Gene detail

FN517_RS05605

Response regulator NtrC family

Escherichia coli · GCF_902164025

ClassRRTypeNtrCLength469 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_902164025#FN517_RS05605Stable P2CS identifier used across views.
GenomeGCF_902164025Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Selected clusterRROC_0209504Run 7 · 5673 sequences · id 100% · cov 80%
External referencesWP_001315107.1 · A0A0H2Z4V2 · MIST4 FN517_RS05605RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

Response_regAAA_5HTH_8
Protein length469 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage270 / 469 aa (57.6%)Merged over positioned domains only.
Domain description1 Response_reg,1 AAA_5,1 HTH_8Summary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa469 aa
Response_reg: 6-116 aa (111 aa)1AAA_5: 163-281 aa (119 aa)2HTH_8: 427-466 aa (40 aa)3
Domain-by-domain annotation3 items
1 Response_reg#1
6-116 aa · 111 aa · 23.7% of protein
Raw tokenResponse_reg:6:6.46e-39:116:111:111
2 AAA_5#2
163-281 aa · 119 aa · 25.4% of protein
Raw tokenAAA_5:163:0.0000000629:281:128:135
3 HTH_8#3
427-466 aa · 40 aa · 8.5% of protein
Raw tokenHTH_8:427:0.000000000000014:466:40:40
  • Raw architecture: Response_reg:6:6.46e-39:116:111:111#AAA_5:163:0.0000000629:281:128:135#HTH_8:427:0.000000000000014:466:40:40
  • Domain description: 1 Response_reg,1 AAA_5,1 HTH_8
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_902164025::NZ_CABHBW010000003.1::G00015
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span13176-15646Genomic interval covered by the local TCS group.
Context group IDGCF_902164025::NZ_CABHBW010000003.1::G00015
Context members
FN517_RS05605FN517_RS05610
Partner locus tags
FN517_RS05605FN517_RS05610
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_001315107.1Primary protein accession used for annex mappings.
UniProt accessionA0A0H2Z4V2Primary UniProt accession resolved in the annex database.
UniProt IDA0A0H2Z4V2_ECOK1Display identifier provided by UniProt.
GO / PubMed6 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagFN517_RS05605Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_CABHBW010000003.1Sequence record reported by the local genomic context database.
Genomic interval13 176-14 585 nt1 410 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span13 176-15 646 ntGCF_902164025::NZ_CABHBW010000003.1::G00015

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_902164025::NZ_CABHBW010000003.1::G00015

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CABHBW010000003.1All displayed genes belong to this local TCS context.
Neighborhood span13 176-15 646 nt2 471 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
13 176 nt15 646 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

FN517_RS05610GCF_902164025#FN517_RS05610
HKClassic

14 597-15 646 nt · Reverse (-)

RefSeq WP_000190574.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterRROC_0209504Run 7 · RR · 5673 sequences
Representative sequenceGCF_000010485#ECSF_RS19785Use this link to inspect the representative gene detail.
PFAM architectureResponse_reg + Sigma54_activat + AAA_lid_14 + HTH_84 domains in the representative PFAM annotation.

PFAM architecture for RROC_0209504

Simplified PFAM architecture for RROC_0209504

PFAM domain coverage: 400 / 469 aa (85.3%)

1 aa469 aa
Response_reg: 6-115 aaResponse_regResponse_reg: 6-115 aaResponse_regSigma54_activat: 140-306 aaSigma54_activatSigma54_activat: 140-306 aaSigma54_activatAAA_lid_14: 312-394 aaAAA_lid_14AAA_lid_14: 312-394 aaAAA_lid_14HTH_8: 427-466 aaHTH_8HTH_8: 427-466 aaHTH_8
Response_regSigma54_activatAAA_lid_14HTH_8
  • Simplified architecture: Response_reg + Sigma54_activat + AAA_lid_14 + HTH_8
  • Raw architecture: Response_reg[6-115] | Sigma54_activat[140-306] | AAA_lid_14[312-394] | HTH_8[427-466]
  • Domain count: 4
  • Matched identifier: RROC_0209504
  • Positioned domains: Response_reg 6-115 ; Response_reg 6-115 ; Sigma54_activat 140-306 ; Sigma54_activat 140-306 ; AAA_lid_14 312-394 ; AAA_lid_14 312-394 ; HTH_8 427-466 ; HTH_8 427-466
Cluster members and taxonomy
Visualization

Representative gene: GCF_000010485#ECSF_RS19785

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 562 · GCF_902164025
Assembly25964_2#194 · Scaffoldhaploid
Genome composition5 252 367 bp · 50,0% GCEscherichia coli
Signal transduction countsGenes 66 · HK 32 · RR 34CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia

Related genes

Preview from the same derived genome key