Gene detail

FN517_RS02310

Histidine kinase, Classic

Escherichia coli · GCF_902164025

ClassHKTypeClassicLength467 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_902164025#FN517_RS02310Stable P2CS identifier used across views.
GenomeGCF_902164025Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Selected clusterHKOC_1747631Run 6 · 3068 sequences · id 100% · cov 80%
External referencesWP_000675176.1 · A0AA36KYK1 · MIST4 FN517_RS02310RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length467 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage248 / 467 aa (53.1%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa467 aa
HAMP: 167-236 aa (70 aa)1HisKA: 240-304 aa (65 aa)2HATPase_c: 349-461 aa (113 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
167-236 aa · 70 aa · 15.0% of protein
Raw tokenHAMP:167:0.0000000000000284:236:70:69
2 HisKA#2
240-304 aa · 65 aa · 13.9% of protein
Raw tokenHisKA:240:0.00000000000000821:304:65:64
3 HATPase_c#3
349-461 aa · 113 aa · 24.2% of protein
Raw tokenHATPase_c:349:2.41e-29:461:113:109
  • Raw architecture: HAMP:167:0.0000000000000284:236:70:69#HisKA:240:0.00000000000000821:304:65:64#HATPase_c:349:2.41e-29:461:113:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_902164025::NZ_CABHBW010000001.1::G00011
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span522889-525011Genomic interval covered by the local TCS group.
Context group IDGCF_902164025::NZ_CABHBW010000001.1::G00011
Context members
FN517_RS02305FN517_RS02310
Partner locus tags
FN517_RS02305FN517_RS02310
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_000675176.1Primary protein accession used for annex mappings.
UniProt accessionA0AA36KYK1Primary UniProt accession resolved in the annex database.
UniProt IDA0AA36KYK1_ECOLXDisplay identifier provided by UniProt.
GO / PubMed5 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagFN517_RS02310Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_CABHBW010000001.1Sequence record reported by the local genomic context database.
Genomic interval523 608-525 011 nt1 404 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span522 889-525 011 ntGCF_902164025::NZ_CABHBW010000001.1::G00011

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_902164025::NZ_CABHBW010000001.1::G00011

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CABHBW010000001.1All displayed genes belong to this local TCS context.
Neighborhood span522 889-525 011 nt2 123 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
522 889 nt525 011 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

FN517_RS02305GCF_902164025#FN517_RS02305
RROmpR

522 889-523 611 nt · Reverse (-)

RefSeq WP_000137877.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1747631Run 6 · HK · 3068 sequences
Representative sequenceGCF_000010485#ECSF_RS10510Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1747631

Simplified PFAM architecture for HKOC_1747631

PFAM domain coverage: 228 / 467 aa (48.8%)

1 aa467 aa
HAMP: 185-235 aaHAMPHisKA: 240-304 aaHisKAHATPase_c: 349-460 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[185-235] | HisKA[240-304] | HATPase_c[349-460]
  • Domain count: 3
  • Matched identifier: HKOC_1747631
  • Positioned domains: HAMP 185-235 ; HisKA 240-304 ; HATPase_c 349-460
Cluster members and taxonomy
Visualization

Representative gene: GCF_000010485#ECSF_RS10510

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 562 · GCF_902164025
Assembly25964_2#194 · Scaffoldhaploid
Genome composition5 252 367 bp · 50,0% GCEscherichia coli
Signal transduction countsGenes 66 · HK 32 · RR 34CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia

Related genes

Preview from the same derived genome key