Gene detail

ECAD30_RS02195

Histidine kinase, Classic

Escherichia coli AD30 · GCF_000304255

ClassHKTypeClassicLength458 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000304255#ECAD30_RS02195Stable P2CS identifier used across views.
GenomeGCF_000304255Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Selected clusterHKOC_1858312Run 6 · 3037 sequences · id 100% · cov 80%
External referencesWP_001211923.1 · A0AAN3ZII1 · MIST4 ECAD30_RS02195RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length458 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage170 / 458 aa (37.1%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa458 aa
HisKA: 237-299 aa (63 aa)1HATPase_c: 345-451 aa (107 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
237-299 aa · 63 aa · 13.8% of protein
Raw tokenHisKA:237:0.00000000000102:299:63:64
2 HATPase_c#2
345-451 aa · 107 aa · 23.4% of protein
Raw tokenHATPase_c:345:1.75e-32:451:110:109
  • Raw architecture: HisKA:237:0.00000000000102:299:63:64#HATPase_c:345:1.75e-32:451:110:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000304255::NZ_AMSK01000037.1::G00036
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span3236-5934Genomic interval covered by the local TCS group.
Identifiers
Old locus tagECAD30_44270RefSeq proteinWP_001211923.1
Context group IDGCF_000304255::NZ_AMSK01000037.1::G00036
Context members
ECAD30_RS02200ECAD30_RS02195
Partner locus tags
ECAD30_RS02200ECAD30_RS02195
Partner old locus tags
ECAD30_44260ECAD30_44270
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_001211923.1Primary protein accession used for annex mappings.
UniProt accessionA0AAN3ZII1Primary UniProt accession resolved in the annex database.
UniProt IDA0AAN3ZII1_SHIDYDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagECAD30_RS02195Primary locus identifier stored in the genes table.
Old locus tagECAD30_44270Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AMSK01000037.1Sequence record reported by the local genomic context database.
Genomic interval4 558-5 934 nt1 377 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span3 236-5 934 ntGCF_000304255::NZ_AMSK01000037.1::G00036

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000304255::NZ_AMSK01000037.1::G00036

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AMSK01000037.1All displayed genes belong to this local TCS context.
Neighborhood span3 236-5 934 nt2 699 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
3 236 nt5 934 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

ECAD30_RS02200GCF_000304255#ECAD30_RS02200
RRNtrC

3 236-4 561 nt · Reverse (-)

Old locus ECAD30_44260RefSeq WP_000148558.1
ECAD30_RS02195GCF_000304255#ECAD30_RS02195
HKClassicCurrent focus

4 558-5 934 nt · Reverse (-)

Old locus ECAD30_44270RefSeq WP_001211923.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1858312Run 6 · HK · 3037 sequences
Representative sequenceGCF_000019385#ECOLC_RS21635Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1858312

Simplified PFAM architecture for HKOC_1858312

PFAM domain coverage: 168 / 458 aa (36.7%)

1 aa458 aa
HisKA: 238-300 aaHisKAHATPase_c: 346-450 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[238-300] | HATPase_c[346-450]
  • Domain count: 2
  • Matched identifier: HKOC_1858312
  • Positioned domains: HisKA 238-300 ; HATPase_c 346-450
Cluster members and taxonomy
Visualization

Representative gene: GCF_000019385#ECOLC_RS21635

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 169 664 · GCF_000304255
AssemblyECAD30.1 · Contighaploid
Genome composition5 077 949 bp · 50,5% GCEscherichia coli AD30
Signal transduction countsGenes 62 · HK 30 · RR 32CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia

Related genes

Preview from the same derived genome key