Gene detail

NE546_RS01235

Histidine kinase, Classic

Neglectibacter timonensis · GCF_024460865

ClassHKTypeClassicLength547 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_024460865#NE546_RS01235Stable P2CS identifier used across views.
GenomeGCF_024460865Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae; Neglectibacter
Selected clusterHKOC_1302744Run 6 · 6 sequences · id 100% · cov 80% · representative
External referencesWP_066863671.1 · A0ABT1RVJ7 · MIST4 NE546_RS01235RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHis_kinaseHATPase_c
Protein length547 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage215 / 547 aa (39.3%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa547 aa
HAMP: 244-314 aa (71 aa)1His_kinase: 329-399 aa (71 aa)2HATPase_c: 430-502 aa (73 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
244-314 aa · 71 aa · 13.0% of protein
Raw tokenHAMP:244:0.00000000000291:314:71:69
2 His_kinase#2
329-399 aa · 71 aa · 13.0% of protein
Raw tokenHis_kinase:329:1.97e-19:399:71:80
3 HATPase_c#3
430-502 aa · 73 aa · 13.3% of protein
Raw tokenHATPase_c:430:0.0000000865:502:75:109
  • Raw architecture: HAMP:244:0.00000000000291:314:71:69#His_kinase:329:1.97e-19:399:71:80#HATPase_c:430:0.0000000865:502:75:109
  • Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_024460865::NZ_JANFZG010000002.1::G00019
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span78902-81788Genomic interval covered by the local TCS group.
Identifiers
Old locus tagNE546_01235RefSeq proteinWP_066863671.1
Context group IDGCF_024460865::NZ_JANFZG010000002.1::G00019
Context members
NE546_RS01235NE546_RS01240
Partner locus tags
NE546_RS01235NE546_RS01240
Partner old locus tags
NE546_01235NE546_01240
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_066863671.1Primary protein accession used for annex mappings.
UniProt accessionA0ABT1RVJ7Primary UniProt accession resolved in the annex database.
UniProt IDA0ABT1RVJ7_9FIRMDisplay identifier provided by UniProt.
GO / PubMed1 / 0Unique GO terms and literature references available below.
GO terms

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagNE546_RS01235Primary locus identifier stored in the genes table.
Old locus tagNE546_01235Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JANFZG010000002.1Sequence record reported by the local genomic context database.
Genomic interval78 902-80 545 nt1 644 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span78 902-81 788 ntGCF_024460865::NZ_JANFZG010000002.1::G00019

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_024460865::NZ_JANFZG010000002.1::G00019

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JANFZG010000002.1All displayed genes belong to this local TCS context.
Neighborhood span78 902-81 788 nt2 887 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
78 902 nt81 788 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

NE546_RS01235GCF_024460865#NE546_RS01235
HKClassicCurrent focus

78 902-80 545 nt · Forward (+)

Old locus NE546_01235RefSeq WP_066863671.1
NE546_RS01240GCF_024460865#NE546_RS01240
RRunclassified

80 523-81 788 nt · Forward (+)

Old locus NE546_01240RefSeq WP_256191431.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1302744Run 6 · HK · 6 sequences
Representative sequenceGCF_024460865#NE546_RS01235The current gene is the representative for this cluster.
PFAM architectureHAMP + His_kinase + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1302744

Simplified PFAM architecture for HKOC_1302744

PFAM domain coverage: 197 / 547 aa (36.0%)

1 aa547 aa
HAMP: 262-312 aaHAMPHis_kinase: 329-400 aaHis_kinaseHATPase_c: 429-502 aaHATPase_c
HAMPHis_kinaseHATPase_c
  • Simplified architecture: HAMP + His_kinase + HATPase_c
  • Raw architecture: HAMP[262-312] | His_kinase[329-400] | HATPase_c[429-502]
  • Domain count: 3
  • Matched identifier: HKOC_1302744
  • Positioned domains: HAMP 262-312 ; His_kinase 329-400 ; HATPase_c 429-502
Cluster members and taxonomy
Visualization

Representative gene: GCF_024460865#NE546_RS01235

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 776 382 · GCF_024460865
AssemblyASM2446086v1 · Contighaploid
Genome composition4 030 546 bp · 52,5% GCNeglectibacter timonensis
Signal transduction countsGenes 113 · HK 57 · RR 53CheA 0 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyOscillospiraceaeGenusNeglectibacter
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Oscillospiraceae7Neglectibacter

Related genes

Preview from the same derived genome key