Gene detail

FN517_RS01635

Response regulator, unclassified

Escherichia coli · GCF_902164025

ClassRRTypePrrALength461 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_902164025#FN517_RS01635Stable P2CS identifier used across views.
GenomeGCF_902164025Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Selected clusterRROC_0236037Run 7 · 3177 sequences · id 100% · cov 80%
External referencesWP_000125287.1 · F4T034 · MIST4 FN517_RS01635RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

Response_regAAAHTH_8
Protein length461 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage295 / 461 aa (64.0%)Merged over positioned domains only.
Domain description1 Response_reg,1 AAA,1 HTH_8Summary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa461 aa
Response_reg: 7-112 aa (106 aa)1AAA: 169-319 aa (151 aa)2HTH_8: 417-454 aa (38 aa)3
Domain-by-domain annotation3 items
1 Response_reg#1
7-112 aa · 106 aa · 23.0% of protein
Raw tokenResponse_reg:7:2.3e-35:112:106:111
2 AAA#2
169-319 aa · 151 aa · 32.8% of protein
Raw tokenAAA:169:0.00000000168:319:165:130
3 HTH_8#3
417-454 aa · 38 aa · 8.2% of protein
Raw tokenHTH_8:417:0.000000000000134:454:38:40
  • Raw architecture: Response_reg:7:2.3e-35:112:106:111#AAA:169:0.00000000168:319:165:130#HTH_8:417:0.000000000000134:454:38:40
  • Domain description: 1 Response_reg,1 AAA,1 HTH_8
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_902164025::NZ_CABHBW010000001.1::G00006
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span366987-370195Genomic interval covered by the local TCS group.
Context group IDGCF_902164025::NZ_CABHBW010000001.1::G00006
Context members
FN517_RS01635FN517_RS01640
Partner locus tags
FN517_RS01635FN517_RS01640
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_000125287.1Primary protein accession used for annex mappings.
UniProt accessionF4T034Primary UniProt accession resolved in the annex database.
UniProt IDF4T034_ECOLXDisplay identifier provided by UniProt.
GO / PubMed5 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagFN517_RS01635Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_CABHBW010000001.1Sequence record reported by the local genomic context database.
Genomic interval366 987-368 372 nt1 386 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span366 987-370 195 ntGCF_902164025::NZ_CABHBW010000001.1::G00006

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_902164025::NZ_CABHBW010000001.1::G00006

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CABHBW010000001.1All displayed genes belong to this local TCS context.
Neighborhood span366 987-370 195 nt3 209 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
366 987 nt370 195 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

FN517_RS01640GCF_902164025#FN517_RS01640
HKClassic

368 369-370 195 nt · Reverse (-)

RefSeq WP_001296244.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterRROC_0236037Run 7 · RR · 3177 sequences
Representative sequenceGCF_000010485#ECSF_RS11245Use this link to inspect the representative gene detail.
PFAM architectureResponse_reg + Sigma54_activat + AAA_lid_14 + HTH_84 domains in the representative PFAM annotation.

PFAM architecture for RROC_0236037

Simplified PFAM architecture for RROC_0236037

PFAM domain coverage: 393 / 461 aa (85.2%)

1 aa461 aa
Response_reg: 7-115 aaResponse_regResponse_reg: 7-115 aaResponse_regSigma54_activat: 145-311 aaSigma54_activatSigma54_activat: 145-311 aaSigma54_activatAAA_lid_14: 317-393 aaAAA_lid_14AAA_lid_14: 317-393 aaAAA_lid_14HTH_8: 415-454 aaHTH_8HTH_8: 415-454 aaHTH_8
Response_regSigma54_activatAAA_lid_14HTH_8
  • Simplified architecture: Response_reg + Sigma54_activat + AAA_lid_14 + HTH_8
  • Raw architecture: Response_reg[7-115] | Sigma54_activat[145-311] | AAA_lid_14[317-393] | HTH_8[415-454]
  • Domain count: 4
  • Matched identifier: RROC_0236037
  • Positioned domains: Response_reg 7-115 ; Response_reg 7-115 ; Sigma54_activat 145-311 ; Sigma54_activat 145-311 ; AAA_lid_14 317-393 ; AAA_lid_14 317-393 ; HTH_8 415-454 ; HTH_8 415-454
Cluster members and taxonomy
Visualization

Representative gene: GCF_000010485#ECSF_RS11245

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 562 · GCF_902164025
Assembly25964_2#194 · Scaffoldhaploid
Genome composition5 252 367 bp · 50,0% GCEscherichia coli
Signal transduction countsGenes 66 · HK 32 · RR 34CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia

Related genes

Preview from the same derived genome key