Gene detail

ACFY52_RS06295

Histidine kinase, Classic

Mediterraneibacter gnavus · GCF_964272155

ClassHKTypeClassicLength361 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_964272155#ACFY52_RS06295Stable P2CS identifier used across views.
GenomeGCF_964272155Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Mediterraneibacter
Selected clusterHKOC_2741907Run 6 · 36 sequences · id 100% · cov 80%
External referencesWP_022037919.1 · A0A2N5NMW7 · MIST4 ACFY52_RS06295RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length361 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage246 / 361 aa (68.1%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa361 aa
HAMP: 59-128 aa (70 aa)1HisKA: 135-200 aa (66 aa)2HATPase_c: 245-354 aa (110 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
59-128 aa · 70 aa · 19.4% of protein
Raw tokenHAMP:59:0.0000297:128:70:69
2 HisKA#2
135-200 aa · 66 aa · 18.3% of protein
Raw tokenHisKA:135:1.91e-17:200:66:64
3 HATPase_c#3
245-354 aa · 110 aa · 30.5% of protein
Raw tokenHATPase_c:245:2.38e-32:354:110:109
  • Raw architecture: HAMP:59:0.0000297:128:70:69#HisKA:135:1.91e-17:200:66:64#HATPase_c:245:2.38e-32:354:110:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_964272155::NZ_OZ186737.1::G00022
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span1247719-1249472Genomic interval covered by the local TCS group.
Context group IDGCF_964272155::NZ_OZ186737.1::G00022
Context members
ACFY52_RS06290ACFY52_RS06295
Partner locus tags
ACFY52_RS06290ACFY52_RS06295
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_022037919.1Primary protein accession used for annex mappings.
UniProt accessionA0A2N5NMW7Primary UniProt accession resolved in the annex database.
UniProt IDA0A2N5NMW7_MEDGNDisplay identifier provided by UniProt.
GO / PubMed2 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagACFY52_RS06295Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_OZ186737.1Sequence record reported by the local genomic context database.
Genomic interval1 248 387-1 249 472 nt1 086 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span1 247 719-1 249 472 ntGCF_964272155::NZ_OZ186737.1::G00022

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_964272155::NZ_OZ186737.1::G00022

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_OZ186737.1All displayed genes belong to this local TCS context.
Neighborhood span1 247 719-1 249 472 nt1 754 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 247 719 nt1 249 472 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

ACFY52_RS06290GCF_964272155#ACFY52_RS06290
RROmpR

1 247 719-1 248 390 nt · Forward (+)

RefSeq WP_009243908.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2741907Run 6 · HK · 36 sequences
Representative sequenceGCF_002865285#CDL20_RS01960Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2741907

Simplified PFAM architecture for HKOC_2741907

PFAM domain coverage: 174 / 361 aa (48.2%)

1 aa361 aa
HisKA: 135-199 aaHisKAHATPase_c: 246-354 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[135-199] | HATPase_c[246-354]
  • Domain count: 2
  • Matched identifier: HKOC_2741907
  • Positioned domains: HisKA 135-199 ; HATPase_c 246-354
Cluster members and taxonomy
Visualization

Representative gene: GCF_002865285#CDL20_RS01960

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 33 038 · GCF_964272155
AssemblyLUMC_Rgna_QRD044 · Complete Genomehaploid
Genome composition3 128 629 bp · 43,5% GCMediterraneibacter gnavus
Signal transduction countsGenes 80 · HK 38 · RR 41CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusMediterraneibacter
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Mediterraneibacter

Related genes

Preview from the same derived genome key