1 GAF#1
226-347 aa · 122 aa · 21.6% of protein
Raw token
GAF:226:0.0000279:347:134:133P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
FN517_RS00930
Histidine kinase, Classic
Escherichia coli · GCF_902164025
ClassHKTypeClassicLength565 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_902164025#FN517_RS00930Stable P2CS identifier used across views.
GenomeGCF_902164025Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Domain signature
Compact overview inferred from the domain field
GAFHis_kinaseHATPase_c
Protein length565 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage298 / 565 aa (52.7%)Merged over positioned domains only.
Domain description1 GAF,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa565 aa
Domain-by-domain annotation3 items
2 His_kinase#2
359-438 aa · 80 aa · 14.2% of protein
Raw token
His_kinase:359:1.12e-31:438:81:803 HATPase_c#3
456-551 aa · 96 aa · 17.0% of protein
Raw token
HATPase_c:456:0.0000000000374:551:103:109- Raw architecture: GAF:226:0.0000279:347:134:133#His_kinase:359:1.12e-31:438:81:80#HATPase_c:456:0.0000000000374:551:103:109
- Domain description: 1 GAF,1 His_kinase,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_902164025::NZ_CABHBW010000001.1::G00004
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span205171-207617Genomic interval covered by the local TCS group.
Identifiers
Context group ID
GCF_902164025::NZ_CABHBW010000001.1::G00004Context members
FN517_RS00925FN517_RS00930
Partner locus tags
FN517_RS00925FN517_RS00930
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_000544377.1Primary protein accession used for annex mappings.
UniProt accessionB7MXP2Primary UniProt accession resolved in the annex database.
UniProt IDB7MXP2_ECO81Display identifier provided by UniProt.
GO / PubMed4 / 1Unique GO terms and literature references available below.
Reference hubs
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagFN517_RS00930Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_CABHBW010000001.1Sequence record reported by the local genomic context database.
Genomic interval205 920-207 617 nt1 698 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span205 171-207 617 ntGCF_902164025::NZ_CABHBW010000001.1::G00004
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_902164025::NZ_CABHBW010000001.1::G00004Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CABHBW010000001.1All displayed genes belong to this local TCS context.
Neighborhood span205 171-207 617 nt2 447 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
205 171 nt207 617 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
FN517_RS00925GCF_902164025#FN517_RS00925
RRLytTR
205 171-205 905 nt · Reverse (-)
FN517_RS00930GCF_902164025#FN517_RS00930
HKClassicCurrent focus
205 920-207 617 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000007445#C_RS13835Use this link to inspect the representative gene detail.
PFAM architecture5TM-5TMR_LYT + GAF + His_kinase + HATPase_c4 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1234001
Simplified PFAM architecture for HKOC_1234001
PFAM domain coverage: 460 / 565 aa (81.4%)
1 aa565 aa
5TM-5TMR_LYTGAFHis_kinaseHATPase_c
- Simplified architecture: 5TM-5TMR_LYT + GAF + His_kinase + HATPase_c
- Raw architecture: 5TM-5TMR_LYT[28-192] | GAF[227-343] | His_kinase[359-438] | HATPase_c[456-553]
- Domain count: 4
- Matched identifier: HKOC_1234001
- Positioned domains: 5TM-5TMR_LYT 28-192 ; GAF 227-343 ; His_kinase 359-438 ; HATPase_c 456-553
Cluster members and taxonomy
Representative gene: GCF_000007445#C_RS13835
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 562 · GCF_902164025
Assembly25964_2#194 · Scaffoldhaploid
Genome composition5 252 367 bp · 50,0% GCEscherichia coli
Signal transduction countsGenes 66 · HK 32 · RR 34CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia
Related genes
Preview from the same derived genome key