Gene detail

DXD18_RS05495

Histidine kinase, Classic

Dorea formicigenerans · GCF_003437485

ClassHKTypeClassicLength612 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003437485#DXD18_RS05495Stable P2CS identifier used across views.
GenomeGCF_003437485Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Dorea
Selected clusterHKOC_0998059Run 6 · 6 sequences · id 100% · cov 80% · representative
External referencesWP_117657283.1 · A0A415N2S6 · MIST4 DXD18_RS05495RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

dCache_1His_kinaseHATPase_c
Protein length612 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage389 / 612 aa (63.6%)Merged over positioned domains only.
Domain description1 dCache_1,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa612 aa
dCache_1: 83-283 aa (201 aa)1His_kinase: 383-462 aa (80 aa)2HATPase_c: 478-585 aa (108 aa)3
Domain-by-domain annotation3 items
1 dCache_1#1
83-283 aa · 201 aa · 32.8% of protein
Raw tokendCache_1:83:0.000000000000413:283:206:195
2 His_kinase#2
383-462 aa · 80 aa · 13.1% of protein
Raw tokenHis_kinase:383:2.42e-32:462:80:80
3 HATPase_c#3
478-585 aa · 108 aa · 17.6% of protein
Raw tokenHATPase_c:478:1.29e-16:585:111:109
  • Raw architecture: dCache_1:83:0.000000000000413:283:206:195#His_kinase:383:2.42e-32:462:80:80#HATPase_c:478:1.29e-16:585:111:109
  • Domain description: 1 dCache_1,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_003437485::NZ_QSQM01000002.1::G00031
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span272131-275579Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDXD18_05485RefSeq proteinWP_117657283.1
Context group IDGCF_003437485::NZ_QSQM01000002.1::G00031
Context members
DXD18_RS05490DXD18_RS05495
Partner locus tags
DXD18_RS05490DXD18_RS05495
Partner old locus tags
DXD18_05480DXD18_05485
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_117657283.1Primary protein accession used for annex mappings.
UniProt accessionA0A415N2S6Primary UniProt accession resolved in the annex database.
UniProt IDA0A415N2S6_9FIRMDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagDXD18_RS05495Primary locus identifier stored in the genes table.
Old locus tagDXD18_05485Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_QSQM01000002.1Sequence record reported by the local genomic context database.
Genomic interval273 741-275 579 nt1 839 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span272 131-275 579 ntGCF_003437485::NZ_QSQM01000002.1::G00031

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_003437485::NZ_QSQM01000002.1::G00031

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_QSQM01000002.1All displayed genes belong to this local TCS context.
Neighborhood span272 131-275 579 nt3 449 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
272 131 nt275 579 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

DXD18_RS05490GCF_003437485#DXD18_RS05490
RRunclassified

272 131-273 735 nt · Forward (+)

Old locus DXD18_05480RefSeq WP_117657282.1
DXD18_RS05495GCF_003437485#DXD18_RS05495
HKClassicCurrent focus

273 741-275 579 nt · Forward (+)

Old locus DXD18_05485RefSeq WP_117657283.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0998059Run 6 · HK · 6 sequences
Representative sequenceGCF_003437485#DXD18_RS05495The current gene is the representative for this cluster.
PFAM architecturedCache_1 + His_kinase + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0998059

Simplified PFAM architecture for HKOC_0998059

PFAM domain coverage: 419 / 612 aa (68.5%)

1 aa612 aa
dCache_1: 52-282 aadCache_1His_kinase: 383-462 aaHis_kinaseHATPase_c: 479-586 aaHATPase_c
dCache_1His_kinaseHATPase_c
  • Simplified architecture: dCache_1 + His_kinase + HATPase_c
  • Raw architecture: dCache_1[52-282] | His_kinase[383-462] | HATPase_c[479-586]
  • Domain count: 3
  • Matched identifier: HKOC_0998059
  • Positioned domains: dCache_1 52-282 ; His_kinase 383-462 ; HATPase_c 479-586
Cluster members and taxonomy
Visualization

Representative gene: GCF_003437485#DXD18_RS05495

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 39 486 · GCF_003437485
AssemblyASM343748v1 · Scaffoldhaploid
Genome composition2 865 423 bp · 41,0% GCDorea formicigenerans
Signal transduction countsGenes 84 · HK 41 · RR 41CheA 0 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusDorea
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Dorea

Related genes

Preview from the same derived genome key