Gene detail

FN517_RS00550

Histidine kinase, Classic

Escherichia coli · GCF_902164025

ClassHKTypeClassicLength566 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_902164025#FN517_RS00550Stable P2CS identifier used across views.
GenomeGCF_902164025Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Selected clusterHKOC_1228913Run 6 · 9180 sequences · id 100% · cov 80%
External referencesWP_001296285.1 · D3H2W0 · MIST4 FN517_RS00550RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

PilJHAMPHisKA_3HATPase_c
Protein length566 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage324 / 566 aa (57.2%)Merged over positioned domains only.
Domain description1 PilJ,1 HAMP,1 HisKA_3,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa566 aa
PilJ: 31-125 aa (95 aa)1HAMP: 150-224 aa (75 aa)2HisKA_3: 361-424 aa (64 aa)3HATPase_c: 467-556 aa (90 aa)4
Domain-by-domain annotation4 items
1 PilJ#1
31-125 aa · 95 aa · 16.8% of protein
Raw tokenPilJ:31:3.53e-17:125:111:112
2 HAMP#2
150-224 aa · 75 aa · 13.3% of protein
Raw tokenHAMP:150:0.00000000000132:224:75:69
3 HisKA_3#3
361-424 aa · 64 aa · 11.3% of protein
Raw tokenHisKA_3:361:2.31e-17:424:64:68
4 HATPase_c#4
467-556 aa · 90 aa · 15.9% of protein
Raw tokenHATPase_c:467:2.11e-19:556:105:109
  • Raw architecture: PilJ:31:3.53e-17:125:111:112#HAMP:150:0.00000000000132:224:75:69#HisKA_3:361:2.31e-17:424:64:68#HATPase_c:467:2.11e-19:556:105:109
  • Domain description: 1 PilJ,1 HAMP,1 HisKA_3,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_902164025::NZ_CABHBW010000001.1::G00003
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span130745-132445Genomic interval covered by the local TCS group.
Context group IDGCF_902164025::NZ_CABHBW010000001.1::G00003
Context members
FN517_RS00550
Partner locus tags
FN517_RS00550
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_001296285.1Primary protein accession used for annex mappings.
UniProt accessionD3H2W0Primary UniProt accession resolved in the annex database.
UniProt IDD3H2W0_ECO44Display identifier provided by UniProt.
GO / PubMed4 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagFN517_RS00550Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_CABHBW010000001.1Sequence record reported by the local genomic context database.
Genomic interval130 745-132 445 nt1 701 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span130 745-132 445 ntGCF_902164025::NZ_CABHBW010000001.1::G00003

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_902164025::NZ_CABHBW010000001.1::G00003

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CABHBW010000001.1All displayed genes belong to this local TCS context.
Neighborhood span130 745-132 445 nt1 701 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
130 745 nt132 445 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1228913Run 6 · HK · 9180 sequences
Representative sequenceGCF_000007445#C_RS14225Use this link to inspect the representative gene detail.
PFAM architecturePilJ + HAMP + HisKA_3 + HATPase_c4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1228913

Simplified PFAM architecture for HKOC_1228913

PFAM domain coverage: 302 / 566 aa (53.4%)

1 aa566 aa
PilJ: 32-127 aaPilJHAMP: 172-223 aaHAMPHisKA_3: 361-424 aaHisKA_3HATPase_c: 467-556 aaHATPase_c
PilJHAMPHisKA_3HATPase_c
  • Simplified architecture: PilJ + HAMP + HisKA_3 + HATPase_c
  • Raw architecture: PilJ[32-127] | HAMP[172-223] | HisKA_3[361-424] | HATPase_c[467-556]
  • Domain count: 4
  • Matched identifier: HKOC_1228913
  • Positioned domains: PilJ 32-127 ; HAMP 172-223 ; HisKA_3 361-424 ; HATPase_c 467-556
Cluster members and taxonomy
Visualization

Representative gene: GCF_000007445#C_RS14225

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 562 · GCF_902164025
Assembly25964_2#194 · Scaffoldhaploid
Genome composition5 252 367 bp · 50,0% GCEscherichia coli
Signal transduction countsGenes 66 · HK 32 · RR 34CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia

Related genes

Preview from the same derived genome key