Gene detail

NE546_RS16710

Histidine kinase, Hybrid

Neglectibacter timonensis · GCF_024460865

ClassHKTypeHybridLength1107 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_024460865#NE546_RS16710Stable P2CS identifier used across views.
GenomeGCF_024460865Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae; Neglectibacter
Selected clusterHKOC_0228447Run 6 · 8 sequences · id 100% · cov 80% · representative
External referencesWP_066866400.1 · A0ABT1S3T0 · MIST4 NE546_RS16710RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

PAS_3HisKAHATPase_cResponse_reg
Protein length1107 aaLength used to scale native and Biotite-like views.
Annotated domains66 with usable coordinates.
Domain coverage520 / 1107 aa (47.0%)Merged over positioned domains only.
Domain description3 PAS_3,1 HisKA,1 HATPase_c,1 Response_regSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa1107 aa
PAS_3: 201-280 aa (80 aa)1PAS_3: 333-408 aa (76 aa)2PAS_3: 490-549 aa (60 aa)3HisKA: 726-792 aa (67 aa)4HATPase_c: 838-955 aa (118 aa)5Response_reg: 982-1100 aa (119 aa)6
Domain-by-domain annotation6 items
1 PAS_3#1
201-280 aa · 80 aa · 7.2% of protein
Raw tokenPAS_3:201:0.00000000000000867:280:80:89
2 PAS_3#2
333-408 aa · 76 aa · 6.9% of protein
Raw tokenPAS_3:333:0.000000116:408:78:89
3 PAS_3#3
490-549 aa · 60 aa · 5.4% of protein
Raw tokenPAS_3:490:0.0000000324:549:65:89
4 HisKA#4
726-792 aa · 67 aa · 6.1% of protein
Raw tokenHisKA:726:3.96e-18:792:67:64
5 HATPase_c#5
838-955 aa · 118 aa · 10.7% of protein
Raw tokenHATPase_c:838:3.5e-32:955:118:109
6 Response_reg#6
982-1100 aa · 119 aa · 10.7% of protein
Raw tokenResponse_reg:982:2.77e-29:1100:119:111
  • Raw architecture: PAS_3:201:0.00000000000000867:280:80:89#PAS_3:333:0.000000116:408:78:89#PAS_3:490:0.0000000324:549:65:89#HisKA:726:3.96e-18:792:67:64#HATPase_c:838:3.5e-32:955:118:109#Response_reg:982:2.77e-29:1100:119:111
  • Domain description: 3 PAS_3,1 HisKA,1 HATPase_c,1 Response_reg
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_024460865::NZ_JANFZG010000053.1::G00046
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span18617-21940Genomic interval covered by the local TCS group.
Identifiers
Old locus tagNE546_16710RefSeq proteinWP_066866400.1
Context group IDGCF_024460865::NZ_JANFZG010000053.1::G00046
Context members
NE546_RS16710
Partner locus tags
NE546_RS16710
Partner old locus tags
NE546_16710
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_066866400.1Primary protein accession used for annex mappings.
UniProt accessionA0ABT1S3T0Primary UniProt accession resolved in the annex database.
UniProt IDA0ABT1S3T0_9FIRMDisplay identifier provided by UniProt.
GO / PubMed0 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagNE546_RS16710Primary locus identifier stored in the genes table.
Old locus tagNE546_16710Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JANFZG010000053.1Sequence record reported by the local genomic context database.
Genomic interval18 617-21 940 nt3 324 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span18 617-21 940 ntGCF_024460865::NZ_JANFZG010000053.1::G00046

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_024460865::NZ_JANFZG010000053.1::G00046

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JANFZG010000053.1All displayed genes belong to this local TCS context.
Neighborhood span18 617-21 940 nt3 324 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
18 617 nt21 940 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

NE546_RS16710GCF_024460865#NE546_RS16710
HKHybridCurrent focus

18 617-21 940 nt · Reverse (-)

Old locus NE546_16710RefSeq WP_066866400.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0228447Run 6 · HK · 8 sequences
Representative sequenceGCF_024460865#NE546_RS16710The current gene is the representative for this cluster.
PFAM architecturePAS_3 + PAS_3 + HisKA + HATPase_c + Response_reg5 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0228447

Simplified PFAM architecture for HKOC_0228447

PFAM domain coverage: 466 / 1107 aa (42.1%)

1 aa1107 aa
PAS_3: 201-280 aaPAS_3PAS_3: 334-417 aaPAS_3HisKA: 726-792 aaHisKAHATPase_c: 838-953 aaHATPase_cResponse_reg: 982-1100 aaResponse_reg
PAS_3PAS_3HisKAHATPase_cResponse_reg
  • Simplified architecture: PAS_3 + PAS_3 + HisKA + HATPase_c + Response_reg
  • Raw architecture: PAS_3[201-280] | PAS_3[334-417] | HisKA[726-792] | HATPase_c[838-953] | Response_reg[982-1100]
  • Domain count: 5
  • Matched identifier: HKOC_0228447
  • Positioned domains: PAS_3 201-280 ; PAS_3 334-417 ; HisKA 726-792 ; HATPase_c 838-953 ; Response_reg 982-1100
Cluster members and taxonomy
Visualization

Representative gene: GCF_024460865#NE546_RS16710

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 776 382 · GCF_024460865
AssemblyASM2446086v1 · Contighaploid
Genome composition4 030 546 bp · 52,5% GCNeglectibacter timonensis
Signal transduction countsGenes 113 · HK 57 · RR 53CheA 0 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyOscillospiraceaeGenusNeglectibacter
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Oscillospiraceae7Neglectibacter

Related genes

Preview from the same derived genome key