Gene detail

NE546_RS02005

Histidine kinase, Classic

Neglectibacter timonensis · GCF_024460865

ClassHKTypeClassicLength614 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_024460865#NE546_RS02005Stable P2CS identifier used across views.
GenomeGCF_024460865Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae; Neglectibacter
Selected clusterHKOC_0992684Run 6 · 2 sequences · id 100% · cov 80% · representative
External referencesWP_256191657.1 · MIST4 NE546_RS02005RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

dCache_1HAMPHis_kinaseHATPase_c
Protein length614 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage385 / 614 aa (62.7%)Merged over positioned domains only.
Domain description1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa614 aa
dCache_1: 153-273 aa (121 aa)1HAMP: 292-363 aa (72 aa)2His_kinase: 378-456 aa (79 aa)3HATPase_c: 472-584 aa (113 aa)4
Domain-by-domain annotation4 items
1 dCache_1#1
153-273 aa · 121 aa · 19.7% of protein
Raw tokendCache_1:153:0.0000164:273:123:195
2 HAMP#2
292-363 aa · 72 aa · 11.7% of protein
Raw tokenHAMP:292:0.000000000000419:363:72:69
3 His_kinase#3
378-456 aa · 79 aa · 12.9% of protein
Raw tokenHis_kinase:378:1.01e-28:456:80:80
4 HATPase_c#4
472-584 aa · 113 aa · 18.4% of protein
Raw tokenHATPase_c:472:0.000000000000601:584:113:109
  • Raw architecture: dCache_1:153:0.0000164:273:123:195#HAMP:292:0.000000000000419:363:72:69#His_kinase:378:1.01e-28:456:80:80#HATPase_c:472:0.000000000000601:584:113:109
  • Domain description: 1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_024460865::NZ_JANFZG010000003.1::G00030
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span83502-86996Genomic interval covered by the local TCS group.
Identifiers
Old locus tagNE546_02000RefSeq proteinWP_256191657.1
Context group IDGCF_024460865::NZ_JANFZG010000003.1::G00030
Context members
NE546_RS02005NE546_RS02010
Partner locus tags
NE546_RS02005NE546_RS02010
Partner old locus tags
NE546_02000NE546_02005
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_256191657.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagNE546_RS02005Primary locus identifier stored in the genes table.
Old locus tagNE546_02000Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JANFZG010000003.1Sequence record reported by the local genomic context database.
Genomic interval83 502-85 346 nt1 845 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span83 502-86 996 ntGCF_024460865::NZ_JANFZG010000003.1::G00030

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_024460865::NZ_JANFZG010000003.1::G00030

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JANFZG010000003.1All displayed genes belong to this local TCS context.
Neighborhood span83 502-86 996 nt3 495 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
83 502 nt86 996 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

NE546_RS02005GCF_024460865#NE546_RS02005
HKClassicCurrent focus

83 502-85 346 nt · Forward (+)

Old locus NE546_02000RefSeq WP_256191657.1
NE546_RS02010GCF_024460865#NE546_RS02010
RRunclassified

85 434-86 996 nt · Forward (+)

Old locus NE546_02005RefSeq WP_256191658.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0992684Run 6 · HK · 2 sequences
Representative sequenceGCF_024460865#NE546_RS02005The current gene is the representative for this cluster.
PFAM architectureHis_kinase + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0992684

Simplified PFAM architecture for HKOC_0992684

PFAM domain coverage: 191 / 614 aa (31.1%)

1 aa614 aa
His_kinase: 378-456 aaHis_kinaseHATPase_c: 473-584 aaHATPase_c
His_kinaseHATPase_c
  • Simplified architecture: His_kinase + HATPase_c
  • Raw architecture: His_kinase[378-456] | HATPase_c[473-584]
  • Domain count: 2
  • Matched identifier: HKOC_0992684
  • Positioned domains: His_kinase 378-456 ; HATPase_c 473-584
Cluster members and taxonomy
Visualization

Representative gene: GCF_024460865#NE546_RS02005

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 776 382 · GCF_024460865
AssemblyASM2446086v1 · Contighaploid
Genome composition4 030 546 bp · 52,5% GCNeglectibacter timonensis
Signal transduction countsGenes 113 · HK 57 · RR 53CheA 0 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyOscillospiraceaeGenusNeglectibacter
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Oscillospiraceae7Neglectibacter

Related genes

Preview from the same derived genome key