1 HAMP#1
173-242 aa · 70 aa · 15.0% of protein
Raw token
HAMP:173:0.00000000106:242:70:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
ETEC_RS01265
Histidine kinase, Classic
Escherichia coli ETEC H10407 · GCF_000210475
ClassHKTypeClassicLength466 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000210475#ETEC_RS01265Stable P2CS identifier used across views.
GenomeGCF_000210475Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length466 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage245 / 466 aa (52.6%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa466 aa
Domain-by-domain annotation3 items
2 HisKA#2
247-313 aa · 67 aa · 14.4% of protein
Raw token
HisKA:247:0.0000000000044:313:67:643 HATPase_c#3
356-463 aa · 108 aa · 23.2% of protein
Raw token
HATPase_c:356:1.15e-23:463:111:109- Raw architecture: HAMP:173:0.00000000106:242:70:69#HisKA:247:0.0000000000044:313:67:64#HATPase_c:356:1.15e-23:463:111:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000210475::NC_017633.1::G00002
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span266839-268916Genomic interval covered by the local TCS group.
Identifiers
Old locus tagETEC_0236RefSeq proteinWP_001211180.1
Context group ID
GCF_000210475::NC_017633.1::G00002Context members
ETEC_RS01260ETEC_RS01265
Partner locus tags
ETEC_RS01260ETEC_RS01265
Partner old locus tags
ETEC_0235ETEC_0236
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_001211180.1Primary protein accession used for annex mappings.
UniProt accessionA0A7W3EKS7Primary UniProt accession resolved in the annex database.
UniProt IDA0A7W3EKS7_ESCFEDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagETEC_RS01265Primary locus identifier stored in the genes table.
Old locus tagETEC_0236Legacy locus tag recovered from the local context mapping.
Contig / repliconNC_017633.1Sequence record reported by the local genomic context database.
Genomic interval267 516-268 916 nt1 401 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span266 839-268 916 ntGCF_000210475::NC_017633.1::G00002
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000210475::NC_017633.1::G00002Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNC_017633.1All displayed genes belong to this local TCS context.
Neighborhood span266 839-268 916 nt2 078 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
266 839 nt268 916 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
ETEC_RS01260GCF_000210475#ETEC_RS01260
RROmpR
266 839-267 519 nt · Forward (+)
ETEC_RS01265GCF_000210475#ETEC_RS01265
HKClassicCurrent focus
267 516-268 916 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_009822355#FHE88_RS17635Use this link to inspect the representative gene detail.
PFAM architectureCusS + HAMP + HisKA + HATPase_c4 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1678658
Simplified PFAM architecture for HKOC_1678658
PFAM domain coverage: 388 / 474 aa (81.9%)
1 aa474 aa
CusSHAMPHisKAHATPase_c
- Simplified architecture: CusS + HAMP + HisKA + HATPase_c
- Raw architecture: CusS[5-166] | HAMP[191-242] | HisKA[248-313] | HATPase_c[356-463]
- Domain count: 4
- Matched identifier: HKOC_1678658
- Positioned domains: CusS 5-166 ; HAMP 191-242 ; HisKA 248-313 ; HATPase_c 356-463
Cluster members and taxonomy
Representative gene: GCF_009822355#FHE88_RS17635
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 316 401 · GCF_000210475
AssemblyASM21047v1 · Complete Genomehaploid
Genome composition5 325 888 bp · 50,5% GCEscherichia coli ETEC H10407
Signal transduction countsGenes 68 · HK 33 · RR 35CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia
Related genes
Preview from the same derived genome key