Gene detail

NE546_RS03475

Histidine kinase, Classic

Neglectibacter timonensis · GCF_024460865

ClassHKTypeClassicLength599 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_024460865#NE546_RS03475Stable P2CS identifier used across views.
GenomeGCF_024460865Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae; Neglectibacter
Selected clusterHKOC_1059771Run 6 · 6 sequences · id 100% · cov 80% · representative
External referencesWP_066860449.1 · A0ABT1RYG6 · MIST4 NE546_RS03475RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHis_kinaseHATPase_c
Protein length599 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage247 / 599 aa (41.2%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa599 aa
HAMP: 306-375 aa (70 aa)1His_kinase: 392-469 aa (78 aa)2HATPase_c: 488-586 aa (99 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
306-375 aa · 70 aa · 11.7% of protein
Raw tokenHAMP:306:0.000000000145:375:70:69
2 His_kinase#2
392-469 aa · 78 aa · 13.0% of protein
Raw tokenHis_kinase:392:1.41e-28:469:78:80
3 HATPase_c#3
488-586 aa · 99 aa · 16.5% of protein
Raw tokenHATPase_c:488:0.00000000000135:586:105:109
  • Raw architecture: HAMP:306:0.000000000145:375:70:69#His_kinase:392:1.41e-28:469:78:80#HATPase_c:488:0.00000000000135:586:105:109
  • Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_024460865::NZ_JANFZG010000005.1::G00044
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span77194-79723Genomic interval covered by the local TCS group.
Identifiers
Old locus tagNE546_03475RefSeq proteinWP_066860449.1
Context group IDGCF_024460865::NZ_JANFZG010000005.1::G00044
Context members
NE546_RS03475NE546_RS03480
Partner locus tags
NE546_RS03475NE546_RS03480
Partner old locus tags
NE546_03475NE546_03480
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_066860449.1Primary protein accession used for annex mappings.
UniProt accessionA0ABT1RYG6Primary UniProt accession resolved in the annex database.
UniProt IDA0ABT1RYG6_9FIRMDisplay identifier provided by UniProt.
GO / PubMed1 / 0Unique GO terms and literature references available below.
GO terms

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagNE546_RS03475Primary locus identifier stored in the genes table.
Old locus tagNE546_03475Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JANFZG010000005.1Sequence record reported by the local genomic context database.
Genomic interval77 194-78 993 nt1 800 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span77 194-79 723 ntGCF_024460865::NZ_JANFZG010000005.1::G00044

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_024460865::NZ_JANFZG010000005.1::G00044

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JANFZG010000005.1All displayed genes belong to this local TCS context.
Neighborhood span77 194-79 723 nt2 530 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
77 194 nt79 723 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

NE546_RS03475GCF_024460865#NE546_RS03475
HKClassicCurrent focus

77 194-78 993 nt · Reverse (-)

Old locus NE546_03475RefSeq WP_066860449.1
NE546_RS03480GCF_024460865#NE546_RS03480
RRunclassified

78 983-79 723 nt · Reverse (-)

Old locus NE546_03480RefSeq WP_256191745.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1059771Run 6 · HK · 6 sequences
Representative sequenceGCF_024460865#NE546_RS03475The current gene is the representative for this cluster.
PFAM architectureHAMP + His_kinase + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1059771

Simplified PFAM architecture for HKOC_1059771

PFAM domain coverage: 227 / 599 aa (37.9%)

1 aa599 aa
HAMP: 324-374 aaHAMPHis_kinase: 392-468 aaHis_kinaseHATPase_c: 488-586 aaHATPase_c
HAMPHis_kinaseHATPase_c
  • Simplified architecture: HAMP + His_kinase + HATPase_c
  • Raw architecture: HAMP[324-374] | His_kinase[392-468] | HATPase_c[488-586]
  • Domain count: 3
  • Matched identifier: HKOC_1059771
  • Positioned domains: HAMP 324-374 ; His_kinase 392-468 ; HATPase_c 488-586
Cluster members and taxonomy
Visualization

Representative gene: GCF_024460865#NE546_RS03475

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 776 382 · GCF_024460865
AssemblyASM2446086v1 · Contighaploid
Genome composition4 030 546 bp · 52,5% GCNeglectibacter timonensis
Signal transduction countsGenes 113 · HK 57 · RR 53CheA 0 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyOscillospiraceaeGenusNeglectibacter
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Oscillospiraceae7Neglectibacter

Related genes

Preview from the same derived genome key