Gene detail

NE546_RS06835

Histidine kinase, Classic

Neglectibacter timonensis · GCF_024460865

ClassHKTypeClassicLength594 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_024460865#NE546_RS06835Stable P2CS identifier used across views.
GenomeGCF_024460865Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae; Neglectibacter
Selected clusterHKOC_1090384Run 6 · 6 sequences · id 100% · cov 80% · representative
External referencesWP_082942222.1 · A0ABT1RXN8 · MIST4 NE546_RS06835RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHis_kinaseHATPase_c
Protein length594 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage256 / 594 aa (43.1%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa594 aa
HAMP: 296-365 aa (70 aa)1His_kinase: 380-459 aa (80 aa)2HATPase_c: 475-580 aa (106 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
296-365 aa · 70 aa · 11.8% of protein
Raw tokenHAMP:296:0.00000000669:365:70:69
2 His_kinase#2
380-459 aa · 80 aa · 13.5% of protein
Raw tokenHis_kinase:380:1.98e-31:459:80:80
3 HATPase_c#3
475-580 aa · 106 aa · 17.8% of protein
Raw tokenHATPase_c:475:0.0000000000000282:580:110:109
  • Raw architecture: HAMP:296:0.00000000669:365:70:69#His_kinase:380:1.98e-31:459:80:80#HATPase_c:475:0.0000000000000282:580:110:109
  • Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_024460865::NZ_JANFZG010000011.1::G00003
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span71358-74689Genomic interval covered by the local TCS group.
Identifiers
Old locus tagNE546_06835RefSeq proteinWP_082942222.1
Context group IDGCF_024460865::NZ_JANFZG010000011.1::G00003
Context members
NE546_RS06835NE546_RS06840
Partner locus tags
NE546_RS06835NE546_RS06840
Partner old locus tags
NE546_06835NE546_06840
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_082942222.1Primary protein accession used for annex mappings.
UniProt accessionA0ABT1RXN8Primary UniProt accession resolved in the annex database.
UniProt IDA0ABT1RXN8_9FIRMDisplay identifier provided by UniProt.
GO / PubMed1 / 0Unique GO terms and literature references available below.
GO terms

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagNE546_RS06835Primary locus identifier stored in the genes table.
Old locus tagNE546_06835Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JANFZG010000011.1Sequence record reported by the local genomic context database.
Genomic interval71 358-73 142 nt1 785 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span71 358-74 689 ntGCF_024460865::NZ_JANFZG010000011.1::G00003

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_024460865::NZ_JANFZG010000011.1::G00003

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JANFZG010000011.1All displayed genes belong to this local TCS context.
Neighborhood span71 358-74 689 nt3 332 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
71 358 nt74 689 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

NE546_RS06835GCF_024460865#NE546_RS06835
HKClassicCurrent focus

71 358-73 142 nt · Reverse (-)

Old locus NE546_06835RefSeq WP_082942222.1
NE546_RS06840GCF_024460865#NE546_RS06840
RRunclassified

73 139-74 689 nt · Reverse (-)

Old locus NE546_06840RefSeq WP_066864796.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1090384Run 6 · HK · 6 sequences
Representative sequenceGCF_024460865#NE546_RS06835The current gene is the representative for this cluster.
PFAM architectureHis_kinase + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1090384

Simplified PFAM architecture for HKOC_1090384

PFAM domain coverage: 185 / 594 aa (31.1%)

1 aa594 aa
His_kinase: 380-458 aaHis_kinaseHATPase_c: 475-580 aaHATPase_c
His_kinaseHATPase_c
  • Simplified architecture: His_kinase + HATPase_c
  • Raw architecture: His_kinase[380-458] | HATPase_c[475-580]
  • Domain count: 2
  • Matched identifier: HKOC_1090384
  • Positioned domains: His_kinase 380-458 ; HATPase_c 475-580
Cluster members and taxonomy
Visualization

Representative gene: GCF_024460865#NE546_RS06835

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 776 382 · GCF_024460865
AssemblyASM2446086v1 · Contighaploid
Genome composition4 030 546 bp · 52,5% GCNeglectibacter timonensis
Signal transduction countsGenes 113 · HK 57 · RR 53CheA 0 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyOscillospiraceaeGenusNeglectibacter
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Oscillospiraceae7Neglectibacter

Related genes

Preview from the same derived genome key