Gene detail

NE546_RS19085

Histidine kinase, Classic

Neglectibacter timonensis · GCF_024460865

ClassHKTypeClassicLength592 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_024460865#NE546_RS19085Stable P2CS identifier used across views.
GenomeGCF_024460865Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae; Neglectibacter
Selected clusterHKOC_1102520Run 6 · 6 sequences · id 100% · cov 80% · representative
External referencesWP_066863797.1 · A0ABT1RUG4 · MIST4 NE546_RS19085RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHis_kinaseHATPase_c
Protein length592 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage251 / 592 aa (42.4%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa592 aa
HAMP: 298-366 aa (69 aa)1His_kinase: 381-460 aa (80 aa)2HATPase_c: 480-581 aa (102 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
298-366 aa · 69 aa · 11.7% of protein
Raw tokenHAMP:298:0.00000793:366:69:69
2 His_kinase#2
381-460 aa · 80 aa · 13.5% of protein
Raw tokenHis_kinase:381:8.64e-31:460:80:80
3 HATPase_c#3
480-581 aa · 102 aa · 17.2% of protein
Raw tokenHATPase_c:480:0.0000000000016:581:106:109
  • Raw architecture: HAMP:298:0.00000793:366:69:69#His_kinase:381:8.64e-31:460:80:80#HATPase_c:480:0.0000000000016:581:106:109
  • Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_024460865::NZ_JANFZG010000002.1::G00016
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span13603-16945Genomic interval covered by the local TCS group.
Identifiers
Old locus tagNE546_00985RefSeq proteinWP_066863797.1
Context group IDGCF_024460865::NZ_JANFZG010000002.1::G00016
Context members
NE546_RS19085NE546_RS00990
Partner locus tags
NE546_RS19085NE546_RS00990
Partner old locus tags
NE546_00985NE546_00990
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_066863797.1Primary protein accession used for annex mappings.
UniProt accessionA0ABT1RUG4Primary UniProt accession resolved in the annex database.
UniProt IDA0ABT1RUG4_9FIRMDisplay identifier provided by UniProt.
GO / PubMed1 / 0Unique GO terms and literature references available below.
GO terms

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagNE546_RS19085Primary locus identifier stored in the genes table.
Old locus tagNE546_00985Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JANFZG010000002.1Sequence record reported by the local genomic context database.
Genomic interval13 603-15 381 nt1 779 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span13 603-16 945 ntGCF_024460865::NZ_JANFZG010000002.1::G00016

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_024460865::NZ_JANFZG010000002.1::G00016

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JANFZG010000002.1All displayed genes belong to this local TCS context.
Neighborhood span13 603-16 945 nt3 343 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
13 603 nt16 945 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

NE546_RS19085GCF_024460865#NE546_RS19085
HKClassicCurrent focus

13 603-15 381 nt · Forward (+)

Old locus NE546_00985RefSeq WP_066863797.1
NE546_RS00990GCF_024460865#NE546_RS00990
RRunclassified

15 383-16 945 nt · Forward (+)

Old locus NE546_00990RefSeq WP_066863791.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1102520Run 6 · HK · 6 sequences
Representative sequenceGCF_024460865#NE546_RS19085The current gene is the representative for this cluster.
PFAM architectureHis_kinase + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1102520

Simplified PFAM architecture for HKOC_1102520

PFAM domain coverage: 181 / 592 aa (30.6%)

1 aa592 aa
His_kinase: 381-460 aaHis_kinaseHATPase_c: 481-581 aaHATPase_c
His_kinaseHATPase_c
  • Simplified architecture: His_kinase + HATPase_c
  • Raw architecture: His_kinase[381-460] | HATPase_c[481-581]
  • Domain count: 2
  • Matched identifier: HKOC_1102520
  • Positioned domains: His_kinase 381-460 ; HATPase_c 481-581
Cluster members and taxonomy
Visualization

Representative gene: GCF_024460865#NE546_RS19085

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 776 382 · GCF_024460865
AssemblyASM2446086v1 · Contighaploid
Genome composition4 030 546 bp · 52,5% GCNeglectibacter timonensis
Signal transduction countsGenes 113 · HK 57 · RR 53CheA 0 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyOscillospiraceaeGenusNeglectibacter
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Oscillospiraceae7Neglectibacter

Related genes

Preview from the same derived genome key