Gene detail

DW085_RS05250

Histidine kinase, Classic

Clostridium sp. AF50-3 · GCF_003477445

ClassHKTypeClassicLength529 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003477445#DW085_RS05250Stable P2CS identifier used across views.
GenomeGCF_003477445Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Clostridiaceae; Clostridium
Selected clusterHKOC_1360507Run 6 · 3 sequences · id 100% · cov 80% · representative
External referencesWP_118481905.1 · MIST4 DW085_RS05250RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHis_kinaseHATPase_c
Protein length529 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage260 / 529 aa (49.1%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for DW085_RS05250
Domain-by-domain annotation3 items
1 HAMP#1
235-303 aa · 69 aa · 13.0% of protein
Raw tokenHAMP:235:0.00000000000000139:303:69:69
2 His_kinase#2
318-397 aa · 80 aa · 15.1% of protein
Raw tokenHis_kinase:318:1.87e-31:397:80:80
3 HATPase_c#3
413-523 aa · 111 aa · 21.0% of protein
Raw tokenHATPase_c:413:0.000000000000903:523:111:109
  • Raw architecture: HAMP:235:0.00000000000000139:303:69:69#His_kinase:318:1.87e-31:397:80:80#HATPase_c:413:0.000000000000903:523:111:109
  • Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_003477445::NZ_QUDH01000003.1::G00014
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span200243-203142Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDW085_05245RefSeq proteinWP_118481905.1
Context group IDGCF_003477445::NZ_QUDH01000003.1::G00014
Context members
DW085_RS05250DW085_RS05255
Partner locus tags
DW085_RS05250DW085_RS05255
Partner old locus tags
DW085_05245DW085_05250
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_118481905.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagDW085_RS05250Primary locus identifier stored in the genes table.
Old locus tagDW085_05245Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_QUDH01000003.1Sequence record reported by the local genomic context database.
Genomic interval200 243-201 832 nt1 590 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span200 243-203 142 ntGCF_003477445::NZ_QUDH01000003.1::G00014

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_003477445::NZ_QUDH01000003.1::G00014

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_QUDH01000003.1All displayed genes belong to this local TCS context.
Neighborhood span200 243-203 142 nt2 900 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
200 243 nt203 142 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

DW085_RS05250GCF_003477445#DW085_RS05250
HKClassicCurrent focus

200 243-201 832 nt · Reverse (-)

Old locus DW085_05245RefSeq WP_118481905.1
DW085_RS05255GCF_003477445#DW085_RS05255
RRunclassified

202 027-203 142 nt · Reverse (-)

Old locus DW085_05250RefSeq WP_118491663.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1360507Run 6 · HK · 3 sequences
Representative sequenceGCF_003477445#DW085_RS05250The current gene is the representative for this cluster.
PFAM architectureHAMP + His_kinase + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1360507

Simplified PFAM architecture for HKOC_1360507

PFAM domain coverage: 239 / 529 aa (45.2%)

1 aa529 aa
HAMP: 252-302 aaHAMPHis_kinase: 319-395 aaHis_kinaseHATPase_c: 413-523 aaHATPase_c
HAMPHis_kinaseHATPase_c
  • Simplified architecture: HAMP + His_kinase + HATPase_c
  • Raw architecture: HAMP[252-302] | His_kinase[319-395] | HATPase_c[413-523]
  • Domain count: 3
  • Matched identifier: HKOC_1360507
  • Positioned domains: HAMP 252-302 ; His_kinase 319-395 ; HATPase_c 413-523
Cluster members and taxonomy
Visualization

Representative gene: GCF_003477445#DW085_RS05250

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 2 293 021 · GCF_003477445
AssemblyASM347744v1 · Scaffoldhaploid
Genome composition3 864 962 bp · 48,0% GCClostridium sp. AF50-3
Signal transduction countsGenes 53 · HK 28 · RR 22CheA 0 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyClostridiaceaeGenusClostridium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Clostridiaceae7Clostridium

Related genes

Preview from the same derived genome key