Gene detail

NE546_RS08245

Histidine kinase, Hybrid

Neglectibacter timonensis · GCF_024460865

ClassHKTypeHybridLength867 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_024460865#NE546_RS08245Stable P2CS identifier used across views.
GenomeGCF_024460865Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae; Neglectibacter
Selected clusterHKOC_0463104Run 6 · 6 sequences · id 100% · cov 80% · representative
External referencesWP_066867056.1 · A0ABT1RYQ4 · MIST4 NE546_RS08245RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

PAS_3HisKAHATPase_cResponse_reg
Protein length867 aaLength used to scale native and Biotite-like views.
Annotated domains55 with usable coordinates.
Domain coverage490 / 867 aa (56.5%)Merged over positioned domains only.
Domain description1 PAS_3,1 HisKA,1 HATPase_c,2 Response_regSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa867 aa
PAS_3: 243-324 aa (82 aa)1HisKA: 353-419 aa (67 aa)2HATPase_c: 466-583 aa (118 aa)3Response_reg: 603-709 aa (107 aa)4Response_reg: 746-861 aa (116 aa)5
Domain-by-domain annotation5 items
1 PAS_3#1
243-324 aa · 82 aa · 9.5% of protein
Raw tokenPAS_3:243:0.000000566:324:87:89
2 HisKA#2
353-419 aa · 67 aa · 7.7% of protein
Raw tokenHisKA:353:0.00000000000000549:419:67:64
3 HATPase_c#3
466-583 aa · 118 aa · 13.6% of protein
Raw tokenHATPase_c:466:2.55e-31:583:118:109
4 Response_reg#4
603-709 aa · 107 aa · 12.3% of protein
Raw tokenResponse_reg:603:1.49e-19:709:107:111
5 Response_reg#5
746-861 aa · 116 aa · 13.4% of protein
Raw tokenResponse_reg:746:1.62e-31:861:116:111
  • Raw architecture: PAS_3:243:0.000000566:324:87:89#HisKA:353:0.00000000000000549:419:67:64#HATPase_c:466:2.55e-31:583:118:109#Response_reg:603:1.49e-19:709:107:111#Response_reg:746:1.62e-31:861:116:111
  • Domain description: 1 PAS_3,1 HisKA,1 HATPase_c,2 Response_reg
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_024460865::NZ_JANFZG010000015.1::G00011
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span13586-16189Genomic interval covered by the local TCS group.
Identifiers
Old locus tagNE546_08245RefSeq proteinWP_066867056.1
Context group IDGCF_024460865::NZ_JANFZG010000015.1::G00011
Context members
NE546_RS08245
Partner locus tags
NE546_RS08245
Partner old locus tags
NE546_08245
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_066867056.1Primary protein accession used for annex mappings.
UniProt accessionA0ABT1RYQ4Primary UniProt accession resolved in the annex database.
UniProt IDA0ABT1RYQ4_9FIRMDisplay identifier provided by UniProt.
GO / PubMed0 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagNE546_RS08245Primary locus identifier stored in the genes table.
Old locus tagNE546_08245Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JANFZG010000015.1Sequence record reported by the local genomic context database.
Genomic interval13 586-16 189 nt2 604 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span13 586-16 189 ntGCF_024460865::NZ_JANFZG010000015.1::G00011

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_024460865::NZ_JANFZG010000015.1::G00011

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JANFZG010000015.1All displayed genes belong to this local TCS context.
Neighborhood span13 586-16 189 nt2 604 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
13 586 nt16 189 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

NE546_RS08245GCF_024460865#NE546_RS08245
HKHybridCurrent focus

13 586-16 189 nt · Forward (+)

Old locus NE546_08245RefSeq WP_066867056.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0463104Run 6 · HK · 6 sequences
Representative sequenceGCF_024460865#NE546_RS08245The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c + Response_reg + Response_reg4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0463104

Simplified PFAM architecture for HKOC_0463104

PFAM domain coverage: 414 / 867 aa (47.8%)

1 aa867 aa
HisKA: 353-419 aaHisKAHATPase_c: 466-582 aaHATPase_cResponse_reg: 603-716 aaResponse_regResponse_reg: 746-861 aaResponse_reg
HisKAHATPase_cResponse_regResponse_reg
  • Simplified architecture: HisKA + HATPase_c + Response_reg + Response_reg
  • Raw architecture: HisKA[353-419] | HATPase_c[466-582] | Response_reg[603-716] | Response_reg[746-861]
  • Domain count: 4
  • Matched identifier: HKOC_0463104
  • Positioned domains: HisKA 353-419 ; HATPase_c 466-582 ; Response_reg 603-716 ; Response_reg 746-861
Cluster members and taxonomy
Visualization

Representative gene: GCF_024460865#NE546_RS08245

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 776 382 · GCF_024460865
AssemblyASM2446086v1 · Contighaploid
Genome composition4 030 546 bp · 52,5% GCNeglectibacter timonensis
Signal transduction countsGenes 113 · HK 57 · RR 53CheA 0 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyOscillospiraceaeGenusNeglectibacter
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Oscillospiraceae7Neglectibacter

Related genes

Preview from the same derived genome key