Gene detail

ETEC_RS07270

Histidine kinase, Classic

Escherichia coli ETEC H10407 · GCF_000210475

ClassHKTypeClassicLength598 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000210475#ETEC_RS07270Stable P2CS identifier used across views.
GenomeGCF_000210475Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Selected clusterHKOC_1061661Run 6 · 8 sequences · id 100% · cov 80% · representative
External referencesWP_000918077.1 · MIST4 ETEC_RS07270RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

PilJHAMPHisKA_3HATPase_c
Protein length598 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage314 / 598 aa (52.5%)Merged over positioned domains only.
Domain description1 PilJ,1 HAMP,1 HisKA_3,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa598 aa
PilJ: 35-128 aa (94 aa)1HAMP: 158-225 aa (68 aa)2HisKA_3: 390-453 aa (64 aa)3HATPase_c: 496-583 aa (88 aa)4
Domain-by-domain annotation4 items
1 PilJ#1
35-128 aa · 94 aa · 15.7% of protein
Raw tokenPilJ:35:0.00000000673:128:112:112
2 HAMP#2
158-225 aa · 68 aa · 11.4% of protein
Raw tokenHAMP:158:0.0000000000593:225:69:69
3 HisKA_3#3
390-453 aa · 64 aa · 10.7% of protein
Raw tokenHisKA_3:390:4.33e-17:453:64:68
4 HATPase_c#4
496-583 aa · 88 aa · 14.7% of protein
Raw tokenHATPase_c:496:5.24e-20:583:103:109
  • Raw architecture: PilJ:35:0.00000000673:128:112:112#HAMP:158:0.0000000000593:225:69:69#HisKA_3:390:4.33e-17:453:64:68#HATPase_c:496:5.24e-20:583:103:109
  • Domain description: 1 PilJ,1 HAMP,1 HisKA_3,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000210475::NC_017633.1::G00011
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span1415606-1418045Genomic interval covered by the local TCS group.
Identifiers
Old locus tagETEC_1329RefSeq proteinWP_000918077.1
Context group IDGCF_000210475::NC_017633.1::G00011
Context members
ETEC_RS07265ETEC_RS07270
Partner locus tags
ETEC_RS07265ETEC_RS07270
Partner old locus tags
ETEC_1328ETEC_1329
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_000918077.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagETEC_RS07270Primary locus identifier stored in the genes table.
Old locus tagETEC_1329Legacy locus tag recovered from the local context mapping.
Contig / repliconNC_017633.1Sequence record reported by the local genomic context database.
Genomic interval1 416 249-1 418 045 nt1 797 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span1 415 606-1 418 045 ntGCF_000210475::NC_017633.1::G00011

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000210475::NC_017633.1::G00011

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNC_017633.1All displayed genes belong to this local TCS context.
Neighborhood span1 415 606-1 418 045 nt2 440 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 415 606 nt1 418 045 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

ETEC_RS07265GCF_000210475#ETEC_RS07265
RRNarL

1 415 606-1 416 256 nt · Reverse (-)

Old locus ETEC_1328RefSeq WP_000070491.1
ETEC_RS07270GCF_000210475#ETEC_RS07270
HKClassicCurrent focus

1 416 249-1 418 045 nt · Reverse (-)

Old locus ETEC_1329RefSeq WP_000918077.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1061661Run 6 · HK · 8 sequences
Representative sequenceGCF_000210475#ETEC_RS07270The current gene is the representative for this cluster.
PFAM architecturePilJ + HAMP + HisKA_3 + HATPase_c4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1061661

Simplified PFAM architecture for HKOC_1061661

PFAM domain coverage: 301 / 598 aa (50.3%)

1 aa598 aa
PilJ: 35-129 aaPilJHAMP: 173-224 aaHAMPHisKA_3: 390-453 aaHisKA_3HATPase_c: 496-585 aaHATPase_c
PilJHAMPHisKA_3HATPase_c
  • Simplified architecture: PilJ + HAMP + HisKA_3 + HATPase_c
  • Raw architecture: PilJ[35-129] | HAMP[173-224] | HisKA_3[390-453] | HATPase_c[496-585]
  • Domain count: 4
  • Matched identifier: HKOC_1061661
  • Positioned domains: PilJ 35-129 ; HAMP 173-224 ; HisKA_3 390-453 ; HATPase_c 496-585
Cluster members and taxonomy
Visualization

Representative gene: GCF_000210475#ETEC_RS07270

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 316 401 · GCF_000210475
AssemblyASM21047v1 · Complete Genomehaploid
Genome composition5 325 888 bp · 50,5% GCEscherichia coli ETEC H10407
Signal transduction countsGenes 68 · HK 33 · RR 35CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia

Related genes

Preview from the same derived genome key