Gene detail

NE546_RS01740

Histidine kinase, Classic

Neglectibacter timonensis · GCF_024460865

ClassHKTypeClassicLength567 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_024460865#NE546_RS01740Stable P2CS identifier used across views.
GenomeGCF_024460865Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae; Neglectibacter
Selected clusterHKOC_1227325Run 6 · 2 sequences · id 100% · cov 80% · representative
External referencesWP_256191811.1 · A0ABT1RZN8 · MIST4 NE546_RS01740RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

dCache_1HAMPHis_kinaseHATPase_c
Protein length567 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage445 / 567 aa (78.5%)Merged over positioned domains only.
Domain description1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa567 aa
dCache_1: 33-214 aa (182 aa)1HAMP: 260-329 aa (70 aa)2His_kinase: 353-429 aa (77 aa)3HATPase_c: 441-556 aa (116 aa)4
Domain-by-domain annotation4 items
1 dCache_1#1
33-214 aa · 182 aa · 32.1% of protein
Raw tokendCache_1:33:0.000000837:214:182:195
2 HAMP#2
260-329 aa · 70 aa · 12.3% of protein
Raw tokenHAMP:260:0.000000775:329:70:69
3 His_kinase#3
353-429 aa · 77 aa · 13.6% of protein
Raw tokenHis_kinase:353:4.84e-21:429:78:80
4 HATPase_c#4
441-556 aa · 116 aa · 20.5% of protein
Raw tokenHATPase_c:441:0.0000074:556:117:109
  • Raw architecture: dCache_1:33:0.000000837:214:182:195#HAMP:260:0.000000775:329:70:69#His_kinase:353:4.84e-21:429:78:80#HATPase_c:441:0.0000074:556:117:109
  • Domain description: 1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_024460865::NZ_JANFZG010000003.1::G00029
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span23608-26063Genomic interval covered by the local TCS group.
Identifiers
Old locus tagNE546_01735RefSeq proteinWP_256191811.1
Context group IDGCF_024460865::NZ_JANFZG010000003.1::G00029
Context members
NE546_RS01740NE546_RS01745
Partner locus tags
NE546_RS01740NE546_RS01745
Partner old locus tags
NE546_01735NE546_01740
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_256191811.1Primary protein accession used for annex mappings.
UniProt accessionA0ABT1RZN8Primary UniProt accession resolved in the annex database.
UniProt IDA0ABT1RZN8_9FIRMDisplay identifier provided by UniProt.
GO / PubMed1 / 0Unique GO terms and literature references available below.
GO terms

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagNE546_RS01740Primary locus identifier stored in the genes table.
Old locus tagNE546_01735Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JANFZG010000003.1Sequence record reported by the local genomic context database.
Genomic interval23 608-25 311 nt1 704 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span23 608-26 063 ntGCF_024460865::NZ_JANFZG010000003.1::G00029

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_024460865::NZ_JANFZG010000003.1::G00029

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JANFZG010000003.1All displayed genes belong to this local TCS context.
Neighborhood span23 608-26 063 nt2 456 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
23 608 nt26 063 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

NE546_RS01740GCF_024460865#NE546_RS01740
HKClassicCurrent focus

23 608-25 311 nt · Reverse (-)

Old locus NE546_01735RefSeq WP_256191811.1
NE546_RS01745GCF_024460865#NE546_RS01745
RRunclassified

25 308-26 063 nt · Reverse (-)

Old locus NE546_01740RefSeq WP_066866996.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1227325Run 6 · HK · 2 sequences
Representative sequenceGCF_024460865#NE546_RS01740The current gene is the representative for this cluster.
PFAM architectureHis_kinase1 domain in the representative PFAM annotation.

PFAM architecture for HKOC_1227325

Simplified PFAM architecture for HKOC_1227325

PFAM domain coverage: 76 / 567 aa (13.4%)

1 aa567 aa
His_kinase: 353-428 aaHis_kinase
His_kinase
  • Simplified architecture: His_kinase
  • Raw architecture: His_kinase[353-428]
  • Domain count: 1
  • Matched identifier: HKOC_1227325
  • Positioned domains: His_kinase 353-428
Cluster members and taxonomy
Visualization

Representative gene: GCF_024460865#NE546_RS01740

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 776 382 · GCF_024460865
AssemblyASM2446086v1 · Contighaploid
Genome composition4 030 546 bp · 52,5% GCNeglectibacter timonensis
Signal transduction countsGenes 113 · HK 57 · RR 53CheA 0 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyOscillospiraceaeGenusNeglectibacter
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Oscillospiraceae7Neglectibacter

Related genes

Preview from the same derived genome key