Gene detail

DXD18_RS01400

Histidine kinase, Classic

Dorea formicigenerans · GCF_003437485

ClassHKTypeClassicLength592 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003437485#DXD18_RS01400Stable P2CS identifier used across views.
GenomeGCF_003437485Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Dorea
Selected clusterHKOC_1100578Run 6 · 4 sequences · id 100% · cov 80% · representative
External referencesWP_117656943.1 · A0A415HAI5 · MIST4 DXD18_RS01400RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHis_kinaseHATPase_c
Protein length592 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage263 / 592 aa (44.4%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa592 aa
HAMP: 294-363 aa (70 aa)1His_kinase: 378-457 aa (80 aa)2HATPase_c: 473-585 aa (113 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
294-363 aa · 70 aa · 11.8% of protein
Raw tokenHAMP:294:0.000000000000146:363:70:69
2 His_kinase#2
378-457 aa · 80 aa · 13.5% of protein
Raw tokenHis_kinase:378:5.18e-33:457:80:80
3 HATPase_c#3
473-585 aa · 113 aa · 19.1% of protein
Raw tokenHATPase_c:473:0.000000000737:585:114:109
  • Raw architecture: HAMP:294:0.000000000000146:363:70:69#His_kinase:378:5.18e-33:457:80:80#HATPase_c:473:0.000000000737:585:114:109
  • Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_003437485::NZ_QSQM01000001.1::G00004
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span302403-305776Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDXD18_01395RefSeq proteinWP_117656943.1
Context group IDGCF_003437485::NZ_QSQM01000001.1::G00004
Context members
DXD18_RS01395DXD18_RS01400
Partner locus tags
DXD18_RS01395DXD18_RS01400
Partner old locus tags
DXD18_01390DXD18_01395
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_117656943.1Primary protein accession used for annex mappings.
UniProt accessionA0A415HAI5Primary UniProt accession resolved in the annex database.
UniProt IDA0A415HAI5_9FIRMDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagDXD18_RS01400Primary locus identifier stored in the genes table.
Old locus tagDXD18_01395Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_QSQM01000001.1Sequence record reported by the local genomic context database.
Genomic interval303 998-305 776 nt1 779 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span302 403-305 776 ntGCF_003437485::NZ_QSQM01000001.1::G00004

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_003437485::NZ_QSQM01000001.1::G00004

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_QSQM01000001.1All displayed genes belong to this local TCS context.
Neighborhood span302 403-305 776 nt3 374 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
302 403 nt305 776 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

DXD18_RS01395GCF_003437485#DXD18_RS01395
RRunclassified

302 403-304 001 nt · Forward (+)

Old locus DXD18_01390RefSeq WP_117656942.1
DXD18_RS01400GCF_003437485#DXD18_RS01400
HKClassicCurrent focus

303 998-305 776 nt · Forward (+)

Old locus DXD18_01395RefSeq WP_117656943.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1100578Run 6 · HK · 4 sequences
Representative sequenceGCF_003437485#DXD18_RS01400The current gene is the representative for this cluster.
PFAM architectureHAMP + His_kinase + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1100578

Simplified PFAM architecture for HKOC_1100578

PFAM domain coverage: 245 / 592 aa (41.4%)

1 aa592 aa
HAMP: 311-363 aaHAMPHis_kinase: 379-455 aaHis_kinaseHATPase_c: 472-586 aaHATPase_c
HAMPHis_kinaseHATPase_c
  • Simplified architecture: HAMP + His_kinase + HATPase_c
  • Raw architecture: HAMP[311-363] | His_kinase[379-455] | HATPase_c[472-586]
  • Domain count: 3
  • Matched identifier: HKOC_1100578
  • Positioned domains: HAMP 311-363 ; His_kinase 379-455 ; HATPase_c 472-586
Cluster members and taxonomy
Visualization

Representative gene: GCF_003437485#DXD18_RS01400

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 39 486 · GCF_003437485
AssemblyASM343748v1 · Scaffoldhaploid
Genome composition2 865 423 bp · 41,0% GCDorea formicigenerans
Signal transduction countsGenes 84 · HK 41 · RR 41CheA 0 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusDorea
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Dorea

Related genes

Preview from the same derived genome key