Gene detail

FN517_RS10285

Histidine kinase, Classic

Escherichia coli · GCF_902164025

ClassHKTypeClassicLength366 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_902164025#FN517_RS10285Stable P2CS identifier used across views.
GenomeGCF_902164025Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Selected clusterHKOC_2711908Run 6 · 6619 sequences · id 100% · cov 80%
External referencesWP_001052123.1 · F4T7G5 · MIST4 FN517_RS10285RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length366 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage235 / 366 aa (64.2%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa366 aa
HAMP: 72-139 aa (68 aa)1HisKA: 147-204 aa (58 aa)2HATPase_c: 252-360 aa (109 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
72-139 aa · 68 aa · 18.6% of protein
Raw tokenHAMP:72:0.00000056:139:68:69
2 HisKA#2
147-204 aa · 58 aa · 15.8% of protein
Raw tokenHisKA:147:0.00000000179:204:61:64
3 HATPase_c#3
252-360 aa · 109 aa · 29.8% of protein
Raw tokenHATPase_c:252:5.91e-22:360:111:109
  • Raw architecture: HAMP:72:0.00000056:139:68:69#HisKA:147:0.00000000179:204:61:64#HATPase_c:252:5.91e-22:360:111:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_902164025::NZ_CABHBW010000005.1::G00021
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span144717-146486Genomic interval covered by the local TCS group.
Context group IDGCF_902164025::NZ_CABHBW010000005.1::G00021
Context members
FN517_RS10285FN517_RS10290
Partner locus tags
FN517_RS10285FN517_RS10290
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_001052123.1Primary protein accession used for annex mappings.
UniProt accessionF4T7G5Primary UniProt accession resolved in the annex database.
UniProt IDF4T7G5_ECOLXDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagFN517_RS10285Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_CABHBW010000005.1Sequence record reported by the local genomic context database.
Genomic interval144 717-145 817 nt1 101 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span144 717-146 486 ntGCF_902164025::NZ_CABHBW010000005.1::G00021

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_902164025::NZ_CABHBW010000005.1::G00021

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CABHBW010000005.1All displayed genes belong to this local TCS context.
Neighborhood span144 717-146 486 nt1 770 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
144 717 nt146 486 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

FN517_RS10290GCF_902164025#FN517_RS10290
RROmpR

145 818-146 486 nt · Reverse (-)

RefSeq WP_000697905.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2711908Run 6 · HK · 6619 sequences
Representative sequenceGCF_000007445#C_RS24210Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2711908

Simplified PFAM architecture for HKOC_2711908

PFAM domain coverage: 215 / 366 aa (58.7%)

1 aa366 aa
HAMP: 91-140 aaHAMPHisKA: 147-203 aaHisKAHATPase_c: 252-359 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[91-140] | HisKA[147-203] | HATPase_c[252-359]
  • Domain count: 3
  • Matched identifier: HKOC_2711908
  • Positioned domains: HAMP 91-140 ; HisKA 147-203 ; HATPase_c 252-359
Cluster members and taxonomy
Visualization

Representative gene: GCF_000007445#C_RS24210

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 562 · GCF_902164025
Assembly25964_2#194 · Scaffoldhaploid
Genome composition5 252 367 bp · 50,0% GCEscherichia coli
Signal transduction countsGenes 66 · HK 32 · RR 34CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia

Related genes

Preview from the same derived genome key