Gene detail

NE546_RS15585

Histidine kinase, Classic

Neglectibacter timonensis · GCF_024460865

ClassHKTypeClassicLength590 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_024460865#NE546_RS15585Stable P2CS identifier used across views.
GenomeGCF_024460865Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae; Neglectibacter
Selected clusterHKOC_1112838Run 6 · 2 sequences · id 100% · cov 80% · representative
External referencesWP_256192297.1 · A0ABT1S3C2 · MIST4 NE546_RS15585RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

dCache_1HAMPHis_kinaseHATPase_c
Protein length590 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage357 / 590 aa (60.5%)Merged over positioned domains only.
Domain description1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa590 aa
dCache_1: 176-274 aa (99 aa)1HAMP: 296-363 aa (68 aa)2His_kinase: 378-457 aa (80 aa)3HATPase_c: 473-582 aa (110 aa)4
Domain-by-domain annotation4 items
1 dCache_1#1
176-274 aa · 99 aa · 16.8% of protein
Raw tokendCache_1:176:0.0000255:274:109:195
2 HAMP#2
296-363 aa · 68 aa · 11.5% of protein
Raw tokenHAMP:296:0.000000336:363:68:69
3 His_kinase#3
378-457 aa · 80 aa · 13.6% of protein
Raw tokenHis_kinase:378:6.37e-28:457:80:80
4 HATPase_c#4
473-582 aa · 110 aa · 18.6% of protein
Raw tokenHATPase_c:473:0.000000000000419:582:117:109
  • Raw architecture: dCache_1:176:0.0000255:274:109:195#HAMP:296:0.000000336:363:68:69#His_kinase:378:6.37e-28:457:80:80#HATPase_c:473:0.000000000000419:582:117:109
  • Domain description: 1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_024460865::NZ_JANFZG010000045.1::G00041
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span87-3423Genomic interval covered by the local TCS group.
Identifiers
Old locus tagNE546_15585RefSeq proteinWP_256192297.1
Context group IDGCF_024460865::NZ_JANFZG010000045.1::G00041
Context members
NE546_RS15585NE546_RS15590
Partner locus tags
NE546_RS15585NE546_RS15590
Partner old locus tags
NE546_15585NE546_15590
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_256192297.1Primary protein accession used for annex mappings.
UniProt accessionA0ABT1S3C2Primary UniProt accession resolved in the annex database.
UniProt IDA0ABT1S3C2_9FIRMDisplay identifier provided by UniProt.
GO / PubMed1 / 0Unique GO terms and literature references available below.
GO terms

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagNE546_RS15585Primary locus identifier stored in the genes table.
Old locus tagNE546_15585Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JANFZG010000045.1Sequence record reported by the local genomic context database.
Genomic interval87-1 859 nt1 773 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span87-3 423 ntGCF_024460865::NZ_JANFZG010000045.1::G00041

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_024460865::NZ_JANFZG010000045.1::G00041

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JANFZG010000045.1All displayed genes belong to this local TCS context.
Neighborhood span87-3 423 nt3 337 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
87 nt3 423 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

NE546_RS15590GCF_024460865#NE546_RS15590
RRunclassified

1 852-3 423 nt · Forward (+)

Old locus NE546_15590RefSeq WP_256192296.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1112838Run 6 · HK · 2 sequences
Representative sequenceGCF_024460865#NE546_RS15585The current gene is the representative for this cluster.
PFAM architectureHis_kinase + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1112838

Simplified PFAM architecture for HKOC_1112838

PFAM domain coverage: 190 / 590 aa (32.2%)

1 aa590 aa
His_kinase: 378-456 aaHis_kinaseHATPase_c: 471-581 aaHATPase_c
His_kinaseHATPase_c
  • Simplified architecture: His_kinase + HATPase_c
  • Raw architecture: His_kinase[378-456] | HATPase_c[471-581]
  • Domain count: 2
  • Matched identifier: HKOC_1112838
  • Positioned domains: His_kinase 378-456 ; HATPase_c 471-581
Cluster members and taxonomy
Visualization

Representative gene: GCF_024460865#NE546_RS15585

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 776 382 · GCF_024460865
AssemblyASM2446086v1 · Contighaploid
Genome composition4 030 546 bp · 52,5% GCNeglectibacter timonensis
Signal transduction countsGenes 113 · HK 57 · RR 53CheA 0 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyOscillospiraceaeGenusNeglectibacter
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Oscillospiraceae7Neglectibacter

Related genes

Preview from the same derived genome key