1 dCache_1#1
75-223 aa · 149 aa · 25.6% of protein
Raw token
dCache_1:75:0.0000000883:223:156:195P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
NE546_RS04405
Histidine kinase, Classic
Neglectibacter timonensis · GCF_024460865
ClassHKTypeClassicLength581 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_024460865#NE546_RS04405Stable P2CS identifier used across views.
GenomeGCF_024460865Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae; Neglectibacter
Domain signature
Compact overview inferred from the domain field
dCache_1HAMPHis_kinaseHATPase_c
Protein length581 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage401 / 581 aa (69.0%)Merged over positioned domains only.
Domain description1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa581 aa
Domain-by-domain annotation4 items
2 HAMP#2
286-353 aa · 68 aa · 11.7% of protein
Raw token
HAMP:286:0.00000063:353:68:693 His_kinase#3
375-453 aa · 79 aa · 13.6% of protein
Raw token
His_kinase:375:9.32e-32:453:79:804 HATPase_c#4
473-577 aa · 105 aa · 18.1% of protein
Raw token
HATPase_c:473:2.13e-18:577:107:109- Raw architecture: dCache_1:75:0.0000000883:223:156:195#HAMP:286:0.00000063:353:68:69#His_kinase:375:9.32e-32:453:79:80#HATPase_c:473:2.13e-18:577:107:109
- Domain description: 1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_024460865::NZ_JANFZG010000007.1::G00054
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span15383-17855Genomic interval covered by the local TCS group.
Identifiers
Old locus tagNE546_04400RefSeq proteinWP_066862040.1
Context group ID
GCF_024460865::NZ_JANFZG010000007.1::G00054Context members
NE546_RS04405NE546_RS04410
Partner locus tags
NE546_RS04405NE546_RS04410
Partner old locus tags
NE546_04400NE546_04405
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_066862040.1Primary protein accession used for annex mappings.
UniProt accessionA0ABT1RWF2Primary UniProt accession resolved in the annex database.
UniProt IDA0ABT1RWF2_9FIRMDisplay identifier provided by UniProt.
GO / PubMed1 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagNE546_RS04405Primary locus identifier stored in the genes table.
Old locus tagNE546_04400Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JANFZG010000007.1Sequence record reported by the local genomic context database.
Genomic interval15 383-17 128 nt1 746 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span15 383-17 855 ntGCF_024460865::NZ_JANFZG010000007.1::G00054
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_024460865::NZ_JANFZG010000007.1::G00054Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JANFZG010000007.1All displayed genes belong to this local TCS context.
Neighborhood span15 383-17 855 nt2 473 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
15 383 nt17 855 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
NE546_RS04405GCF_024460865#NE546_RS04405
HKClassicCurrent focus
15 383-17 128 nt · Forward (+)
NE546_RS04410GCF_024460865#NE546_RS04410
RRunclassified
17 106-17 855 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_024460865#NE546_RS04405The current gene is the representative for this cluster.
PFAM architectureHis_kinase + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1159397
Simplified PFAM architecture for HKOC_1159397
PFAM domain coverage: 184 / 581 aa (31.7%)
1 aa581 aa
His_kinaseHATPase_c
- Simplified architecture: His_kinase + HATPase_c
- Raw architecture: His_kinase[375-453] | HATPase_c[474-578]
- Domain count: 2
- Matched identifier: HKOC_1159397
- Positioned domains: His_kinase 375-453 ; HATPase_c 474-578
Cluster members and taxonomy
Representative gene: GCF_024460865#NE546_RS04405
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 776 382 · GCF_024460865
AssemblyASM2446086v1 · Contighaploid
Genome composition4 030 546 bp · 52,5% GCNeglectibacter timonensis
Signal transduction countsGenes 113 · HK 57 · RR 53CheA 0 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyOscillospiraceaeGenusNeglectibacter
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Oscillospiraceae7Neglectibacter
Related genes
Preview from the same derived genome key