Gene detail

NE546_RS14995

Histidine kinase, Hybrid

Neglectibacter timonensis · GCF_024460865

ClassHKTypeHybridLength1062 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_024460865#NE546_RS14995Stable P2CS identifier used across views.
GenomeGCF_024460865Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae; Neglectibacter
Selected clusterHKOC_0251661Run 6 · 3 sequences · id 100% · cov 80% · representative
External referencesWP_256192253.1 · A0ABT1S2I9 · MIST4 NE546_RS14995RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

PAS_9HisKAHATPase_cResponse_reg
Protein length1062 aaLength used to scale native and Biotite-like views.
Annotated domains66 with usable coordinates.
Domain coverage621 / 1062 aa (58.5%)Merged over positioned domains only.
Domain description2 PAS_9,1 HisKA,1 HATPase_c,2 Response_regSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa1062 aa
PAS_9: 37-141 aa (105 aa)1PAS_9: 298-402 aa (105 aa)2HisKA: 553-619 aa (67 aa)3HATPase_c: 667-780 aa (114 aa)4Response_reg: 799-910 aa (112 aa)5Response_reg: 942-1059 aa (118 aa)6
Domain-by-domain annotation6 items
1 PAS_9#1
37-141 aa · 105 aa · 9.9% of protein
Raw tokenPAS_9:37:0.00000402:141:105:102
2 PAS_9#2
298-402 aa · 105 aa · 9.9% of protein
Raw tokenPAS_9:298:0.000000227:402:105:102
3 HisKA#3
553-619 aa · 67 aa · 6.3% of protein
Raw tokenHisKA:553:0.0000000000000126:619:67:64
4 HATPase_c#4
667-780 aa · 114 aa · 10.7% of protein
Raw tokenHATPase_c:667:8.42e-32:780:114:109
5 Response_reg#5
799-910 aa · 112 aa · 10.5% of protein
Raw tokenResponse_reg:799:5.96e-26:910:112:111
6 Response_reg#6
942-1059 aa · 118 aa · 11.1% of protein
Raw tokenResponse_reg:942:1.96e-30:1059:118:111
  • Raw architecture: PAS_9:37:0.00000402:141:105:102#PAS_9:298:0.000000227:402:105:102#HisKA:553:0.0000000000000126:619:67:64#HATPase_c:667:8.42e-32:780:114:109#Response_reg:799:5.96e-26:910:112:111#Response_reg:942:1.96e-30:1059:118:111
  • Domain description: 2 PAS_9,1 HisKA,1 HATPase_c,2 Response_reg
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_024460865::NZ_JANFZG010000041.1::G00038
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span14880-18068Genomic interval covered by the local TCS group.
Identifiers
Old locus tagNE546_14995RefSeq proteinWP_256192253.1
Context group IDGCF_024460865::NZ_JANFZG010000041.1::G00038
Context members
NE546_RS14995
Partner locus tags
NE546_RS14995
Partner old locus tags
NE546_14995
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_256192253.1Primary protein accession used for annex mappings.
UniProt accessionA0ABT1S2I9Primary UniProt accession resolved in the annex database.
UniProt IDA0ABT1S2I9_9FIRMDisplay identifier provided by UniProt.
GO / PubMed0 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagNE546_RS14995Primary locus identifier stored in the genes table.
Old locus tagNE546_14995Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JANFZG010000041.1Sequence record reported by the local genomic context database.
Genomic interval14 880-18 068 nt3 189 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span14 880-18 068 ntGCF_024460865::NZ_JANFZG010000041.1::G00038

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_024460865::NZ_JANFZG010000041.1::G00038

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JANFZG010000041.1All displayed genes belong to this local TCS context.
Neighborhood span14 880-18 068 nt3 189 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
14 880 nt18 068 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

NE546_RS14995GCF_024460865#NE546_RS14995
HKHybridCurrent focus

14 880-18 068 nt · Forward (+)

Old locus NE546_14995RefSeq WP_256192253.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0251661Run 6 · HK · 3 sequences
Representative sequenceGCF_024460865#NE546_RS14995The current gene is the representative for this cluster.
PFAM architecturePAS_9 + HisKA + HATPase_c + Response_reg + Response_reg5 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0251661

Simplified PFAM architecture for HKOC_0251661

PFAM domain coverage: 516 / 1062 aa (48.6%)

1 aa1062 aa
PAS_9: 298-402 aaPAS_9HisKA: 553-619 aaHisKAHATPase_c: 667-780 aaHATPase_cResponse_reg: 799-912 aaResponse_regResponse_reg: 942-1057 aaResponse_reg
PAS_9HisKAHATPase_cResponse_regResponse_reg
  • Simplified architecture: PAS_9 + HisKA + HATPase_c + Response_reg + Response_reg
  • Raw architecture: PAS_9[298-402] | HisKA[553-619] | HATPase_c[667-780] | Response_reg[799-912] | Response_reg[942-1057]
  • Domain count: 5
  • Matched identifier: HKOC_0251661
  • Positioned domains: PAS_9 298-402 ; HisKA 553-619 ; HATPase_c 667-780 ; Response_reg 799-912 ; Response_reg 942-1057
Cluster members and taxonomy
Visualization

Representative gene: GCF_024460865#NE546_RS14995

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 776 382 · GCF_024460865
AssemblyASM2446086v1 · Contighaploid
Genome composition4 030 546 bp · 52,5% GCNeglectibacter timonensis
Signal transduction countsGenes 113 · HK 57 · RR 53CheA 0 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyOscillospiraceaeGenusNeglectibacter
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Oscillospiraceae7Neglectibacter

Related genes

Preview from the same derived genome key