1 HAMP#1
274-343 aa · 70 aa · 12.2% of protein
Raw token
HAMP:274:0.0000164:343:70:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
NE546_RS10995
Histidine kinase, Classic
Neglectibacter timonensis · GCF_024460865
ClassHKTypeClassicLength572 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_024460865#NE546_RS10995Stable P2CS identifier used across views.
GenomeGCF_024460865Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae; Neglectibacter
Domain signature
Compact overview inferred from the domain field
HAMPHis_kinaseHATPase_c
Protein length572 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage246 / 572 aa (43.0%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa572 aa
Domain-by-domain annotation3 items
2 His_kinase#2
359-431 aa · 73 aa · 12.8% of protein
Raw token
His_kinase:359:1e-21:431:73:803 HATPase_c#3
456-558 aa · 103 aa · 18.0% of protein
Raw token
HATPase_c:456:0.0000000105:558:108:109- Raw architecture: HAMP:274:0.0000164:343:70:69#His_kinase:359:1e-21:431:73:80#HATPase_c:456:0.0000000105:558:108:109
- Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_024460865::NZ_JANFZG010000023.1::G00025
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span4996-8302Genomic interval covered by the local TCS group.
Identifiers
Old locus tagNE546_10995RefSeq proteinWP_256294341.1
Context group ID
GCF_024460865::NZ_JANFZG010000023.1::G00025Context members
NE546_RS10995NE546_RS11000
Partner locus tags
NE546_RS10995NE546_RS11000
Partner old locus tags
NE546_10995NE546_11000
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_256294341.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagNE546_RS10995Primary locus identifier stored in the genes table.
Old locus tagNE546_10995Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JANFZG010000023.1Sequence record reported by the local genomic context database.
Genomic interval4 996-6 714 nt1 719 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span4 996-8 302 ntGCF_024460865::NZ_JANFZG010000023.1::G00025
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_024460865::NZ_JANFZG010000023.1::G00025Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JANFZG010000023.1All displayed genes belong to this local TCS context.
Neighborhood span4 996-8 302 nt3 307 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
4 996 nt8 302 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
NE546_RS10995GCF_024460865#NE546_RS10995
HKClassicCurrent focus
4 996-6 714 nt · Forward (+)
NE546_RS11000GCF_024460865#NE546_RS11000
RRunclassified
6 695-8 302 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_024460865#NE546_RS10995The current gene is the representative for this cluster.
PFAM architectureHis_kinase + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1204900
Simplified PFAM architecture for HKOC_1204900
PFAM domain coverage: 177 / 572 aa (30.9%)
1 aa572 aa
His_kinaseHATPase_c
- Simplified architecture: His_kinase + HATPase_c
- Raw architecture: His_kinase[359-431] | HATPase_c[455-558]
- Domain count: 2
- Matched identifier: HKOC_1204900
- Positioned domains: His_kinase 359-431 ; HATPase_c 455-558
Cluster members and taxonomy
Representative gene: GCF_024460865#NE546_RS10995
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 776 382 · GCF_024460865
AssemblyASM2446086v1 · Contighaploid
Genome composition4 030 546 bp · 52,5% GCNeglectibacter timonensis
Signal transduction countsGenes 113 · HK 57 · RR 53CheA 0 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyOscillospiraceaeGenusNeglectibacter
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Oscillospiraceae7Neglectibacter
Related genes
Preview from the same derived genome key