Gene detail

ECAD30_RS17475

Histidine kinase, Classic

Escherichia coli AD30 · GCF_000304255

ClassHKTypeClassicLength449 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000304255#ECAD30_RS17475Stable P2CS identifier used across views.
GenomeGCF_000304255Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Selected clusterHKOC_1906009Run 6 · 10119 sequences · id 100% · cov 80%
External referencesWP_000673402.1 · A0AAN3ZL26 · MIST4 ECAD30_RS17475RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length449 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage228 / 449 aa (50.8%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa449 aa
HAMP: 164-232 aa (69 aa)1HisKA: 238-301 aa (64 aa)2HATPase_c: 348-442 aa (95 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
164-232 aa · 69 aa · 15.4% of protein
Raw tokenHAMP:164:0.00000155:232:70:69
2 HisKA#2
238-301 aa · 64 aa · 14.3% of protein
Raw tokenHisKA:238:0.00000000000525:301:64:64
3 HATPase_c#3
348-442 aa · 95 aa · 21.2% of protein
Raw tokenHATPase_c:348:1.13e-25:442:99:109
  • Raw architecture: HAMP:164:0.00000155:232:70:69#HisKA:238:0.00000000000525:301:64:64#HATPase_c:348:1.13e-25:442:99:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000304255::NZ_AMSK01000003.1::G00012
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span251156-253161Genomic interval covered by the local TCS group.
Identifiers
Old locus tagECAD30_11320RefSeq proteinWP_000673402.1
Context group IDGCF_000304255::NZ_AMSK01000003.1::G00012
Context members
ECAD30_RS17475ECAD30_RS17470
Partner locus tags
ECAD30_RS17475ECAD30_RS17470
Partner old locus tags
ECAD30_11320ECAD30_11330
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_000673402.1Primary protein accession used for annex mappings.
UniProt accessionA0AAN3ZL26Primary UniProt accession resolved in the annex database.
UniProt IDA0AAN3ZL26_SHIDYDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagECAD30_RS17475Primary locus identifier stored in the genes table.
Old locus tagECAD30_11320Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AMSK01000003.1Sequence record reported by the local genomic context database.
Genomic interval251 156-252 505 nt1 350 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span251 156-253 161 ntGCF_000304255::NZ_AMSK01000003.1::G00012

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000304255::NZ_AMSK01000003.1::G00012

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AMSK01000003.1All displayed genes belong to this local TCS context.
Neighborhood span251 156-253 161 nt2 006 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
251 156 nt253 161 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

ECAD30_RS17475GCF_000304255#ECAD30_RS17475
HKClassicCurrent focus

251 156-252 505 nt · Reverse (-)

Old locus ECAD30_11320RefSeq WP_000673402.1
ECAD30_RS17470GCF_000304255#ECAD30_RS17470
RROmpR

252 502-253 161 nt · Reverse (-)

Old locus ECAD30_11330RefSeq WP_001221493.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1906009Run 6 · HK · 10119 sequences
Representative sequenceGCF_022396775#LCT52_RS05405Use this link to inspect the representative gene detail.
PFAM architecture2CSK_N + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1906009

Simplified PFAM architecture for HKOC_1906009

PFAM domain coverage: 299 / 455 aa (65.7%)

1 aa455 aa
2CSK_N: 23-157 aa2CSK_NHisKA: 237-301 aaHisKAHATPase_c: 349-447 aaHATPase_c
2CSK_NHisKAHATPase_c
  • Simplified architecture: 2CSK_N + HisKA + HATPase_c
  • Raw architecture: 2CSK_N[23-157] | HisKA[237-301] | HATPase_c[349-447]
  • Domain count: 3
  • Matched identifier: HKOC_1906009
  • Positioned domains: 2CSK_N 23-157 ; HisKA 237-301 ; HATPase_c 349-447
Cluster members and taxonomy
Visualization

Representative gene: GCF_022396775#LCT52_RS05405

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 169 664 · GCF_000304255
AssemblyECAD30.1 · Contighaploid
Genome composition5 077 949 bp · 50,5% GCEscherichia coli AD30
Signal transduction countsGenes 62 · HK 30 · RR 32CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia

Related genes

Preview from the same derived genome key