Gene detail

HMPREF9436_RS00400

Histidine kinase, Classic

Faecalibacterium cf. prausnitzii KLE1255 · GCF_000166035

ClassHKTypeClassicLength507 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000166035#HMPREF9436_RS00400Stable P2CS identifier used across views.
GenomeGCF_000166035Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae; Faecalibacterium
Selected clusterHKOC_1440472Run 6 · 3 sequences · id 100% · cov 80% · representative
External referencesWP_242821905.1 · MIST4 HMPREF9436_RS00400RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHis_kinaseHATPase_c
Protein length507 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage254 / 507 aa (50.1%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa507 aa
HAMP: 194-262 aa (69 aa)1His_kinase: 294-373 aa (80 aa)2HATPase_c: 394-498 aa (105 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
194-262 aa · 69 aa · 13.6% of protein
Raw tokenHAMP:194:0.000000025:262:69:69
2 His_kinase#2
294-373 aa · 80 aa · 15.8% of protein
Raw tokenHis_kinase:294:1.15e-27:373:80:80
3 HATPase_c#3
394-498 aa · 105 aa · 20.7% of protein
Raw tokenHATPase_c:394:0.0000000000000202:498:108:109
  • Raw architecture: HAMP:194:0.000000025:262:69:69#His_kinase:294:1.15e-27:373:80:80#HATPase_c:394:0.0000000000000202:498:108:109
  • Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000166035::NZ_GL538226.1::G00001
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span6516-8845Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9436_00101RefSeq proteinWP_242821905.1
Context group IDGCF_000166035::NZ_GL538226.1::G00001
Context members
HMPREF9436_RS00400HMPREF9436_RS00405
Partner locus tags
HMPREF9436_RS00400HMPREF9436_RS00405
Partner old locus tags
HMPREF9436_00101HMPREF9436_00102
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_242821905.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF9436_RS00400Primary locus identifier stored in the genes table.
Old locus tagHMPREF9436_00101Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GL538226.1Sequence record reported by the local genomic context database.
Genomic interval6 516-8 039 nt1 524 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span6 516-8 845 ntGCF_000166035::NZ_GL538226.1::G00001

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000166035::NZ_GL538226.1::G00001

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GL538226.1All displayed genes belong to this local TCS context.
Neighborhood span6 516-8 845 nt2 330 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
6 516 nt8 845 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

HMPREF9436_RS00405GCF_000166035#HMPREF9436_RS00405
RRunclassified

8 036-8 845 nt · Forward (+)

Old locus HMPREF9436_00102RefSeq WP_005937194.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1440472Run 6 · HK · 3 sequences
Representative sequenceGCF_000166035#HMPREF9436_RS00400The current gene is the representative for this cluster.
PFAM architectureHAMP + His_kinase + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1440472

Simplified PFAM architecture for HKOC_1440472

PFAM domain coverage: 233 / 507 aa (46.0%)

1 aa507 aa
HAMP: 210-259 aaHAMPHis_kinase: 295-372 aaHis_kinaseHATPase_c: 394-498 aaHATPase_c
HAMPHis_kinaseHATPase_c
  • Simplified architecture: HAMP + His_kinase + HATPase_c
  • Raw architecture: HAMP[210-259] | His_kinase[295-372] | HATPase_c[394-498]
  • Domain count: 3
  • Matched identifier: HKOC_1440472
  • Positioned domains: HAMP 210-259 ; His_kinase 295-372 ; HATPase_c 394-498
Cluster members and taxonomy
Visualization

Representative gene: GCF_000166035#HMPREF9436_RS00400

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 748 224 · GCF_000166035
AssemblyASM16603v1 · Scaffoldhaploid
Genome composition2 928 734 bp · 56,5% GCFaecalibacterium cf. prausnitzii KLE1255
Signal transduction countsGenes 48 · HK 21 · RR 25CheA 0 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyOscillospiraceaeGenusFaecalibacterium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Oscillospiraceae7Faecalibacterium

Related genes

Preview from the same derived genome key