1 Response_reg#1
6-108 aa · 103 aa · 29.5% of protein
Raw token
Response_reg:6:8.64e-27:108:105:111P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
FN517_RS12095
Response regulator, CheB family
Escherichia coli · GCF_902164025
ClassRRTypeCheBLength349 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_902164025#FN517_RS12095Stable P2CS identifier used across views.
GenomeGCF_902164025Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Domain signature
Compact overview inferred from the domain field
Response_regCheB_methylest
Protein length349 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage282 / 349 aa (80.8%)Merged over positioned domains only.
Domain description1 Response_reg,1 CheB_methylestSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa349 aa
Domain-by-domain annotation2 items
2 CheB_methylest#2
159-337 aa · 179 aa · 51.3% of protein
Raw token
CheB_methylest:159:3.05e-91:337:180:177- Raw architecture: Response_reg:6:8.64e-27:108:105:111#CheB_methylest:159:3.05e-91:337:180:177
- Domain description: 1 Response_reg,1 CheB_methylest
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_902164025::NZ_CABHBW010000006.1::G00026
Group size22 locus tags listed below.
HK / RR0 / 2Counts resolved for the local TCS neighborhood.
Context span117100-118553Genomic interval covered by the local TCS group.
Identifiers
Context group ID
GCF_902164025::NZ_CABHBW010000006.1::G00026Context members
FN517_RS12095FN517_RS12100
Partner locus tags
FN517_RS12095FN517_RS12100
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_000036385.1Primary protein accession used for annex mappings.
UniProt accessionB7MVV1Primary UniProt accession resolved in the annex database.
UniProt IDB7MVV1_ECO81Display identifier provided by UniProt.
GO / PubMed5 / 1Unique GO terms and literature references available below.
Reference hubs
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagFN517_RS12095Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_CABHBW010000006.1Sequence record reported by the local genomic context database.
Genomic interval117 100-118 149 nt1 050 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span117 100-118 553 ntGCF_902164025::NZ_CABHBW010000006.1::G00026
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_902164025::NZ_CABHBW010000006.1::G00026Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CABHBW010000006.1All displayed genes belong to this local TCS context.
Neighborhood span117 100-118 553 nt1 454 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
117 100 nt118 553 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
FN517_RS12095GCF_902164025#FN517_RS12095
RRCheBCurrent focus
117 100-118 149 nt · Forward (+)
FN517_RS12100GCF_902164025#FN517_RS12100
RRCheY
118 164-118 553 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000010485#ECSF_RS09250Use this link to inspect the representative gene detail.
PFAM architectureResponse_reg + CheB_methylest2 domains in the representative PFAM annotation.
PFAM architecture for RROC_0481957
Simplified PFAM architecture for RROC_0481957
PFAM domain coverage: 281 / 349 aa (80.5%)
1 aa349 aa
Response_regCheB_methylest
- Simplified architecture: Response_reg + CheB_methylest
- Raw architecture: Response_reg[6-108] | CheB_methylest[159-336]
- Domain count: 2
- Matched identifier: RROC_0481957
- Positioned domains: Response_reg 6-108 ; Response_reg 6-108 ; CheB_methylest 159-336 ; CheB_methylest 159-336
Cluster members and taxonomy
Representative gene: GCF_000010485#ECSF_RS09250
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 562 · GCF_902164025
Assembly25964_2#194 · Scaffoldhaploid
Genome composition5 252 367 bp · 50,0% GCEscherichia coli
Signal transduction countsGenes 66 · HK 32 · RR 34CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia
Related genes
Preview from the same derived genome key