Gene detail

NE546_RS07975

Histidine kinase, Classic

Neglectibacter timonensis · GCF_024460865

ClassHKTypeClassicLength598 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_024460865#NE546_RS07975Stable P2CS identifier used across views.
GenomeGCF_024460865Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae; Neglectibacter
Selected clusterHKOC_0993813Run 6 · 6 sequences · id 100% · cov 80%
External referencesWP_066862760.1 · A0ABT1RYU2 · MIST4 NE546_RS07975RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHis_kinaseHATPase_c
Protein length598 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage258 / 598 aa (43.1%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa598 aa
HAMP: 301-370 aa (70 aa)1His_kinase: 386-462 aa (77 aa)2HATPase_c: 485-595 aa (111 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
301-370 aa · 70 aa · 11.7% of protein
Raw tokenHAMP:301:0.00000000241:370:70:69
2 His_kinase#2
386-462 aa · 77 aa · 12.9% of protein
Raw tokenHis_kinase:386:4.93e-30:462:77:80
3 HATPase_c#3
485-595 aa · 111 aa · 18.6% of protein
Raw tokenHATPase_c:485:0.0000000000426:595:111:109
  • Raw architecture: HAMP:301:0.00000000241:370:70:69#His_kinase:386:4.93e-30:462:77:80#HATPase_c:485:0.0000000000426:595:111:109
  • Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_024460865::NZ_JANFZG010000014.1::G00009
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span40997-44326Genomic interval covered by the local TCS group.
Identifiers
Old locus tagNE546_07975RefSeq proteinWP_066862760.1
Context group IDGCF_024460865::NZ_JANFZG010000014.1::G00009
Context members
NE546_RS07975NE546_RS07980
Partner locus tags
NE546_RS07975NE546_RS07980
Partner old locus tags
NE546_07975NE546_07980
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_066862760.1Primary protein accession used for annex mappings.
UniProt accessionA0ABT1RYU2Primary UniProt accession resolved in the annex database.
UniProt IDA0ABT1RYU2_9FIRMDisplay identifier provided by UniProt.
GO / PubMed1 / 0Unique GO terms and literature references available below.
GO terms

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagNE546_RS07975Primary locus identifier stored in the genes table.
Old locus tagNE546_07975Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JANFZG010000014.1Sequence record reported by the local genomic context database.
Genomic interval40 997-42 793 nt1 797 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span40 997-44 326 ntGCF_024460865::NZ_JANFZG010000014.1::G00009

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_024460865::NZ_JANFZG010000014.1::G00009

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JANFZG010000014.1All displayed genes belong to this local TCS context.
Neighborhood span40 997-44 326 nt3 330 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
40 997 nt44 326 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

NE546_RS07975GCF_024460865#NE546_RS07975
HKClassicCurrent focus

40 997-42 793 nt · Forward (+)

Old locus NE546_07975RefSeq WP_066862760.1
NE546_RS07980GCF_024460865#NE546_RS07980
RRunclassified

42 869-44 326 nt · Forward (+)

Old locus NE546_07980RefSeq WP_066862762.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0993813Run 6 · HK · 6 sequences
Representative sequenceGCF_937966475#QMD54_RS09210Use this link to inspect the representative gene detail.
PFAM architectureHAMP + His_kinase + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0993813

Simplified PFAM architecture for HKOC_0993813

PFAM domain coverage: 228 / 614 aa (37.1%)

1 aa614 aa
HAMP: 346-386 aaHAMPHis_kinase: 403-478 aaHis_kinaseHATPase_c: 501-611 aaHATPase_c
HAMPHis_kinaseHATPase_c
  • Simplified architecture: HAMP + His_kinase + HATPase_c
  • Raw architecture: HAMP[346-386] | His_kinase[403-478] | HATPase_c[501-611]
  • Domain count: 3
  • Matched identifier: HKOC_0993813
  • Positioned domains: HAMP 346-386 ; His_kinase 403-478 ; HATPase_c 501-611
Cluster members and taxonomy
Visualization

Representative gene: GCF_937966475#QMD54_RS09210

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 776 382 · GCF_024460865
AssemblyASM2446086v1 · Contighaploid
Genome composition4 030 546 bp · 52,5% GCNeglectibacter timonensis
Signal transduction countsGenes 113 · HK 57 · RR 53CheA 0 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyOscillospiraceaeGenusNeglectibacter
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Oscillospiraceae7Neglectibacter

Related genes

Preview from the same derived genome key