1 His_kinase#1
237-316 aa · 80 aa · 18.6% of protein
Raw token
His_kinase:237:4.17e-25:316:81:80P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
NE546_RS04130
Histidine kinase, Classic
Neglectibacter timonensis · GCF_024460865
ClassHKTypeClassicLength431 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_024460865#NE546_RS04130Stable P2CS identifier used across views.
GenomeGCF_024460865Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae; Neglectibacter
Domain signature
Compact overview inferred from the domain field
His_kinaseHATPase_c
Protein length431 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage172 / 431 aa (39.9%)Merged over positioned domains only.
Domain description1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa431 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
337-428 aa · 92 aa · 21.3% of protein
Raw token
HATPase_c:337:0.000000000000467:428:103:109- Raw architecture: His_kinase:237:4.17e-25:316:81:80#HATPase_c:337:0.000000000000467:428:103:109
- Domain description: 1 His_kinase,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_024460865::NZ_JANFZG010000006.1::G00048
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span81363-83440Genomic interval covered by the local TCS group.
Identifiers
Old locus tagNE546_04125RefSeq proteinWP_066861707.1
Context group ID
GCF_024460865::NZ_JANFZG010000006.1::G00048Context members
NE546_RS04125NE546_RS04130
Partner locus tags
NE546_RS04125NE546_RS04130
Partner old locus tags
NE546_04120NE546_04125
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_066861707.1Primary protein accession used for annex mappings.
UniProt accessionA0ABT1RVZ5Primary UniProt accession resolved in the annex database.
UniProt IDA0ABT1RVZ5_9FIRMDisplay identifier provided by UniProt.
GO / PubMed1 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagNE546_RS04130Primary locus identifier stored in the genes table.
Old locus tagNE546_04125Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JANFZG010000006.1Sequence record reported by the local genomic context database.
Genomic interval82 145-83 440 nt1 296 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span81 363-83 440 ntGCF_024460865::NZ_JANFZG010000006.1::G00048
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_024460865::NZ_JANFZG010000006.1::G00048Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JANFZG010000006.1All displayed genes belong to this local TCS context.
Neighborhood span81 363-83 440 nt2 078 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
81 363 nt83 440 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
NE546_RS04125GCF_024460865#NE546_RS04125
RRunclassified
81 363-82 148 nt · Reverse (-)
NE546_RS04130GCF_024460865#NE546_RS04130
HKClassicCurrent focus
82 145-83 440 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_024460865#NE546_RS04130The current gene is the representative for this cluster.
PFAM architectureHis_kinase + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2166997
Simplified PFAM architecture for HKOC_2166997
PFAM domain coverage: 172 / 431 aa (39.9%)
1 aa431 aa
His_kinaseHATPase_c
- Simplified architecture: His_kinase + HATPase_c
- Raw architecture: His_kinase[238-316] | HATPase_c[335-427]
- Domain count: 2
- Matched identifier: HKOC_2166997
- Positioned domains: His_kinase 238-316 ; HATPase_c 335-427
Cluster members and taxonomy
Representative gene: GCF_024460865#NE546_RS04130
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 776 382 · GCF_024460865
AssemblyASM2446086v1 · Contighaploid
Genome composition4 030 546 bp · 52,5% GCNeglectibacter timonensis
Signal transduction countsGenes 113 · HK 57 · RR 53CheA 0 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyOscillospiraceaeGenusNeglectibacter
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Oscillospiraceae7Neglectibacter
Related genes
Preview from the same derived genome key