Gene detail

HMPREF9436_RS01875

Histidine kinase, Classic

Faecalibacterium cf. prausnitzii KLE1255 · GCF_000166035

ClassHKTypeClassicLength506 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000166035#HMPREF9436_RS01875Stable P2CS identifier used across views.
GenomeGCF_000166035Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae; Faecalibacterium
Selected clusterHKOC_1444075Run 6 · 4 sequences · id 100% · cov 80% · representative
External referencesWP_005938288.1 · E2ZFL6 · MIST4 HMPREF9436_RS01875RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length506 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage247 / 506 aa (48.8%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa506 aa
HAMP: 179-248 aa (70 aa)1HisKA: 253-319 aa (67 aa)2HATPase_c: 365-474 aa (110 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
179-248 aa · 70 aa · 13.8% of protein
Raw tokenHAMP:179:0.0000000000000427:248:70:69
2 HisKA#2
253-319 aa · 67 aa · 13.2% of protein
Raw tokenHisKA:253:7.13e-19:319:67:64
3 HATPase_c#3
365-474 aa · 110 aa · 21.7% of protein
Raw tokenHATPase_c:365:4.21e-30:474:110:109
  • Raw architecture: HAMP:179:0.0000000000000427:248:70:69#HisKA:253:7.13e-19:319:67:64#HATPase_c:365:4.21e-30:474:110:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000166035::NZ_GL538239.1::G00004
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span14833-17051Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9436_00449RefSeq proteinWP_005938288.1
Context group IDGCF_000166035::NZ_GL538239.1::G00004
Context members
HMPREF9436_RS01870HMPREF9436_RS01875
Partner locus tags
HMPREF9436_RS01870HMPREF9436_RS01875
Partner old locus tags
HMPREF9436_00448HMPREF9436_00449
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_005938288.1Primary protein accession used for annex mappings.
UniProt accessionE2ZFL6Primary UniProt accession resolved in the annex database.
UniProt IDE2ZFL6_9FIRMDisplay identifier provided by UniProt.
GO / PubMed6 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF9436_RS01875Primary locus identifier stored in the genes table.
Old locus tagHMPREF9436_00449Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GL538239.1Sequence record reported by the local genomic context database.
Genomic interval15 531-17 051 nt1 521 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span14 833-17 051 ntGCF_000166035::NZ_GL538239.1::G00004

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000166035::NZ_GL538239.1::G00004

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GL538239.1All displayed genes belong to this local TCS context.
Neighborhood span14 833-17 051 nt2 219 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
14 833 nt17 051 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

HMPREF9436_RS01870GCF_000166035#HMPREF9436_RS01870
RROmpR

14 833-15 531 nt · Forward (+)

Old locus HMPREF9436_00448RefSeq WP_005938284.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1444075Run 6 · HK · 4 sequences
Representative sequenceGCF_000166035#HMPREF9436_RS01875The current gene is the representative for this cluster.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1444075

Simplified PFAM architecture for HKOC_1444075

PFAM domain coverage: 229 / 506 aa (45.3%)

1 aa506 aa
HAMP: 197-248 aaHAMPHisKA: 253-319 aaHisKAHATPase_c: 366-475 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[197-248] | HisKA[253-319] | HATPase_c[366-475]
  • Domain count: 3
  • Matched identifier: HKOC_1444075
  • Positioned domains: HAMP 197-248 ; HisKA 253-319 ; HATPase_c 366-475
Cluster members and taxonomy
Visualization

Representative gene: GCF_000166035#HMPREF9436_RS01875

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 748 224 · GCF_000166035
AssemblyASM16603v1 · Scaffoldhaploid
Genome composition2 928 734 bp · 56,5% GCFaecalibacterium cf. prausnitzii KLE1255
Signal transduction countsGenes 48 · HK 21 · RR 25CheA 0 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyOscillospiraceaeGenusFaecalibacterium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Oscillospiraceae7Faecalibacterium

Related genes

Preview from the same derived genome key