Gene detail

NE546_RS07865

Histidine kinase, Hybrid

Neglectibacter timonensis · GCF_024460865

ClassHKTypeHybridLength876 aaTM0ValidatedNoCompleteYesContexttriad
Gene IDGCF_024460865#NE546_RS07865Stable P2CS identifier used across views.
GenomeGCF_024460865Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae; Neglectibacter
Selected clusterHKOC_0452606Run 6 · 5 sequences · id 100% · cov 80% · representative
External referencesWP_066862721.1 · A0ABT1RYJ6 · MIST4 NE546_RS07865RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_cResponse_reg
Protein length876 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage405 / 876 aa (46.2%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_c,2 Response_regSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa876 aa
HisKA: 359-424 aa (66 aa)1HATPase_c: 473-590 aa (118 aa)2Response_reg: 609-713 aa (105 aa)3Response_reg: 752-867 aa (116 aa)4
Domain-by-domain annotation4 items
1 HisKA#1
359-424 aa · 66 aa · 7.5% of protein
Raw tokenHisKA:359:0.00000000000000708:424:66:64
2 HATPase_c#2
473-590 aa · 118 aa · 13.5% of protein
Raw tokenHATPase_c:473:4.88e-30:590:118:109
3 Response_reg#3
609-713 aa · 105 aa · 12.0% of protein
Raw tokenResponse_reg:609:5.71e-23:713:105:111
4 Response_reg#4
752-867 aa · 116 aa · 13.2% of protein
Raw tokenResponse_reg:752:4.97e-24:867:116:111
  • Raw architecture: HisKA:359:0.00000000000000708:424:66:64#HATPase_c:473:4.88e-30:590:118:109#Response_reg:609:5.71e-23:713:105:111#Response_reg:752:4.97e-24:867:116:111
  • Domain description: 1 HisKA,1 HATPase_c,2 Response_reg
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labeltriadGCF_024460865::NZ_JANFZG010000014.1::G00007
Group size33 locus tags listed below.
HK / RR2 / 1Counts resolved for the local TCS neighborhood.
Context span10618-19681Genomic interval covered by the local TCS group.
Identifiers
Old locus tagNE546_07865RefSeq proteinWP_066862721.1
Context group IDGCF_024460865::NZ_JANFZG010000014.1::G00007
Context members
NE546_RS07865NE546_RS07870NE546_RS07880
Partner locus tags
NE546_RS07865NE546_RS07870NE546_RS07880
Partner old locus tags
NE546_07865NE546_07870NE546_07880

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_066862721.1Primary protein accession used for annex mappings.
UniProt accessionA0ABT1RYJ6Primary UniProt accession resolved in the annex database.
UniProt IDA0ABT1RYJ6_9FIRMDisplay identifier provided by UniProt.
GO / PubMed0 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagNE546_RS07865Primary locus identifier stored in the genes table.
Old locus tagNE546_07865Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JANFZG010000014.1Sequence record reported by the local genomic context database.
Genomic interval10 618-13 248 nt2 631 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span10 618-19 681 ntGCF_024460865::NZ_JANFZG010000014.1::G00007

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_024460865::NZ_JANFZG010000014.1::G00007

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labeltriadNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JANFZG010000014.1All displayed genes belong to this local TCS context.
Neighborhood span10 618-19 681 nt9 064 nt
Members31 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
10 618 nt19 681 nt
Neighborhood gene cards

3 genes in the current local neighborhood.

NE546_RS07865GCF_024460865#NE546_RS07865
HKHybridCurrent focus

10 618-13 248 nt · Reverse (-)

Old locus NE546_07865RefSeq WP_066862721.1
NE546_RS07870GCF_024460865#NE546_RS07870
HKHybrid

13 322-17 599 nt · Reverse (-)

Old locus NE546_07870RefSeq WP_074039117.1
NE546_RS07880GCF_024460865#NE546_RS07880
RRPleD_VieA

18 002-19 681 nt · Reverse (-)

Old locus NE546_07880RefSeq WP_338086348.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0452606Run 6 · HK · 5 sequences
Representative sequenceGCF_024460865#NE546_RS07865The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c + Response_reg + Response_reg4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0452606

Simplified PFAM architecture for HKOC_0452606

PFAM domain coverage: 414 / 876 aa (47.3%)

1 aa876 aa
HisKA: 359-424 aaHisKAHATPase_c: 473-589 aaHATPase_cResponse_reg: 609-723 aaResponse_regResponse_reg: 752-867 aaResponse_reg
HisKAHATPase_cResponse_regResponse_reg
  • Simplified architecture: HisKA + HATPase_c + Response_reg + Response_reg
  • Raw architecture: HisKA[359-424] | HATPase_c[473-589] | Response_reg[609-723] | Response_reg[752-867]
  • Domain count: 4
  • Matched identifier: HKOC_0452606
  • Positioned domains: HisKA 359-424 ; HATPase_c 473-589 ; Response_reg 609-723 ; Response_reg 752-867
Cluster members and taxonomy
Visualization

Representative gene: GCF_024460865#NE546_RS07865

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 776 382 · GCF_024460865
AssemblyASM2446086v1 · Contighaploid
Genome composition4 030 546 bp · 52,5% GCNeglectibacter timonensis
Signal transduction countsGenes 113 · HK 57 · RR 53CheA 0 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyOscillospiraceaeGenusNeglectibacter
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Oscillospiraceae7Neglectibacter

Related genes

Preview from the same derived genome key