1 PAS#1
98-194 aa · 97 aa · 22.5% of protein
Raw token
PAS:98:0.00000000000231:194:113:113P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
ETEC_RS02435
Histidine kinase, Classic
Escherichia coli ETEC H10407 · GCF_000210475
ClassHKTypeClassicLength431 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000210475#ETEC_RS02435Stable P2CS identifier used across views.
GenomeGCF_000210475Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Domain signature
Compact overview inferred from the domain field
PASHisKAHATPase_c
Protein length431 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage275 / 431 aa (63.8%)Merged over positioned domains only.
Domain description1 PAS,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa431 aa
Domain-by-domain annotation3 items
2 HisKA#2
203-268 aa · 66 aa · 15.3% of protein
Raw token
HisKA:203:1.27e-19:268:66:643 HATPase_c#3
313-424 aa · 112 aa · 26.0% of protein
Raw token
HATPase_c:313:1.13e-33:424:112:109- Raw architecture: PAS:98:0.00000000000231:194:113:113#HisKA:203:1.27e-19:268:66:64#HATPase_c:313:1.13e-33:424:112:109
- Domain description: 1 PAS,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000210475::NC_017633.1::G00003
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span478136-480178Genomic interval covered by the local TCS group.
Identifiers
Old locus tagETEC_0452RefSeq proteinWP_000893574.1
Context group ID
GCF_000210475::NC_017633.1::G00003Context members
ETEC_RS02430ETEC_RS02435
Partner locus tags
ETEC_RS02430ETEC_RS02435
Partner old locus tags
ETEC_0451ETEC_0452
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_000893574.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagETEC_RS02435Primary locus identifier stored in the genes table.
Old locus tagETEC_0452Legacy locus tag recovered from the local context mapping.
Contig / repliconNC_017633.1Sequence record reported by the local genomic context database.
Genomic interval478 883-480 178 nt1 296 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span478 136-480 178 ntGCF_000210475::NC_017633.1::G00003
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000210475::NC_017633.1::G00003Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNC_017633.1All displayed genes belong to this local TCS context.
Neighborhood span478 136-480 178 nt2 043 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
478 136 nt480 178 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
ETEC_RS02430GCF_000210475#ETEC_RS02430
RROmpR
478 136-478 825 nt · Forward (+)
ETEC_RS02435GCF_000210475#ETEC_RS02435
HKClassicCurrent focus
478 883-480 178 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000210475#ETEC_RS02435The current gene is the representative for this cluster.
PFAM architecturePhoR + PAS + HisKA + HATPase_c4 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2161465
Simplified PFAM architecture for HKOC_2161465
PFAM domain coverage: 360 / 431 aa (83.5%)
1 aa431 aa
PhoRPASHisKAHATPase_c
- Simplified architecture: PhoR + PAS + HisKA + HATPase_c
- Raw architecture: PhoR[6-91] | PAS[99-194] | HisKA[203-268] | HATPase_c[313-424]
- Domain count: 4
- Matched identifier: HKOC_2161465
- Positioned domains: PhoR 6-91 ; PAS 99-194 ; HisKA 203-268 ; HATPase_c 313-424
Cluster members and taxonomy
Representative gene: GCF_000210475#ETEC_RS02435
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 316 401 · GCF_000210475
AssemblyASM21047v1 · Complete Genomehaploid
Genome composition5 325 888 bp · 50,5% GCEscherichia coli ETEC H10407
Signal transduction countsGenes 68 · HK 33 · RR 35CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia
Related genes
Preview from the same derived genome key