1 HisKA#1
492-556 aa · 65 aa · 9.0% of protein
Raw token
HisKA:492:0.00000000000000673:556:65:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
ACFY52_RS00930
Histidine kinase, Classic
Mediterraneibacter gnavus · GCF_964272155
ClassHKTypeClassicLength723 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_964272155#ACFY52_RS00930Stable P2CS identifier used across views.
GenomeGCF_964272155Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Mediterraneibacter
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length723 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage155 / 723 aa (21.4%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa723 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
609-698 aa · 90 aa · 12.4% of protein
Raw token
HATPase_c:609:0.0000000000491:698:94:109- Raw architecture: HisKA:492:0.00000000000000673:556:65:64#HATPase_c:609:0.0000000000491:698:94:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_964272155::NZ_OZ186737.1::G00003
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span199347-202188Genomic interval covered by the local TCS group.
Identifiers
Context group ID
GCF_964272155::NZ_OZ186737.1::G00003Context members
ACFY52_RS00925ACFY52_RS00930
Partner locus tags
ACFY52_RS00925ACFY52_RS00930
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_022037136.1Primary protein accession used for annex mappings.
UniProt accessionA0A2N5PKK1Primary UniProt accession resolved in the annex database.
UniProt IDA0A2N5PKK1_MEDGNDisplay identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
Reference hubs
GO terms
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagACFY52_RS00930Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_OZ186737.1Sequence record reported by the local genomic context database.
Genomic interval200 017-202 188 nt2 172 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span199 347-202 188 ntGCF_964272155::NZ_OZ186737.1::G00003
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_964272155::NZ_OZ186737.1::G00003Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_OZ186737.1All displayed genes belong to this local TCS context.
Neighborhood span199 347-202 188 nt2 842 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
199 347 nt202 188 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
ACFY52_RS00925GCF_964272155#ACFY52_RS00925
RROmpR
199 347-200 045 nt · Forward (+)
ACFY52_RS00930GCF_964272155#ACFY52_RS00930
HKClassicCurrent focus
200 017-202 188 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_002865305#CDL24_RS12355Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_0727133
Simplified PFAM architecture for HKOC_0727133
PFAM domain coverage: 161 / 723 aa (22.3%)
1 aa723 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[492-556] | HATPase_c[604-699]
- Domain count: 2
- Matched identifier: HKOC_0727133
- Positioned domains: HisKA 492-556 ; HATPase_c 604-699
Cluster members and taxonomy
Representative gene: GCF_002865305#CDL24_RS12355
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 33 038 · GCF_964272155
AssemblyLUMC_Rgna_QRD044 · Complete Genomehaploid
Genome composition3 128 629 bp · 43,5% GCMediterraneibacter gnavus
Signal transduction countsGenes 80 · HK 38 · RR 41CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusMediterraneibacter
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Mediterraneibacter
Related genes
Preview from the same derived genome key