerofustis

Related genes

Preview from the same derived genome key