1 HAMP#1
173-242 aa · 70 aa · 14.8% of protein
Raw token
HAMP:173:0.00000000134:242:70:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
FHE88_RS17635
Histidine kinase, Classic
Escherichia coli · GCF_009822355
ClassHKTypeClassicLength474 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_009822355#FHE88_RS17635Stable P2CS identifier used across views.
GenomeGCF_009822355Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length474 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage245 / 474 aa (51.7%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa474 aa
Domain-by-domain annotation3 items
2 HisKA#2
247-313 aa · 67 aa · 14.1% of protein
Raw token
HisKA:247:0.00000000000481:313:67:643 HATPase_c#3
356-463 aa · 108 aa · 22.8% of protein
Raw token
HATPase_c:356:1.34e-23:463:111:109- Raw architecture: HAMP:173:0.00000000134:242:70:69#HisKA:247:0.00000000000481:313:67:64#HATPase_c:356:1.34e-23:463:111:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_009822355::NZ_VDHZ01000037.1::G00024
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span40666-42767Genomic interval covered by the local TCS group.
Identifiers
Context group ID
GCF_009822355::NZ_VDHZ01000037.1::G00024Context members
FHE88_RS17630FHE88_RS17635
Partner locus tags
FHE88_RS17630FHE88_RS17635
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_159140184.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagFHE88_RS17635Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_VDHZ01000037.1Sequence record reported by the local genomic context database.
Genomic interval41 343-42 767 nt1 425 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span40 666-42 767 ntGCF_009822355::NZ_VDHZ01000037.1::G00024
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_009822355::NZ_VDHZ01000037.1::G00024Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_VDHZ01000037.1All displayed genes belong to this local TCS context.
Neighborhood span40 666-42 767 nt2 102 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
40 666 nt42 767 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
FHE88_RS17630GCF_009822355#FHE88_RS17630
RROmpR
40 666-41 346 nt · Forward (+)
FHE88_RS17635GCF_009822355#FHE88_RS17635
HKClassicCurrent focus
41 343-42 767 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_009822355#FHE88_RS17635The current gene is the representative for this cluster.
PFAM architectureCusS + HAMP + HisKA + HATPase_c4 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1678658
Simplified PFAM architecture for HKOC_1678658
PFAM domain coverage: 388 / 474 aa (81.9%)
1 aa474 aa
CusSHAMPHisKAHATPase_c
- Simplified architecture: CusS + HAMP + HisKA + HATPase_c
- Raw architecture: CusS[5-166] | HAMP[191-242] | HisKA[248-313] | HATPase_c[356-463]
- Domain count: 4
- Matched identifier: HKOC_1678658
- Positioned domains: CusS 5-166 ; HAMP 191-242 ; HisKA 248-313 ; HATPase_c 356-463
Cluster members and taxonomy
Representative gene: GCF_009822355#FHE88_RS17635
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 562 · GCF_009822355
AssemblyASM982235v1 · Scaffoldhaploid
Genome composition4 995 560 bp · 50,5% GCEscherichia coli
Signal transduction countsGenes 66 · HK 32 · RR 34CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia
Related genes
Preview from the same derived genome key