1 HAMP#1
279-349 aa · 71 aa · 12.3% of protein
Raw token
HAMP:279:0.000000509:349:71:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
NE546_RS07365
Histidine kinase, Classic
Neglectibacter timonensis · GCF_024460865
ClassHKTypeClassicLength576 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_024460865#NE546_RS07365Stable P2CS identifier used across views.
GenomeGCF_024460865Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae; Neglectibacter
Domain signature
Compact overview inferred from the domain field
HAMPHis_kinaseHATPase_c
Protein length576 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage267 / 576 aa (46.4%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa576 aa
Domain-by-domain annotation3 items
2 His_kinase#2
366-444 aa · 79 aa · 13.7% of protein
Raw token
His_kinase:366:1.01e-23:444:79:803 HATPase_c#3
460-576 aa · 117 aa · 20.3% of protein
Raw token
HATPase_c:460:0.00000000169:576:118:109- Raw architecture: HAMP:279:0.000000509:349:71:69#His_kinase:366:1.01e-23:444:79:80#HATPase_c:460:0.00000000169:576:118:109
- Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_024460865::NZ_JANFZG010000012.1::G00005
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span74454-77728Genomic interval covered by the local TCS group.
Identifiers
Old locus tagNE546_07365RefSeq proteinWP_256191708.1
Context group ID
GCF_024460865::NZ_JANFZG010000012.1::G00005Context members
NE546_RS07360NE546_RS07365
Partner locus tags
NE546_RS07360NE546_RS07365
Partner old locus tags
NE546_07360NE546_07365
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_256191708.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagNE546_RS07365Primary locus identifier stored in the genes table.
Old locus tagNE546_07365Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JANFZG010000012.1Sequence record reported by the local genomic context database.
Genomic interval75 998-77 728 nt1 731 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span74 454-77 728 ntGCF_024460865::NZ_JANFZG010000012.1::G00005
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_024460865::NZ_JANFZG010000012.1::G00005Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JANFZG010000012.1All displayed genes belong to this local TCS context.
Neighborhood span74 454-77 728 nt3 275 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
74 454 nt77 728 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
NE546_RS07360GCF_024460865#NE546_RS07360
RRunclassified
74 454-75 980 nt · Reverse (-)
NE546_RS07365GCF_024460865#NE546_RS07365
HKClassicCurrent focus
75 998-77 728 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_024460865#NE546_RS07365The current gene is the representative for this cluster.
PFAM architectureHis_kinase + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1185779
Simplified PFAM architecture for HKOC_1185779
PFAM domain coverage: 194 / 576 aa (33.7%)
1 aa576 aa
His_kinaseHATPase_c
- Simplified architecture: His_kinase + HATPase_c
- Raw architecture: His_kinase[366-443] | HATPase_c[460-575]
- Domain count: 2
- Matched identifier: HKOC_1185779
- Positioned domains: His_kinase 366-443 ; HATPase_c 460-575
Cluster members and taxonomy
Representative gene: GCF_024460865#NE546_RS07365
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 776 382 · GCF_024460865
AssemblyASM2446086v1 · Contighaploid
Genome composition4 030 546 bp · 52,5% GCNeglectibacter timonensis
Signal transduction countsGenes 113 · HK 57 · RR 53CheA 0 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyOscillospiraceaeGenusNeglectibacter
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Oscillospiraceae7Neglectibacter
Related genes
Preview from the same derived genome key