1 dCache_1#1
208-309 aa · 102 aa · 15.7% of protein
Raw token
dCache_1:208:0.0000000234:309:105:195P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
ACFY52_RS01610
Histidine kinase, Classic
Mediterraneibacter gnavus · GCF_964272155
ClassHKTypeClassicLength651 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_964272155#ACFY52_RS01610Stable P2CS identifier used across views.
GenomeGCF_964272155Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Mediterraneibacter
Domain signature
Compact overview inferred from the domain field
dCache_1HAMPHis_kinaseHATPase_c
Protein length651 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage359 / 651 aa (55.1%)Merged over positioned domains only.
Domain description1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa651 aa
Domain-by-domain annotation4 items
2 HAMP#2
333-402 aa · 70 aa · 10.8% of protein
Raw token
HAMP:333:0.00000000000151:402:70:693 His_kinase#3
424-505 aa · 82 aa · 12.6% of protein
Raw token
His_kinase:424:6.04e-23:505:82:804 HATPase_c#4
524-628 aa · 105 aa · 16.1% of protein
Raw token
HATPase_c:524:0.00000000000368:628:108:109- Raw architecture: dCache_1:208:0.0000000234:309:105:195#HAMP:333:0.00000000000151:402:70:69#His_kinase:424:6.04e-23:505:82:80#HATPase_c:524:0.00000000000368:628:108:109
- Domain description: 1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_964272155::NZ_OZ186737.1::G00006
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span330213-333666Genomic interval covered by the local TCS group.
Identifiers
Context group ID
GCF_964272155::NZ_OZ186737.1::G00006Context members
ACFY52_RS01610ACFY52_RS01615
Partner locus tags
ACFY52_RS01610ACFY52_RS01615
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_101874744.1Primary protein accession used for annex mappings.
UniProt accessionA0A9Q4F1E4Primary UniProt accession resolved in the annex database.
UniProt IDA0A9Q4F1E4_MEDGNDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagACFY52_RS01610Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_OZ186737.1Sequence record reported by the local genomic context database.
Genomic interval330 213-332 168 nt1 956 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span330 213-333 666 ntGCF_964272155::NZ_OZ186737.1::G00006
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_964272155::NZ_OZ186737.1::G00006Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_OZ186737.1All displayed genes belong to this local TCS context.
Neighborhood span330 213-333 666 nt3 454 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
330 213 nt333 666 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
ACFY52_RS01610GCF_964272155#ACFY52_RS01610
HKClassicCurrent focus
330 213-332 168 nt · Forward (+)
ACFY52_RS01615GCF_964272155#ACFY52_RS01615
RRunclassified
332 143-333 666 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_002865305#CDL24_RS06120Use this link to inspect the representative gene detail.
PFAM architecturedCache_1 + HAMP + His_kinase + HATPase_c4 domains in the representative PFAM annotation.
PFAM architecture for HKOC_0894699
Simplified PFAM architecture for HKOC_0894699
PFAM domain coverage: 478 / 651 aa (73.4%)
1 aa651 aa
dCache_1HAMPHis_kinaseHATPase_c
- Simplified architecture: dCache_1 + HAMP + His_kinase + HATPase_c
- Raw architecture: dCache_1[70-311] | HAMP[351-400] | His_kinase[424-504] | HATPase_c[524-628]
- Domain count: 4
- Matched identifier: HKOC_0894699
- Positioned domains: dCache_1 70-311 ; HAMP 351-400 ; His_kinase 424-504 ; HATPase_c 524-628
Cluster members and taxonomy
Representative gene: GCF_002865305#CDL24_RS06120
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 33 038 · GCF_964272155
AssemblyLUMC_Rgna_QRD044 · Complete Genomehaploid
Genome composition3 128 629 bp · 43,5% GCMediterraneibacter gnavus
Signal transduction countsGenes 80 · HK 38 · RR 41CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusMediterraneibacter
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Mediterraneibacter
Related genes
Preview from the same derived genome key