Gene detail

NE546_RS10915

Histidine kinase, Hybrid

Neglectibacter timonensis · GCF_024460865

ClassHKTypeHybridLength811 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_024460865#NE546_RS10915Stable P2CS identifier used across views.
GenomeGCF_024460865Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae; Neglectibacter
Selected clusterHKOC_0539527Run 6 · 6 sequences · id 100% · cov 80% · representative
External referencesWP_066864036.1 · A0ABT1S0U6 · MIST4 NE546_RS10915RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

PAS_3HisKAHATPase_cResponse_reg
Protein length811 aaLength used to scale native and Biotite-like views.
Annotated domains55 with usable coordinates.
Domain coverage489 / 811 aa (60.3%)Merged over positioned domains only.
Domain description1 PAS_3,1 HisKA,1 HATPase_c,2 Response_regSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa811 aa
PAS_3: 47-118 aa (72 aa)1HisKA: 293-359 aa (67 aa)2HATPase_c: 406-522 aa (117 aa)3Response_reg: 543-658 aa (116 aa)4Response_reg: 687-803 aa (117 aa)5
Domain-by-domain annotation5 items
1 PAS_3#1
47-118 aa · 72 aa · 8.9% of protein
Raw tokenPAS_3:47:0.00000877:118:72:89
2 HisKA#2
293-359 aa · 67 aa · 8.3% of protein
Raw tokenHisKA:293:2.02e-16:359:67:64
3 HATPase_c#3
406-522 aa · 117 aa · 14.4% of protein
Raw tokenHATPase_c:406:4.17e-31:522:117:109
4 Response_reg#4
543-658 aa · 116 aa · 14.3% of protein
Raw tokenResponse_reg:543:6.61e-25:658:116:111
5 Response_reg#5
687-803 aa · 117 aa · 14.4% of protein
Raw tokenResponse_reg:687:5.55e-34:803:117:111
  • Raw architecture: PAS_3:47:0.00000877:118:72:89#HisKA:293:2.02e-16:359:67:64#HATPase_c:406:4.17e-31:522:117:109#Response_reg:543:6.61e-25:658:116:111#Response_reg:687:5.55e-34:803:117:111
  • Domain description: 1 PAS_3,1 HisKA,1 HATPase_c,2 Response_reg
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_024460865::NZ_JANFZG010000022.1::G00024
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span51159-53594Genomic interval covered by the local TCS group.
Identifiers
Old locus tagNE546_10915RefSeq proteinWP_066864036.1
Context group IDGCF_024460865::NZ_JANFZG010000022.1::G00024
Context members
NE546_RS10915
Partner locus tags
NE546_RS10915
Partner old locus tags
NE546_10915
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_066864036.1Primary protein accession used for annex mappings.
UniProt accessionA0ABT1S0U6Primary UniProt accession resolved in the annex database.
UniProt IDA0ABT1S0U6_9FIRMDisplay identifier provided by UniProt.
GO / PubMed0 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagNE546_RS10915Primary locus identifier stored in the genes table.
Old locus tagNE546_10915Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JANFZG010000022.1Sequence record reported by the local genomic context database.
Genomic interval51 159-53 594 nt2 436 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span51 159-53 594 ntGCF_024460865::NZ_JANFZG010000022.1::G00024

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_024460865::NZ_JANFZG010000022.1::G00024

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JANFZG010000022.1All displayed genes belong to this local TCS context.
Neighborhood span51 159-53 594 nt2 436 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
51 159 nt53 594 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

NE546_RS10915GCF_024460865#NE546_RS10915
HKHybridCurrent focus

51 159-53 594 nt · Forward (+)

Old locus NE546_10915RefSeq WP_066864036.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0539527Run 6 · HK · 6 sequences
Representative sequenceGCF_024460865#NE546_RS10915The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c + Response_reg + Response_reg4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0539527

Simplified PFAM architecture for HKOC_0539527

PFAM domain coverage: 415 / 811 aa (51.2%)

1 aa811 aa
HisKA: 293-359 aaHisKAHATPase_c: 406-521 aaHATPase_cResponse_reg: 543-658 aaResponse_regResponse_reg: 687-802 aaResponse_reg
HisKAHATPase_cResponse_regResponse_reg
  • Simplified architecture: HisKA + HATPase_c + Response_reg + Response_reg
  • Raw architecture: HisKA[293-359] | HATPase_c[406-521] | Response_reg[543-658] | Response_reg[687-802]
  • Domain count: 4
  • Matched identifier: HKOC_0539527
  • Positioned domains: HisKA 293-359 ; HATPase_c 406-521 ; Response_reg 543-658 ; Response_reg 687-802
Cluster members and taxonomy
Visualization

Representative gene: GCF_024460865#NE546_RS10915

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 776 382 · GCF_024460865
AssemblyASM2446086v1 · Contighaploid
Genome composition4 030 546 bp · 52,5% GCNeglectibacter timonensis
Signal transduction countsGenes 113 · HK 57 · RR 53CheA 0 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyOscillospiraceaeGenusNeglectibacter
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Oscillospiraceae7Neglectibacter

Related genes

Preview from the same derived genome key