Gene detail

HMPREF9436_RS00995

Histidine kinase, Classic

Faecalibacterium cf. prausnitzii KLE1255 · GCF_000166035

ClassHKTypeClassicLength508 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000166035#HMPREF9436_RS00995Stable P2CS identifier used across views.
GenomeGCF_000166035Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae; Faecalibacterium
Selected clusterHKOC_1436668Run 6 · 1 sequences · id 100% · cov 80% · representative
External referencesWP_005937705.1 · E2ZF15 · MIST4 HMPREF9436_RS00995RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length508 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage241 / 508 aa (47.4%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa508 aa
HAMP: 204-271 aa (68 aa)1HisKA: 275-342 aa (68 aa)2HATPase_c: 388-492 aa (105 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
204-271 aa · 68 aa · 13.4% of protein
Raw tokenHAMP:204:0.00000000000000227:271:68:69
2 HisKA#2
275-342 aa · 68 aa · 13.4% of protein
Raw tokenHisKA:275:4.55e-16:342:68:64
3 HATPase_c#3
388-492 aa · 105 aa · 20.7% of protein
Raw tokenHATPase_c:388:3.11e-27:492:105:109
  • Raw architecture: HAMP:204:0.00000000000000227:271:68:69#HisKA:275:4.55e-16:342:68:64#HATPase_c:388:3.11e-27:492:105:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000166035::NZ_GL538236.1::G00002
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span30035-32266Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9436_00244RefSeq proteinWP_005937705.1
Context group IDGCF_000166035::NZ_GL538236.1::G00002
Context members
HMPREF9436_RS00990HMPREF9436_RS00995
Partner locus tags
HMPREF9436_RS00990HMPREF9436_RS00995
Partner old locus tags
HMPREF9436_00243HMPREF9436_00244
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_005937705.1Primary protein accession used for annex mappings.
UniProt accessionE2ZF15Primary UniProt accession resolved in the annex database.
UniProt IDE2ZF15_9FIRMDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF9436_RS00995Primary locus identifier stored in the genes table.
Old locus tagHMPREF9436_00244Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GL538236.1Sequence record reported by the local genomic context database.
Genomic interval30 740-32 266 nt1 527 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span30 035-32 266 ntGCF_000166035::NZ_GL538236.1::G00002

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000166035::NZ_GL538236.1::G00002

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GL538236.1All displayed genes belong to this local TCS context.
Neighborhood span30 035-32 266 nt2 232 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
30 035 nt32 266 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

HMPREF9436_RS00990GCF_000166035#HMPREF9436_RS00990
RROmpR

30 035-30 721 nt · Forward (+)

Old locus HMPREF9436_00243RefSeq WP_044953253.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1436668Run 6 · HK · 1 sequences
Representative sequenceGCF_000166035#HMPREF9436_RS00995The current gene is the representative for this cluster.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1436668

Simplified PFAM architecture for HKOC_1436668

PFAM domain coverage: 221 / 508 aa (43.5%)

1 aa508 aa
HAMP: 223-270 aaHAMPHisKA: 276-342 aaHisKAHATPase_c: 389-494 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[223-270] | HisKA[276-342] | HATPase_c[389-494]
  • Domain count: 3
  • Matched identifier: HKOC_1436668
  • Positioned domains: HAMP 223-270 ; HisKA 276-342 ; HATPase_c 389-494
Cluster members and taxonomy
Visualization

Representative gene: GCF_000166035#HMPREF9436_RS00995

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 748 224 · GCF_000166035
AssemblyASM16603v1 · Scaffoldhaploid
Genome composition2 928 734 bp · 56,5% GCFaecalibacterium cf. prausnitzii KLE1255
Signal transduction countsGenes 48 · HK 21 · RR 25CheA 0 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyOscillospiraceaeGenusFaecalibacterium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Oscillospiraceae7Faecalibacterium

Related genes

Preview from the same derived genome key