Gene detail

NE546_RS17475

Histidine kinase, Hybrid

Neglectibacter timonensis · GCF_024460865

ClassHKTypeHybridLength1197 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_024460865#NE546_RS17475Stable P2CS identifier used across views.
GenomeGCF_024460865Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae; Neglectibacter
Selected clusterHKOC_0163102Run 6 · 6 sequences · id 100% · cov 80% · representative
External referencesWP_066862367.1 · A0ABT1S3Z4 · MIST4 NE546_RS17475RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

PAS_3HisKAHATPase_cResponse_reg
Protein length1197 aaLength used to scale native and Biotite-like views.
Annotated domains66 with usable coordinates.
Domain coverage583 / 1197 aa (48.7%)Merged over positioned domains only.
Domain description2 PAS_3,1 HisKA,1 HATPase_c,2 Response_regSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa1197 aa
PAS_3: 174-255 aa (82 aa)1PAS_3: 296-380 aa (85 aa)2HisKA: 679-745 aa (67 aa)3HATPase_c: 792-909 aa (118 aa)4Response_reg: 932-1045 aa (114 aa)5Response_reg: 1072-1188 aa (117 aa)6
Domain-by-domain annotation6 items
1 PAS_3#1
174-255 aa · 82 aa · 6.9% of protein
Raw tokenPAS_3:174:2.99e-17:255:82:89
2 PAS_3#2
296-380 aa · 85 aa · 7.1% of protein
Raw tokenPAS_3:296:0.000000000002:380:85:89
3 HisKA#3
679-745 aa · 67 aa · 5.6% of protein
Raw tokenHisKA:679:0.0000000000000127:745:67:64
4 HATPase_c#4
792-909 aa · 118 aa · 9.9% of protein
Raw tokenHATPase_c:792:2.62e-30:909:118:109
5 Response_reg#5
932-1045 aa · 114 aa · 9.5% of protein
Raw tokenResponse_reg:932:1.55e-20:1045:114:111
6 Response_reg#6
1072-1188 aa · 117 aa · 9.8% of protein
Raw tokenResponse_reg:1072:2.13e-27:1188:117:111
  • Raw architecture: PAS_3:174:2.99e-17:255:82:89#PAS_3:296:0.000000000002:380:85:89#HisKA:679:0.0000000000000127:745:67:64#HATPase_c:792:2.62e-30:909:118:109#Response_reg:932:1.55e-20:1045:114:111#Response_reg:1072:2.13e-27:1188:117:111
  • Domain description: 2 PAS_3,1 HisKA,1 HATPase_c,2 Response_reg
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_024460865::NZ_JANFZG010000064.1::G00052
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span352-6515Genomic interval covered by the local TCS group.
Identifiers
Old locus tagNE546_17480RefSeq proteinWP_066862367.1
Context group IDGCF_024460865::NZ_JANFZG010000064.1::G00052
Context members
NE546_RS17470NE546_RS17475
Partner locus tags
NE546_RS17470NE546_RS17475
Partner old locus tags
NE546_17475NE546_17480
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_066862367.1Primary protein accession used for annex mappings.
UniProt accessionA0ABT1S3Z4Primary UniProt accession resolved in the annex database.
UniProt IDA0ABT1S3Z4_9FIRMDisplay identifier provided by UniProt.
GO / PubMed0 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagNE546_RS17475Primary locus identifier stored in the genes table.
Old locus tagNE546_17480Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JANFZG010000064.1Sequence record reported by the local genomic context database.
Genomic interval2 922-6 515 nt3 594 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span352-6 515 ntGCF_024460865::NZ_JANFZG010000064.1::G00052

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_024460865::NZ_JANFZG010000064.1::G00052

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JANFZG010000064.1All displayed genes belong to this local TCS context.
Neighborhood span352-6 515 nt6 164 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
352 nt6 515 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

NE546_RS17470GCF_024460865#NE546_RS17470
RRPleD_VieA

352-2 898 nt · Forward (+)

Old locus NE546_17475RefSeq WP_066862369.1
NE546_RS17475GCF_024460865#NE546_RS17475
HKHybridCurrent focus

2 922-6 515 nt · Forward (+)

Old locus NE546_17480RefSeq WP_066862367.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0163102Run 6 · HK · 6 sequences
Representative sequenceGCF_024460865#NE546_RS17475The current gene is the representative for this cluster.
PFAM architecturePAS_3 + PAS_3 + HisKA + HATPase_c + Response_reg + Response_reg6 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0163102

Simplified PFAM architecture for HKOC_0163102

PFAM domain coverage: 581 / 1197 aa (48.5%)

1 aa1197 aa
PAS_3: 174-256 aaPAS_3PAS_3: 297-380 aaPAS_3HisKA: 679-745 aaHisKAHATPase_c: 792-907 aaHATPase_cResponse_reg: 932-1045 aaResponse_regResponse_reg: 1072-1188 aaResponse_reg
PAS_3PAS_3HisKAHATPase_cResponse_regResponse_reg
  • Simplified architecture: PAS_3 + PAS_3 + HisKA + HATPase_c + Response_reg + Response_reg
  • Raw architecture: PAS_3[174-256] | PAS_3[297-380] | HisKA[679-745] | HATPase_c[792-907] | Response_reg[932-1045] | Response_reg[1072-1188]
  • Domain count: 6
  • Matched identifier: HKOC_0163102
  • Positioned domains: PAS_3 174-256 ; PAS_3 297-380 ; HisKA 679-745 ; HATPase_c 792-907 ; Response_reg 932-1045 ; Response_reg 1072-1188
Cluster members and taxonomy
Visualization

Representative gene: GCF_024460865#NE546_RS17475

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 776 382 · GCF_024460865
AssemblyASM2446086v1 · Contighaploid
Genome composition4 030 546 bp · 52,5% GCNeglectibacter timonensis
Signal transduction countsGenes 113 · HK 57 · RR 53CheA 0 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyOscillospiraceaeGenusNeglectibacter
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Oscillospiraceae7Neglectibacter

Related genes

Preview from the same derived genome key