Gene detail

FN517_RS07400

Histidine kinase, Classic

Escherichia coli · GCF_902164025

ClassHKTypeClassicLength449 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_902164025#FN517_RS07400Stable P2CS identifier used across views.
GenomeGCF_902164025Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Selected clusterHKOC_1973332Run 6 · 546 sequences · id 100% · cov 80%
External referencesWP_000673373.1 · A0A0D8WDC3 · MIST4 FN517_RS07400RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length449 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage228 / 449 aa (50.8%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa449 aa
HAMP: 164-232 aa (69 aa)1HisKA: 238-301 aa (64 aa)2HATPase_c: 348-442 aa (95 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
164-232 aa · 69 aa · 15.4% of protein
Raw tokenHAMP:164:0.00000142:232:70:69
2 HisKA#2
238-301 aa · 64 aa · 14.3% of protein
Raw tokenHisKA:238:0.00000000000462:301:64:64
3 HATPase_c#3
348-442 aa · 95 aa · 21.2% of protein
Raw tokenHATPase_c:348:1.3e-25:442:99:109
  • Raw architecture: HAMP:164:0.00000142:232:70:69#HisKA:238:0.00000000000462:301:64:64#HATPase_c:348:1.3e-25:442:99:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_902164025::NZ_CABHBW010000003.1::G00018
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span393665-395670Genomic interval covered by the local TCS group.
Context group IDGCF_902164025::NZ_CABHBW010000003.1::G00018
Context members
FN517_RS07400FN517_RS07405
Partner locus tags
FN517_RS07400FN517_RS07405
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_000673373.1Primary protein accession used for annex mappings.
UniProt accessionA0A0D8WDC3Primary UniProt accession resolved in the annex database.
UniProt IDA0A0D8WDC3_ECOLXDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagFN517_RS07400Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_CABHBW010000003.1Sequence record reported by the local genomic context database.
Genomic interval393 665-395 014 nt1 350 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span393 665-395 670 ntGCF_902164025::NZ_CABHBW010000003.1::G00018

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_902164025::NZ_CABHBW010000003.1::G00018

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CABHBW010000003.1All displayed genes belong to this local TCS context.
Neighborhood span393 665-395 670 nt2 006 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
393 665 nt395 670 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

FN517_RS07405GCF_902164025#FN517_RS07405
RROmpR

395 011-395 670 nt · Reverse (-)

RefSeq WP_001221493.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1973332Run 6 · HK · 546 sequences
Representative sequenceGCF_000164315#HMPREF9534_RS23620Use this link to inspect the representative gene detail.
PFAM architecture2CSK_N + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1973332

Simplified PFAM architecture for HKOC_1973332

PFAM domain coverage: 297 / 449 aa (66.1%)

1 aa449 aa
2CSK_N: 23-157 aa2CSK_NHisKA: 237-301 aaHisKAHATPase_c: 349-445 aaHATPase_c
2CSK_NHisKAHATPase_c
  • Simplified architecture: 2CSK_N + HisKA + HATPase_c
  • Raw architecture: 2CSK_N[23-157] | HisKA[237-301] | HATPase_c[349-445]
  • Domain count: 3
  • Matched identifier: HKOC_1973332
  • Positioned domains: 2CSK_N 23-157 ; HisKA 237-301 ; HATPase_c 349-445
Cluster members and taxonomy
Visualization

Representative gene: GCF_000164315#HMPREF9534_RS23620

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 562 · GCF_902164025
Assembly25964_2#194 · Scaffoldhaploid
Genome composition5 252 367 bp · 50,0% GCEscherichia coli
Signal transduction countsGenes 66 · HK 32 · RR 34CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia

Related genes

Preview from the same derived genome key