1 HAMP#1
188-258 aa · 71 aa · 14.5% of protein
Raw token
HAMP:188:0.00000000048:258:71:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
ETEC_RS01165
Histidine kinase, Classic
Escherichia coli ETEC H10407 · GCF_000210475
ClassHKTypeClassicLength491 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000210475#ETEC_RS01165Stable P2CS identifier used across views.
GenomeGCF_000210475Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length491 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage247 / 491 aa (50.3%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa491 aa
Domain-by-domain annotation3 items
2 HisKA#2
262-328 aa · 67 aa · 13.6% of protein
Raw token
HisKA:262:0.00000000000978:328:67:643 HATPase_c#3
372-480 aa · 109 aa · 22.2% of protein
Raw token
HATPase_c:372:7.41e-29:480:110:109- Raw architecture: HAMP:188:0.00000000048:258:71:69#HisKA:262:0.00000000000978:328:67:64#HATPase_c:372:7.41e-29:480:110:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000210475::NC_017633.1::G00001
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span246259-248407Genomic interval covered by the local TCS group.
Identifiers
Old locus tagETEC_0217RefSeq proteinWP_000555731.1
Context group ID
GCF_000210475::NC_017633.1::G00001Context members
ETEC_RS01165ETEC_RS01170
Partner locus tags
ETEC_RS01165ETEC_RS01170
Partner old locus tags
ETEC_0217ETEC_0218
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_000555731.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagETEC_RS01165Primary locus identifier stored in the genes table.
Old locus tagETEC_0217Legacy locus tag recovered from the local context mapping.
Contig / repliconNC_017633.1Sequence record reported by the local genomic context database.
Genomic interval246 259-247 734 nt1 476 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span246 259-248 407 ntGCF_000210475::NC_017633.1::G00001
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000210475::NC_017633.1::G00001Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNC_017633.1All displayed genes belong to this local TCS context.
Neighborhood span246 259-248 407 nt2 149 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
246 259 nt248 407 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
ETEC_RS01165GCF_000210475#ETEC_RS01165
HKClassicCurrent focus
246 259-247 734 nt · Reverse (-)
ETEC_RS01170GCF_000210475#ETEC_RS01170
RROmpR
247 727-248 407 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000210475#ETEC_RS01165The current gene is the representative for this cluster.
PFAM architectureCusS + HAMP + HisKA + HATPase_c4 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1527134
Simplified PFAM architecture for HKOC_1527134
PFAM domain coverage: 399 / 491 aa (81.3%)
1 aa491 aa
CusSHAMPHisKAHATPase_c
- Simplified architecture: CusS + HAMP + HisKA + HATPase_c
- Raw architecture: CusS[8-181] | HAMP[208-257] | HisKA[263-327] | HATPase_c[372-481]
- Domain count: 4
- Matched identifier: HKOC_1527134
- Positioned domains: CusS 8-181 ; HAMP 208-257 ; HisKA 263-327 ; HATPase_c 372-481
Cluster members and taxonomy
Representative gene: GCF_000210475#ETEC_RS01165
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 316 401 · GCF_000210475
AssemblyASM21047v1 · Complete Genomehaploid
Genome composition5 325 888 bp · 50,5% GCEscherichia coli ETEC H10407
Signal transduction countsGenes 68 · HK 33 · RR 35CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia
Related genes
Preview from the same derived genome key