Gene detail

DW904_RS00525

Histidine kinase, Classic

Ruminococcus sp. AM42-11 · GCF_003480145

ClassHKTypeClassicLength601 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003480145#DW904_RS00525Stable P2CS identifier used across views.
GenomeGCF_003480145Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae; Ruminococcus
Selected clusterHKOC_1048758Run 6 · 18 sequences · id 100% · cov 80% · representative
External referencesWP_118577629.1 · MIST4 DW904_RS00525RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

dCache_1HAMPHis_kinaseHATPase_c
Protein length601 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage495 / 601 aa (82.4%)Merged over positioned domains only.
Domain description1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa601 aa
dCache_1: 42-278 aa (237 aa)1HAMP: 296-364 aa (69 aa)2His_kinase: 380-458 aa (79 aa)3HATPase_c: 477-586 aa (110 aa)4
Domain-by-domain annotation4 items
1 dCache_1#1
42-278 aa · 237 aa · 39.4% of protein
Raw tokendCache_1:42:0.0000000000468:278:243:195
2 HAMP#2
296-364 aa · 69 aa · 11.5% of protein
Raw tokenHAMP:296:0.00000000000000364:364:69:69
3 His_kinase#3
380-458 aa · 79 aa · 13.1% of protein
Raw tokenHis_kinase:380:4.86e-34:458:79:80
4 HATPase_c#4
477-586 aa · 110 aa · 18.3% of protein
Raw tokenHATPase_c:477:0.00000000114:586:111:109
  • Raw architecture: dCache_1:42:0.0000000000468:278:243:195#HAMP:296:0.00000000000000364:364:69:69#His_kinase:380:4.86e-34:458:79:80#HATPase_c:477:0.00000000114:586:111:109
  • Domain description: 1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_003480145::NZ_QUIO01000001.1::G00005
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span119596-122986Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDW904_00525RefSeq proteinWP_118577629.1
Context group IDGCF_003480145::NZ_QUIO01000001.1::G00005
Context members
DW904_RS00520DW904_RS00525
Partner locus tags
DW904_RS00520DW904_RS00525
Partner old locus tags
DW904_00520DW904_00525
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_118577629.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagDW904_RS00525Primary locus identifier stored in the genes table.
Old locus tagDW904_00525Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_QUIO01000001.1Sequence record reported by the local genomic context database.
Genomic interval121 181-122 986 nt1 806 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span119 596-122 986 ntGCF_003480145::NZ_QUIO01000001.1::G00005

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_003480145::NZ_QUIO01000001.1::G00005

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_QUIO01000001.1All displayed genes belong to this local TCS context.
Neighborhood span119 596-122 986 nt3 391 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
119 596 nt122 986 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

DW904_RS00520GCF_003480145#DW904_RS00520
RRunclassified

119 596-121 209 nt · Reverse (-)

Old locus DW904_00520RefSeq WP_118577628.1
DW904_RS00525GCF_003480145#DW904_RS00525
HKClassicCurrent focus

121 181-122 986 nt · Reverse (-)

Old locus DW904_00525RefSeq WP_118577629.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1048758Run 6 · HK · 18 sequences
Representative sequenceGCF_003480145#DW904_RS00525The current gene is the representative for this cluster.
PFAM architectureHAMP + His_kinase + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1048758

Simplified PFAM architecture for HKOC_1048758

PFAM domain coverage: 240 / 601 aa (39.9%)

1 aa601 aa
HAMP: 313-363 aaHAMPHis_kinase: 380-458 aaHis_kinaseHATPase_c: 476-585 aaHATPase_c
HAMPHis_kinaseHATPase_c
  • Simplified architecture: HAMP + His_kinase + HATPase_c
  • Raw architecture: HAMP[313-363] | His_kinase[380-458] | HATPase_c[476-585]
  • Domain count: 3
  • Matched identifier: HKOC_1048758
  • Positioned domains: HAMP 313-363 ; His_kinase 380-458 ; HATPase_c 476-585
Cluster members and taxonomy
Visualization

Representative gene: GCF_003480145#DW904_RS00525

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 2 292 372 · GCF_003480145
AssemblyASM348014v1 · Contighaploid
Genome composition4 698 861 bp · 42,5% GCRuminococcus sp. AM42-11
Signal transduction countsGenes 130 · HK 64 · RR 63CheA 0 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyOscillospiraceaeGenusRuminococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Oscillospiraceae7Ruminococcus

Related genes

Preview from the same derived genome key